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About Unorthodox Ventures

Unorthodox Ventures, an accelerator and incubator program founded in 2017, is based in Austin, United States. With a presence in 6 countries, it has supported around 20 startups in sectors like Life Sciences, High Tech. As of Jul 2026, Unorthodox Ventures has witnessed 1 portfolio exit. Most notable companies in its portfolio include KEWAZO, Lumen and Vibrant. The program is backed by a team of 13 people who primarily support Seed startups based in United States. Its latest investment was a $120M Series E round in Supira Medical on Mar 25, 2025, which also saw participation from Novo Holdings and Qatar Investment Authority.
Key Metrics
Founded Year
2017
Location
Portfolio Companies
Sectors of Investment
Stages of Investment
Series B, Seed & 4 more
Locations of Investment

Unorthodox Ventures' List of Top Investments

Unorthodox Ventures has a portfolio of 20 companies. Their most notable investments are in Corporis Medical and Afia.Their portfolio spans across United States, Israel, Germany and 3 more locations. They have invested in Life Sciences, High Tech, HealthTech and 5 other sectors, across stages such as Series B, Seed  and 4 more. Here is the list of top investments by Unorthodox Ventures:
Provider of on-site robotics solutions for construction sites. It offers smart robotic elevators for scaffolding assembly processes at construction sites. Its features include analytic tools, automatic navigation, predictive analytics, and control tools. It caters to the construction, maritime, manufacturing, and transportation industries.

Key facts about KEWAZO

Provider of metabolism tracker for a diet plan. The device is breath monitoring-based and provides personalized data on the mobile app, for carbohydrates and fats to monitor the body metabolism and diet plan for weight loss and overall fitness.

Key facts about Lumen

Vibrant is a developer of chemical-free vibrating capsules for the treatment of constipation. The capsule induces vibration inside the GI tract mechanically induces peristalsis, thus aiding in treating constipated patients without side effects. It claims that the capsule targets the physiological parameters of constipation and induces natural bowel activity without using chemical supplements or changing the delicate internal body equilibrium.

Key facts about Vibrant

  • Founded Year: 2007
  • Location: Yokneam Illit (Israel)
  • Stage: Series E
  • Total Funding till date: $25M
  • Employee Count: 24 as on May 31, 2026
  • Investors: Tal Ventures, Precede Technologies and 3 Others
  • Latest Funding Round: Series E, Mar 25, 2021, $*****
  • Highlight: Editors' Pick
Provider of AI and cloud-based solutions for analyzing construction designs. Its platform enables users to run 3D designs and detect potential risks and errors. It leverages AI and identifies issues based on project data.

Key facts about Firmus

Developer of ventricular assist devices for coronary intervention and cardiogenic shock. The company has developed solutions for temporary mechanical circulatory support percutaneous ventricular assist devices. It has a feature that maintains the native pumping action of the heart. It provides real-time data about pump performance and location and minimizes vascular complications for patients with coronary artery disease.

Key facts about Supira Medical

Unorthodox Ventures' Investments by Stage

Unorthodox Ventures has made 6 investments in Series B stage with an average round size of $20.3M, 5 investments in Seed stage with an average round size of $1.7M and 5 investments in Series A stage with an average round size of $15.9M.
Here are Unorthodox Ventures' investments by stage:
Stage of entry
No. of Investments
Series B
6
Seed
5
Series A
5
Series C
2
Series D
1
Others
1
Breakdown of Unorthodox Ventures' investments by stage of entrySeries B (6)Seed (5)
Note: We have considered here, only first round of investments

Unorthodox Ventures' Investments by Sector

Unorthodox Ventures has a diverse portfolio, with companies operating in the Life Sciences, HealthTech, High Tech, Food and Agriculture and Internet of Things - Industry Applications. Notably, it has invested in 15 Tech companies, 13 Enterprise (B2B) companies, 13 Tech hardware companies and at least 4 companies focusing on Consumer (B2C).
Here are Unorthodox Ventures' investments by sector:
Sector
No. of Investments
Life Sciences
13
HealthTech
3
High Tech
3
Food and Agriculture
2
Internet of Things - Industry Applications
2
Others
7
Breakdown of Unorthodox Ventures' investments by sectorsLife Sciences (13)HealthTech (3)
Note: We have considered here, only first round of investments

Unorthodox Ventures' Investments by Geography

Unorthodox Ventures has made most investments in United States (11), followed by Israel where it has made 3 investments.
Here are Unorthodox Ventures' investments by geography:
Country
No. of Investments
United States
11
Israel
3
Germany
2
Switzerland
2
France
1
Others
1
Breakdown of Unorthodox Ventures' investments by countriesUnited States (11)Israel (3)
Note: We have considered here, only first round of investments

Unorthodox Ventures' recent investments

Unorthodox Ventures has not made any investment in 2026 so far.
Here are the most recent investments by Unorthodox Ventures:
Date
Company
Location
Round Details
Round Amount
Co-Investors
Mar 25, 2025
United States
Series E
9043
Feb 12, 2025
United States
Series C
6861
Oct 24, 2024
United States
Series A
9379
Sep 10, 2024
Switzerland
Series B
9231
Jun 27, 2024
United States
Series C
9906

Acquired companies in Unorthodox Ventures' Portfolio

1 company from Unorthodox Ventures' portfolio has been acquired. The most recent acquisition was Firmus in Sep 2025 by Nemetschek Group for $*****.
Here are Unorthodox Ventures' portfolio companies that got acquired most recently:
Company
Acquisition Date
First Invested on
First Round of Investment
Round Size
Sep 04, 2025
May 15, 2024
Seed
1986

Team profile of Unorthodox Ventures

Unorthodox Ventures has a team of 13 members including 2 Partners and 8 Principals located in United States. Unorthodox Ventures' team does not sit on the board of any company as of now.
Here is a list of top team members in Unorthodox Ventures:
Name
Designation
Location
Board Memberships
Contact Details
Partner
Austin
-
Partner
United States
-
Principal
Austin
-
Principal
Austin
-
Principal
New York City
-
Principal
-
-
-
Principal
Austin
-
Principal
United States
-
Principal
United States
-
Principal
-
-

Co-investors of Unorthodox Ventures

Over the past 7 years, 118 investors have co-invested in Unorthodox Ventures's portfolio companies. This includes funds and angels.

  • Invested before Unorthodox VenturesThe Capital Partnership, Shifamed and 59 others have invested in rounds before Unorthodox Ventures. There are 3 companies where The Capital Partnership has invested before Unorthodox Ventures and 3 companies where Shifamed has invested before Unorthodox Ventures.
  • Top Co-investors of Unorthodox Ventures39 investors entered a company along with Unorthodox Ventures. These include investors like PA MedTech VC Fund (2 companies).
  • Invested after Unorthodox VenturesA total of 18 investors have invested in Unorthodox Ventures's portfolio after their investments. Top Investors include Schooner Capital (1 company) and Chevron Technology Ventures (1 company).

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