About .406 Ventures
.406 Ventures is a venture capital firm founded in 2005. It is primarily based out of Boston, United States. As of Feb 2026, .406 Ventures is an active investor, having invested in 99 companies, with 1 new investment in the last 12 months. It primarily invests in Series A round in United States based startups. Its investments are spread across a wide range of sectors from Enterprise Applications to HealthTech and Enterprise Infrastructure. Most recently it participated in the $***** Series C round of BigHealth Overall, .406 Ventures portfolio has seen 2 IPOs and 38 acquisitions including key companies like Compass, VMware and Kaltura. A lot of funds co-invest with .406 Ventures, with names like F-Prime Capital sharing a substantial percentage of its portfolio. .406 Ventures has team of 32 people including 8 partners.Key Metrics
Team Members
Portfolio Sectors
Portfolio Locations
Rounds of Entry
Series A, Seed & 5 more
Portfolio Acquisitions
Portfolio Soonicorns
Deals in last 12 months
.406 Ventures' List of Top Investments
.406 Ventures has a portfolio of 99 companies. Their most notable investments are in Nema and Hurdle Health.Their portfolio spans across United States, United Kingdom, Germany and 1 more locations. They have invested in Enterprise Applications, HealthTech, Enterprise Infrastructure and 16 other sectors, across stages such as Series A, Seed and 5 more. Here is the list of top investments by .406 Ventures:1. Compass
Real estate company that helps people buy, sell, and rent homes and apartments. The platform enables users to own a property by discovering properties to seal the deal. Users can browse listings and schedule viewings via the app. The apps are available for Android and iOS devices.
Key facts about Compass
- Founded Year: 2012
- Location: New York City (United States)
- Annual Revenue: $6.96B as on Dec 31, 2025
- Stage: Public
- Total Funding till date: $1.51B
- Employee Count: 34,940 as on Apr 30, 2026
- Investors: Dragoneer Investment Group, CLI Ventures and 42 Others
- Latest Funding Round: Post IPO, Jan 16, 2026, $*****
- Highlight: Public
2. VMware
Cloud based orchestration solutions. It enables running any app on any cloud on any device through the solutions for modern apps, multi-cloud, and digital workspace. It transform data centers into aggregated computing infrastructures with VMware vSphere, its virtualization platform.
Key facts about VMware
- Founded Year: 1998
- Location: Palo Alto (United States)
- Annual Revenue: $13.4B as on Jan 31, 2023
- Last Known Valuation: $*****
- Stage: Acquired
- Total Funding till date: $596M
- Employee Count: 11,436 as on Apr 30, 2026
- Investors: Dell, TD Bank and 31 Others
- Latest Funding Round: Grant (prize money), Jan 01, 2021, $*****
- Highlight: Acquired
3. Kaltura
Provider of video solutions for webinars, events, hubs, and virtual classrooms. The company delivers tools for corporate communication, higher education, marketing, sales, employee training, media, and telecom sectors. It offers an AI video suite, webinars, video portal, events management, and virtual classroom platforms. The company provides solutions for content repurposing, knowledge management, and audience engagement.
Key facts about Kaltura
- Founded Year: 2006
- Location: New York City (United States)
- Annual Revenue: $181M as on Dec 31, 2025
- Stage: Public
- Total Funding till date: $145M
- Employee Count: 721 as on Apr 30, 2026
- Investors: Luminari Capital, .406 Ventures and 16 Others
- Latest Funding Round: Series D, Aug 08, 2016, $*****
- Highlight: Public
4. Veracode
Provider of software security testing and automated code remediation tools. The platform identifies vulnerabilities within application codebases through static and dynamic analysis. It integrates security checks into development workflows to detect flaws in proprietary code, open-source components, and containerized environments. The technology provides automated guidance to assist developers in fixing security issues during the software development lifecycle. Additional offerings include security training modules and hands-on labs for developers to practice secure coding techniques. The system supports governance and compliance by providing visibility into application risk across development pipelines.
Key facts about Veracode
- Founded Year: 2006
- Location: Burlington (United States)
- Annual Revenue: £12.4M as on Dec 31, 2023
- Last Known Valuation: $*****
- Stage: Acquired
- Total Funding till date: $107M
- Employee Count: 505 as on Apr 30, 2026
- Investors: Wellington, In-Q-Tel and 15 Others
- Latest Funding Round: Series F, Jan 01, 2018, $*****
- Highlight: Acquired
5. Carbon Black
Carbon Black provides a cloud endpoint protection platform. The product offers cloud workload protection. The features of the product include attack surface detection and prevention, threat detection, managed detection, alerts, security assessment, vulnerability protection, etc.
