About Desafia
Desafia, an accelerator and incubator program founded in 2011, is based in San Francisco, United States. With a presence in 6 countries, it has supported around 89 startups in sectors like Enterprise Applications, High Tech. As of Apr 2026, Desafia has witnessed 8 portfolio exits. Most notable companies in
its portfolio include Wallbox, RubiconMD and BYHOURS. The program primarily supports Seed startups based in Spain. Its latest investment was a Undisclosed Seed round in Docxpresso on Oct 24, 2018.
Key Metrics
Founded Year
2011
Location
San Francisco, United States
Sectors of Investment
Stages of Investment
Seed
Locations of Investment
Desafia's List of Top Investments
Desafia has a portfolio of 89 companies. Their most notable investmentis in DocxpressoTheir portfolio spans across Spain, United States, Canada and 3 more locations. They have invested in Enterprise Applications, High Tech, Consumer and 26 other sectors, across stages such as Seed stage. Here is the list of top investments by Desafia:1. Wallbox
Provider of electric-vehicle charging solutions. It designs and manufactures electric-vehicle plug-in charging solutions for personal and commercial purposes. It offers various products offers compact charging solutions for cars, and copper can be used for commercial purposes and semi-public use. It offers touchscreen-enabled charging solutions at corporate parking and others. The mobile application is available for android users.
Key facts about Wallbox
- Founded Year: 2015
- Location: Barcelona (Spain)
- Stage: Public
- Total Funding till date: $70.2M
- Employee Count: 1 as on Mar 31, 2024
- Investors: Seaya, Cathay Innovation and 16 Others
- Latest Funding Round: Post IPO, Jun 05, 2025, $*****
- Highlight: Public

2. RubiconMD
Virtual specialty care platform connecting primary care with specialist expertise. This platform offers accessible specialty care solutions through a configurable eConsult platform, connecting primary care providers to a comprehensive specialist network. It facilitates program design and development for targeted specialty care support, diagnosis, treatment, and disease management. The platform enhances care models by providing access to board-certified specialists, promoting impactful, comprehensive, and cost-effective primary care. It aims to make medical expertise accessible to everyone, regardless of location or background. The company provides resources like a blog, case library, CME webinars, and a learning center. It is an information service and does not provide medical diagnosis or treatment. The platform offers login functionality and encourages users to sign up for updates. This is a B2B platform.
Key facts about RubiconMD
- Founded Year: 2013
- Location: New York City (United States)
- Stage: Acquired
- Total Funding till date: $37.8M
- Employee Count: 62 as on Dec 31, 2022
- Investors: Deerfield, Catapult and 19 Others
- Latest Funding Round: Series C, Feb 24, 2020, $*****
- Highlight: Acquired

3. BYHOURS
Online platform for booking hourly-based hotels accommodations. Users can book hotel rooms by the hour after providing travel details such as destinations, arrival times and time-slots. The platform also enables interested hoteliers to sign up on the platform. App is available for iOS and Android devices.
Key facts about BYHOURS
- Founded Year: 2012
- Location: Barcelona (Spain)
- Stage: Series B
- Total Funding till date: $22M
- Employee Count: 51 - 200 as on Jul 01, 2024
- Investors: Verve Ventures, Axon Partners Group and 13 Others
- Latest Funding Round: Series B, Nov 20, 2023, $*****
- Highlight: Editors' Pick
Software-based platform for financial data and analytics solutions. It offers data solutions for categorization, insights, auto savings, enrichment, loyalty, carbon footprint tracking, insurance, and more.
Key facts about Coinscrap Finance
- Founded Year: 2016
- Location: Pontevedra (Spain)
- Stage: Seed
- Total Funding till date: $2.79M
- Employee Count: 24 as on Mar 31, 2026
- Investors: b2venture, Draper Venture Network and 13 Others
- Latest Funding Round: Seed, Aug 10, 2021, $*****
- Highlight: Editors' Pick
5. Amadix
Provider of diagnostic tools to support personalized cancer treatment. The company has developed prognostic, diagnostic, and predictive tests for lung cancer, colorectal cancer, and prostate cancer. Its colon cancer test ColoFast is a blood-based miRNA test for early detection of colon cancer. It is also developing DiagnoLung which is a blood-based ELISA test that measures the level of three protein biomarkers to screen high-risk patients for non-small-cell lung cancer.
Key facts about Amadix
- Founded Year: 2010
- Location: Madrid (Spain)
- Stage: Series A
- Total Funding till date: $6.87M
- Employee Count: 25 as on Jul 01, 2024
- Investors: Inveready, European Investment Bank and 8 Others
- Latest Funding Round: Venture Debt, Feb 14, 2025, $*****
- Highlight: Editors' Pick
Desafia's Year-on-Year Investment Trends
Its most recent first time investment was in Docxpresso.Desafia's Investments by Stage
Desafia has made 1 investment in Seed stage.Desafia's Investments by Sector
Desafia has a portfolio focused on Enterprise Applications. Notably, it has invested in 74 Tech companies, 61 Enterprise (B2B) companies, 54 Software companies and at least 31 companies focusing on Saas.Desafia's Investments by Geography
Desafia has made most investments in Spain (1).Desafia's recent investments
Desafia has not made any investment in 2026 so far.Here are the most recent investments by Desafia:
Date | Company | Location | Round Details | Round Amount | Co-Investors |
|---|---|---|---|---|---|
Oct 24, 2018 | Spain | Seed | 7355 | - |
IPOs and Publicly Listed companies in Desafia's Portfolio
2 of Desafia's portfolio companies have become public. Wallbox got listed on the New York Stock Exchange (NYSE), in Oct 2021 and Cuatroochenta got listed on the Madrid Stock Exchange (BME).Here are Desafia's portfolio companies that went public:
Company | IPO Date | First Invested on | First Round of Investment | Round Size |
|---|---|---|---|---|
Oct 04, 2021 | - | - | 1205 | |
Oct 23, 2020 | - | - | 1837 |
Acquired companies in Desafia's Portfolio
6 companies from Desafia's portfolio have been acquired. The most recent acquisition were Wide Eyes in Jul 2023 by Stylitics.Here are Desafia's portfolio companies that got acquired most recently:
Company | Acquisition Date | First Invested on | First Round of Investment | Round Size |
|---|---|---|---|---|
Jul 11, 2023 | - | - | 8706 | |
Sep 28, 2022 | - | - | 7917 | |
Jun 28, 2022 | - | - | 2544 | |
May 30, 2022 | - | - | 3769 | |
Oct 21, 2021 | - | - | 1970 |