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About Codon Capital

Codon Capital is a venture capital firm founded in 2013. It is primarily based out of San Francisco, United States. As of Jan 2026, Codon Capital has invested in 31 companies. It primarily invests in Series A round in United States based startups. Its investments are spread across a wide range of sectors from Life Sciences to High Tech and Food and Agriculture Tech. Most recently it participated in the $***** Series B round of EpiBiologics Overall, Codon Capital portfolio has seen 1 unicorn, 7 IPOs and 8 acquisitions including key companies like RAPT, Kura Oncology and Vaxart. A lot of funds co-invest with Codon Capital, with names like Digitalis Ventures sharing a substantial percentage of its portfolio.
Key Metrics
Portfolio Count
Portfolio Sectors
Portfolio Locations
Rounds of Entry
Series A, Series B & 1 more
Portfolio Acquisitions
Portfolio Unicorns
Portfolio Soonicorns
Deals in last 12 months

Codon Capital's List of Top Investments

Codon Capital has a portfolio of 31 companies, one of which is a Unicorn. Their most notable investmentis in EpiBiologicsTheir portfolio spans across and United States. They have invested in Life Sciences, High Tech, Food and Agriculture Tech and 7 other sectors, across stages such as Series A, Series B  and 1 more. Here is the list of top investments by Codon Capital:
Antheia is focused on developing medicines using its technology. Its technology combines synthetic biology, informatics, and fermentation technology to provide plant-based medicines. It is currently working on engineering the yeast cells genetically to produce natural medicinal products.

Key facts about Antheia

  • Founded Year: 2013
  • Location: Palo Alto (United States)
  • Stage: Series C
  • Total Funding till date: $176M
  • Employee Count: 71 as on Sep 30, 2026
  • Investors: Sherpalo Ventures, SVB and 15 Others
  • Latest Funding Round: Series C, Jan 27, 2026, $*****
  • Highlight: Editors' Pick
Developer of a gene transplantation platform for humanizing pig cells. The company has developed a technology to humanize pig cells that will grow into human-compatible organs. These organs will be harvested in the donor pig and safely transplanted to human patients. The company's technology is based on the next-generation genome engineering toolset and CRISPR.

Key facts about eGenesis

3. RAPT

Rapt is a biopharmaceutical drug developer for oncology and inflammatory diseases based on immunology. It offers its proprietary drug discovery and development platform for small molecules to modulate the immune responses targeting CCR4 (C-C motif chemokine receptor 4). The lead drug candidate of the company is, FLX475 is in phase 1 of the clinical trial, RPT193 in the pre-clinical stage. The company also provides other targets including GCN2 (general control nonderepressible 2) and HPK1 (hematopoietic progenitor kinase 1) for the treatment of cancer.

Key facts about RAPT

Kura Oncology develops targeted small molecule drugs for solid tumours and blood cancer. It's lead candidate tipifarnib, a farnesyl transferase inhibitor, is in Phase II trials for HRAS positive solid tumours and peripheral T-cell lymphomas and has completed phase I trials for myelodysplastic syndrome. In addition, the company is also investigating an ERK inhibitor and Menin MLL inhibitors.

Key facts about Kura Oncology

Provider of DNA synthesis technology using enzymes. The company offers a chemical method and Next-generation technology for synthesis. Their technology is based on polymerase-nucleotide conjugates that have the ability to extend a DNA molecule by one building block at a time.

Key facts about Ansa Biotechnologies

Codon Capital's Investments by Stage

Codon Capital has made 5 investments in Series A stage with an average round size of $47.3M, 2 investments in Series B stage with an average round size of $93.1M and 1 investment in Series C stage with an average round size of $100M.
Here are Codon Capital's investments by stage:
Stage of entry
No. of Investments
Series A
5
Series B
2
Series C
1
Breakdown of Codon Capital's investments by stage of entrySeries A (5)Series B (2)
Note: We have considered here, only first round of investments

Codon Capital's Investments by Sector

Codon Capital has a diverse portfolio, with companies operating in the Life Sciences, High Tech, Sustainability Tech, Chemicals and Materials Tech and Consumer. Notably, it has invested in 30 Tech companies, 27 Enterprise (B2B) companies, 2 Social impact companies and at least 2 companies focusing on Software.
Here are Codon Capital's investments by sector:
Sector
No. of Investments
Life Sciences
7
High Tech
4
Sustainability Tech
2
Chemicals and Materials Tech
1
Consumer
1
Others
4
Breakdown of Codon Capital's investments by sectorsLife Sciences (7)High Tech (4)
Note: We have considered here, only first round of investments

Codon Capital's Investments by Geography

Codon Capital has made most investments in United States (8).

Codon Capital's recent investments

Codon Capital has made 1 investments in 2026 so far - EpiBiologics.
Here are the most recent investments by Codon Capital:
Date
Company
Location
Round Details
Round Amount
Co-Investors
Jan 08, 2026
United States
Series B
4751
Nov 17, 2023
United States
Series B
1613
Sep 19, 2023
United States
Series A
2202
Jul 20, 2023
United States
Series A
6030
Nov 15, 2022
United States
Series A
7351

Unicorns in Codon Capital's Portfolio

Codon Capital has 1 unicorn in its portfolio - Pivot Bio. The most recent unicorn in their portfolio is Pivot Bio which became a unicorn in 2021, 1 years after Codon Capital first invested in it.
Here is a list of unicorns in Codon Capital's portfolio:
Tracxn Score
Company
Short Description
Founded year
Sector
Location
Company Stage
First Investment/ Acquisition Details
58
Developer of microbial nitrogen products designed for crop nutrition enhancement
2010
Berkeley
Series D
dspstug

IPOs and Publicly Listed companies in Codon Capital's Portfolio

7 of Codon Capital's portfolio companies have become public. Caribou Biosciences got listed on the National Association of Securities Dealers Automated Quotations (NASDAQ), in Jul 2021 at marketcap of $907M and Bolt Threads got listed on the National Association of Securities Dealers Automated Quotations (NASDAQ).
Here are Codon Capital's portfolio companies that went public:
Company
IPO Date
First Invested on
First Round of Investment
Round Size
Jul 23, 2021
-
-
2890
May 07, 2021
Apr 11, 2014
Series B
1148
Oct 09, 2020
-
-
7731
Apr 24, 2020
-
-
8304
Mar 15, 2018
-
-
3360

Acquired companies in Codon Capital's Portfolio

8 companies from Codon Capital's portfolio have been acquired. The most recent acquisition was RAPT in Jan 2026 by GSK for $*****.
Here are Codon Capital's portfolio companies that got acquired most recently:
Company
Acquisition Date
First Invested on
First Round of Investment
Round Size
Jan 20, 2026
-
-
6329
Sep 07, 2022
May 21, 2020
Series A
4832
Jul 25, 2022
-
-
3951
Apr 28, 2021
-
-
8989
Jul 17, 2018
-
-
5873

Co-investors of Codon Capital

Over the past 12 years, 83 investors have co-invested in Codon Capital's portfolio companies. This includes funds and angels.

Recent News related to Codon Capital

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