Key facts about Carbon Black
- Founded Year: 2002
- Location: San Antonio (United States)
- Last Known Valuation: $*****
- Stage: Acquired
- Total Funding till date: $58.3M
- Employee Count: 253 as on Jan 31, 2026
- Investors: Sequoia Capital, Liberty Global and 13 Others
- Latest Funding Round: Series D, Feb 03, 2016, $*****
- Highlight: Acquired
.406 Ventures' Year-on-Year Investment Trends
.406 Ventures has invested in 99 companies over the last 19 years, with an average of 5 new investments annually in the last 10 years. In 2025, it made 5 investments, while as of Feb 2026, it has made 1 investment in this year. Its most recent first time investment was in BigHealth and most recent follow-on round was in FamilyWell Health.Year | No. of Investments | ||
|---|---|---|---|
1st Round | Follow-on | Total | |
2026 (YTD) | 1 | 0 | 1 |
2025 | 1 | 4 | 5 |
2024 | 4 | 5 | 9 |
2023 | 3 | 7 | 10 |
2022 | 7 | 9 | 16 |
2021 | 7 | 8 | 15 |
2020 | 8 | 11 | 19 |
2019 | 3 | 8 | 11 |
2018 | 7 | 8 | 15 |
2017 | 4 | 8 | 12 |
.406 Ventures' Investments by Stage
.406 Ventures is primarily an Early Stage Investor investor majorly investing in Series A (50) rounds where average round size is $448M, Seed (18) rounds where average round size is $60.4M and Series B (15) rounds where average round size is $244M.Stage of entry | No. of Investments |
|---|---|
Series A | 50 |
Seed | 18 |
Series B | 15 |
Series C | 3 |
Conventional Debt | 1 |
Others | 2 |
Note: We have considered here, only first round of investments
.406 Ventures' Investments by Sector
.406 Ventures has a diverse portfolio, with companies operating in the Enterprise Applications, Enterprise Infrastructure, HealthTech, High Tech and FinTech. Notably, it has invested in 80 Tech companies, 79 Enterprise (B2B) companies, 66 Software companies and at least 41 companies focusing on Saas.Sector | No. of Investments |
|---|---|
Enterprise Applications | 64 |
Enterprise Infrastructure | 34 |
HealthTech | 25 |
High Tech | 13 |
FinTech | 12 |
Others | 68 |
Note: We have considered here, only first round of investments
.406 Ventures' Investments by Geography
.406 Ventures has made most investments in United States (84), followed by United Kingdom where it has made 3 investments.Country | No. of Investments |
|---|---|
United States | 84 |
United Kingdom | 3 |
Germany | 2 |
Israel | 1 |
Note: We have considered here, only first round of investments
.406 Ventures' recent investments
.406 Ventures has made 1 investments in 2026 so far - BigHealth.Here are the most recent investments by .406 Ventures:
Filter this listDate | Company | Location | Round Details | Round Amount | Co-Investors |
|---|---|---|---|---|---|
Feb 12, 2026 | United States | Series C | 6435 | [+5] | |
Nov 18, 2025 | United States | Series A | 6982 | ||
Aug 14, 2025 | United States | Series C | 5739 | [+3] | |
Mar 04, 2025 | - | Series A | 7683 | [+2] | |
Feb 24, 2025 | United States | Series A | 4991 | [+5] |
IPOs and Publicly Listed companies in .406 Ventures' Portfolio
2 of .406 Ventures' portfolio companies have become public. Kaltura got listed on the New York Stock Exchange (NYSE), in Jul 2021 at marketcap of $1.24B and Compass got listed on the New York Stock Exchange (NYSE) at marketcap of $6.96B.Here are .406 Ventures' portfolio companies that went public:
Company | IPO Date | First Invested on | First Round of Investment | Round Size |
|---|---|---|---|---|
Jul 21, 2021 | 2007 | Series A | 1528 | |
Apr 01, 2021 | Sep 25, 2013 | Series A | 6603 |
Acquired companies in .406 Ventures' Portfolio
38 companies from .406 Ventures' portfolio have been acquired. The most recent acquisition was Reltio in Mar 2026 by SAP for $*****.Here are .406 Ventures' portfolio companies that got acquired most recently:
Company | Acquisition Date | First Invested on | First Round of Investment | Round Size |
|---|---|---|---|---|
Mar 26, 2026 | Mar 16, 2015 | Series A | 9930 | |
Feb 23, 2026 | Jun 30, 2021 | Series A | 7139 | |
Sep 09, 2025 | Dec 10, 2019 | Series A | 3752 | |
Mar 06, 2024 | - | - | 5146 | |
Nov 03, 2023 | Nov 09, 2018 | Series A | 8474 |
Team profile of .406 Ventures
.406 Ventures has a team of 32 members including 8 Partners, 12 Venture Partners and 3 Principals located in United States. .406 Ventures' team sits on the board of 10 companies.Here is a list of top team members in .406 Ventures:
Name | Designation | Location | Board Memberships | Contact Details |
|---|---|---|---|---|
Partner | Boston | |||
Partner | United States | - | ||
Partner | Boston | Corvus Insurance, Abacus Insights and 1 more | ||
Partner | Boston | MineralTree, Sevco Security and 2 more | ||
Partner | Boston | MineralTree and Onapsis | - | |
Partner | Boston | |||
Partner | Boston | - | ||
Partner | Boston | - | ||
Venture Partner | Boston | - | ||
Venture Partner | Needham | - | - |
Co-investors of .406 Ventures
Over the past 19 years, 436 investors have co-invested in .406 Ventures's portfolio companies. This includes funds and angels.
- Invested before .406 Ventures: Techstars, Cisco Investments and 101 others have invested in rounds before .406 Ventures. There are 5 companies where Techstars has invested before .406 Ventures and 2 companies where Cisco Investments has invested before .406 Ventures.
- Top Co-investors of .406 Ventures: 134 investors entered a company along with .406 Ventures. These include investors like F-Prime Capital (8 companies).
- Invested after .406 Ventures: A total of 199 investors have invested in .406 Ventures's portfolio after their investments. Top Investors include Eight Roads Ventures (3 companies), CVS Health (3 companies) and Wellington (2 companies).
Recent News related to .406 Ventures
•
Big Health Secures $23.7M in Funding RoundMassinvestor•Feb 13, 2026•DaylightRx, BigHealth, , CVS Health and 7 others
•
Valerie Health Secures $30M Series A for AI Front Office in Independent Provider GroupsBakersfield•Dec 17, 2025•Redpoint Ventures, Valerie Health, .406 Ventures, Karman and 4 others
•
FamilyWell Health Raises $8M to Expand Women’s Mental Health and Menopause CareHIT Consultant•Nov 18, 2025•FamilyWell Health, GreyMatter, New Markets Venture Partners, .406 Ventures and 3 others
•
Diana Health secures $55M to expand women's health programsHIT Consultant•Sep 12, 2025•Diana Health, AlleyCorp, LRVHealth, Health Quest Capital and 3 others
•
Bluebird Kids Health Raises $31.5M for Its Value-Based Pediatric Care Clinics in Underserved AreasMedCity News•Mar 05, 2025•Bluebird Kids, F-Prime Capital, .406 Ventures, Autism Impact Fund and 1 other
•
Rad Security Raises $14 Million For AI, Cloud Security PlatformSecurityWeek•Feb 24, 2025•RAD Security, ForgePoint Capital, Lytical Ventures, Akamai and 3 others
•
RAD Security raises $14M to expand AI-driven cloud security platformSiliconAngle•Feb 24, 2025•RAD Security, Cheyenne Ventures, ForgePoint Capital, Lytical Ventures and 4 others
•
Healthcare payments firm Lynx scores $27 million funding roundFinextra•Feb 06, 2025•Flare Capital Partners, CVS Health Ventures, McKesson Ventures, .406 Ventures and 7 others
•
IntusCare Increases Total Funding to Over $27M through Strategic Follow-On FinancingNews Direct•Jan 16, 2025•Intus Care, Deerfield, Citi, Jumpstart Nova and 5 others
•
Nema Health Raises $14.5 Million Series A to Expand Virtual PTSD Treatment Model and Promote Long-Term HealingPR Newswire•Jan 08, 2025•Nema, Deerfield, CVS Health Ventures, Optum Ventures and 2 others
