About R42 Group
R42 Group is a venture capital firm founded in 2004. It is primarily based out of Palo Alto, United States. As of May 2026, R42 Group is an active investor, having invested in 60 companies, with 3 new investments in the last 12 months. It primarily invests in Seed round in United Kingdom based startups. Its investments are spread across a wide range of sectors from Life Sciences to High Tech and Enterprise Applications. Most recently it participated in the $***** Seed round of Stamp Free Overall, R42 Group portfolio has seen 8 acquisitions including key companies like Cradlepoint, S2 Genomics and SQZBiotech. A lot of funds co-invest with R42 Group, with names like University of Cambridge sharing a substantial percentage of its portfolio. R42 Group has team of 8 people including 2 partners.Key Metrics
Team Members
Portfolio Count
Portfolio Sectors
Portfolio Locations
Rounds of Entry
Seed, Series A & 1 more
Portfolio Acquisitions
Deals in last 12 months
R42 Group's List of Top Investments
R42 Group has a portfolio of 60 companies. Their most notable investments are in Bounce Imaging and Oxford Drug Design.Their portfolio spans across United States, United Kingdom, Canada and 2 more locations. They have invested in Life Sciences, High Tech, Enterprise Applications and 20 other sectors, across stages such as Seed, Series A and 1 more. Here is the list of top investments by R42 Group:1. Cradlepoint
Provider of wireless wide area network and private cellular solutions. The company offers routers, adapters, and radios. It provides private and enterprise coverage solutions. Additionally, the company offers security access service edge.
Key facts about Cradlepoint
- Founded Year: 2004
- Location: Boise (United States)
- Last Known Valuation: $*****
- Stage: Acquired
- Total Funding till date: $155M
- Employee Count: 692 as on Mar 31, 2026
- Investors: Frazier VC, Delta-v Capital and 10 Others
- Latest Funding Round: Series C, Mar 09, 2017, $*****
- Highlight: Acquired
2. Healx
Provider of AI-powered drug discovery solutions for rare diseases. It helps identify new drug candidates, repurpose existing compounds, and accelerate rare disease research and development. The company combines machine learning, biomedical knowledge graphs, and expert drug discovery workflows to improve the speed and success rate of bringing treatments to patients.
Key facts about Healx
- Founded Year: 2014
- Location: Cambridge (United Kingdom)
- Annual Revenue: £0 - £1M as on Dec 31, 2022
- Valuation: $*****
- Stage: Series C
- Total Funding till date: $115M
- Employee Count: 70 as on Aug 31, 2026
- Investors: Atomico, Cambridge Angels and 19 Others
- Latest Funding Round: Series C, Aug 01, 2024, $*****
- Highlight: Editors' Pick
Developer of therapeutics for age-related diseases. The company uses propriety technology includes the ALEMBIC that focuses on developing medicines to combat biological aging by targeting pathologic cells like senescent ones that drive age-related diseases.
Key facts about RUBEDO LIFE SCIENCES
- Founded Year: 2018
- Location: Sunnyvale (United States)
- Stage: Series A
- Total Funding till date: $52M
- Employee Count: 32 as on Aug 31, 2026
- Investors: Ahren, The Longevity Fund and 13 Others
- Latest Funding Round: Series A, Apr 22, 2024, $*****
- Highlight: Editors' Pick
4. PayStand
Payment processing solutions for bitcoin, e-checks, and credit cards. It is a payment eCommerce checkout system that enables any organization to receive money from the website, social network, and web application without transaction costs. It is the first multi-payment gateway that accepts credit cards, ACH, Dwolla, and Bitcoins without transaction fees. Merchants pay a monthly fee for the payment software and avoid transaction fees charged by other payment services.
Key facts about PayStand
- Founded Year: 2013
- Location: San Francisco (United States)
- Valuation: $*****
- Stage: Series C
- Total Funding till date: $85M
- Employee Count: 236 as on May 31, 2026
- Investors: EPIC Ventures, NewView Capital and 22 Others
- Latest Funding Round: Series C, Jul 23, 2021, $*****
- Highlight: Editors' Pick
5. Hayden AI
Developer of mobile vision systems for automated traffic enforcement operations. These systems utilize vehicle-mounted hardware and artificial intelligence to monitor urban environments. The technology identifies parking and moving violations in transit lanes and bus stops to support traffic management. Data collected by these systems assists in maintaining clear transit corridors and improving the reliability of public transportation services.
Key facts about Hayden AI
- Founded Year: 2019
- Location: San Francisco (United States)
- Valuation: $*****
- Stage: Series C
- Total Funding till date: $193M
- Employee Count: 199 as on Aug 31, 2026
- Investors: The Rise Fund, London Technology Club and 21 Others
- Latest Funding Round: Series C, Jul 03, 2024, $*****
- Highlight: Editors' Pick
R42 Group's Year-on-Year Investment Trends
R42 Group has invested in 60 companies over the last 5 years, with an average of 3 new investments annually in the last 5 years. In 2025, it made 1 investment, while as of May 2026, it has made 3 investments in this year. Its most recent first time investment was in Stamp Free and most recent follow-on round was in xWatts.Year | No. of Investments | ||
|---|---|---|---|
1st Round | Follow-on | Total | |
2026 (YTD) | 2 | 1 | 3 |
2025 | 1 | 0 | 1 |
2024 | 3 | 2 | 5 |
2023 | 1 | 1 | 2 |
2022 | 7 | 1 | 8 |
2021 | 6 | 0 | 6 |
R42 Group's Investments by Stage
R42 Group has made 15 investments in Seed stage with an average round size of $3.9M, 4 investments in Series A stage with an average round size of $15.5M and 1 investment in Series C stage with an average round size of $47M.Stage of entry | No. of Investments |
|---|---|
Seed | 15 |
Series A | 4 |
Series C | 1 |
Note: We have considered here, only first round of investments
R42 Group's Investments by Sector
R42 Group has a diverse portfolio, with companies operating in the Life Sciences, Enterprise Applications, High Tech, Consumer and HealthTech. Notably, it has invested in 54 Tech companies, 53 Enterprise (B2B) companies, 28 Software companies and at least 20 companies focusing on Tech hardware.Sector | No. of Investments |
|---|---|
Life Sciences | 11 |
Enterprise Applications | 6 |
High Tech | 4 |
Consumer | 3 |
HealthTech | 3 |
Others | 14 |
Note: We have considered here, only first round of investments
R42 Group's Investments by Geography
R42 Group has made most investments in United Kingdom (12), followed by United States where it has made 6 investments.Country | No. of Investments |
|---|---|
United Kingdom | 12 |
United States | 6 |
Austria | 1 |
Switzerland | 1 |
Note: We have considered here, only first round of investments
R42 Group's recent investments
R42 Group has made 3 investments in 2026 so far. Stamp Free and xWatts are the latest among them.Here are the most recent investments by R42 Group:
Filter this listDate | Company | Location | Round Details | Round Amount | Co-Investors |
|---|---|---|---|---|---|
May 19, 2026 | United Kingdom | Seed | 9831 | - | |
Feb 10, 2026 | United Kingdom | Seed | 7111 | [+2] | |
Feb 2026 | United States | Seed | 9256 | [+2] | |
Nov 24, 2025 | United States | Seed | 6591 | [+5] | |
Oct 28, 2024 | United Kingdom | Series A | 8831 | [+3] |
Acquired companies in R42 Group's Portfolio
8 companies from R42 Group's portfolio have been acquired. The most recent acquisition was S2 Genomics.Here are R42 Group's portfolio companies that got acquired most recently:
Company | Acquisition Date | First Invested on | First Round of Investment | Round Size |
|---|---|---|---|---|
Sep 17, 2025 | - | - | 5600 | |
Feb 29, 2024 | - | - | 5167 | |
Jan 04, 2023 | - | - | 4045 | |
Nov 10, 2021 | - | - | 8274 | |
Sep 18, 2020 | - | - | 3495 |
Team profile of R42 Group
R42 Group has a team of 8 members including 2 Partners located in United States. R42 Group's team does not sit on the board of any company as of now.Co-investors of R42 Group
Over the past 5 years, 114 investors have co-invested in R42 Group's portfolio companies. This includes funds and angels.
- Invested before R42 Group: Khosla Ventures, o2h ventures and 32 others have invested in rounds before R42 Group. There are 2 companies where Khosla Ventures has invested before R42 Group and 2 companies where o2h ventures has invested before R42 Group.
- Top Co-investors of R42 Group: 59 investors entered a company along with R42 Group. These include investors like University of Cambridge (3 companies).
- Invested after R42 Group: A total of 21 investors have invested in R42 Group's portfolio after their investments. Top Investors include APEX Ventures (2 companies), M Ventures (1 company) and BioProcess360 (1 company).
Recent News related to R42 Group
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Oxford spin-out for AI-powered drug design hits crowdfunding targetInsider Media•Feb 03, 2026•o2h ventures, ACF Investors, R42 Group, Oxford Drug Design
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Cordance Medical Secures $8M Seed Funding for Brain Disease Treatment PlatformPR Newswire•Nov 24, 2025•PVTA, Cordance Medical, Angel Physicians Fund, SmartGateVC and 5 others
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capAI Forms Strategic AI Alliance with R42 GroupGlobal Legal Chronicle•Jun 03, 2025•capAI, R42 Group
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capAI partners with US AI venture capital firm, shares surge 23%Shareprices•May 27, 2025•R42 Group, capAI
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Abselion Raises £6.6M in Series A FundingFinSMEs•Dec 09, 2024•Abselion, M Ventures, BioProcess360, Untitled Ventures and 2 others
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Rare Disease Biotech Raises $47m Series C, Plans For Phase 2 Trial EndPoints News•Aug 01, 2024•Healx, R42 Group, Atomico, Balderton Capital and 6 others
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Cambridge-based xWatts secures $1.8M to slash energy costs by up to 40%Tech Funding News•Jul 18, 2024•xWatts, R42 Group, Parkwalk, Cambridge Enterprise and 1 other
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Italian Angels for Growth joins Rubedo €40m funding round with Khosla VenturesAngel News•May 03, 2024•RUBEDO LIFE SCIENCES, Khosla Ventures, Ahren, Hevolution and 8 others
