About Unorthodox Ventures
Unorthodox Ventures, an accelerator and incubator program founded in 2017, is based in Austin, United States. With a presence in 6 countries, it has supported around 20 startups in sectors like Life Sciences, High Tech. As of May 2026, Unorthodox Ventures has witnessed 1 portfolio exit. Most notable companies in
its portfolio include Adona Medical, KEWAZO and Lumen. The program is backed by a team of 15 people who primarily support Seed startups based in United States. Its latest investment was a $120M Series E round in Supira Medical on Mar 25, 2025, which also saw participation from Novo Holdings and Qatar Investment Authority.
Key Metrics
Founded Year
2017
Location
Austin, United States
Portfolio Companies
Sectors of Investment
Stages of Investment
Series B, Seed & 4 more
Locations of Investment
Unorthodox Ventures' List of Top Investments
Unorthodox Ventures has a portfolio of 20 companies. Their most notable investments are in Corporis Medical and Afia.Their portfolio spans across United States, Israel, Germany and 3 more locations. They have invested in Life Sciences, High Tech, HealthTech and 5 other sectors, across stages such as Series B, Seed and 4 more. Here is the list of top investments by Unorthodox Ventures:Developer of medical devices for the management of heart failure. It is developing next-generation of interatrial shunting and hemodynamic sensors to address patients with heart failure.
Key facts about Adona Medical
- Founded Year: 2017
- Location: Campbell (United States)
- Stage: Series C
- Total Funding till date: $71M
- Employee Count: 33 as on Mar 31, 2026
- Investors: Cormorant Asset Management, Shifamed and 7 Others
- Latest Funding Round: Series C, Jun 27, 2024, $*****
- Highlight: Editors' Pick
2. KEWAZO
Provider of on-site robotics solutions for construction sites. It offers smart robotic elevators for scaffolding assembly processes at construction sites. Its features include analytic tools, automatic navigation, predictive analytics, and control tools. It caters to the construction, maritime, manufacturing, and transportation industries.
Key facts about KEWAZO
- Founded Year: 2016
- Location: Garching (Germany)
- Stage: Series A
- Total Funding till date: $35M
- Employee Count: 50 as on Mar 31, 2026
- Investors: Fifth Wall, Chevron Technology Ventures and 18 Others
- Latest Funding Round: Series A, Mar 19, 2026, $*****
- Highlight: Editors' Pick
3. Lumen
Provider of metabolism tracker for a diet plan. The device is breath monitoring-based and provides personalized data on the mobile app, for carbohydrates and fats to monitor the body metabolism and diet plan for weight loss and overall fitness.
Key facts about Lumen
- Founded Year: 2014
- Location: Ramat Hasharon (Israel)
- Stage: Series B
- Total Funding till date: $77.5M
- Employee Count: 318 as on Mar 31, 2026
- Investors: Red Swan, BNSG Capital and 18 Others
- Latest Funding Round: Series B, Dec 01, 2022, $*****
- Highlight: Editors' Pick
4. Vibrant
Vibrant is a developer of chemical-free vibrating capsules for the treatment of constipation. The capsule induces vibration inside the GI tract mechanically induces peristalsis, thus aiding in treating constipated patients without side effects. It claims that the capsule targets the physiological parameters of constipation and induces natural bowel activity without using chemical supplements or changing the delicate internal body equilibrium.
Key facts about Vibrant
- Founded Year: 2007
- Location: Yokneam Illit (Israel)
- Stage: Series E
- Total Funding till date: $25M
- Employee Count: 25 as on Mar 31, 2026
- Investors: Sequoia Capital, Tal Ventures and 3 Others
- Latest Funding Round: Series E, Mar 25, 2021, $*****
- Highlight: Editors' Pick

5. Firmus
Provider of AI and cloud-based solutions for analyzing construction designs. Its platform enables users to run 3D designs and detect potential risks and errors. It leverages AI and identifies issues based on project data.
Key facts about Firmus
- Founded Year: 2019
- Location: Herzliya (Israel)
- Stage: Acquired
- Total Funding till date: $150K
- Employee Count: 37 as on Mar 31, 2026
- Investors: Navitas Capital, Third Sphere and 7 Others
- Latest Funding Round: Seed, May 15, 2024, $*****
- Highlight: Acquired
Unorthodox Ventures' Year-on-Year Investment Trends
Unorthodox Ventures has invested in 21 companies over the last 7 years, with an average of 3 new investments annually in the last 5 years. In 2025, it made 2 investments. Its most recent first time investment was in Laplace Interventional and most recent follow-on round was in Supira Medical.Year | No. of Investments | ||
|---|---|---|---|
1st Round | Follow-on | Total | |
2026 (YTD) | 0 | 0 | 0 |
2025 | 1 | 1 | 2 |
2024 | 5 | 0 | 5 |
2023 | 6 | 0 | 6 |
2022 | 3 | 1 | 4 |
2021 | 2 | 0 | 2 |
2020 | 1 | 0 | 1 |
2019 | 2 | 0 | 2 |
Unorthodox Ventures' Investments by Stage
Unorthodox Ventures has made 6 investments in Series B stage with an average round size of $20.3M, 5 investments in Seed stage with an average round size of $1.7M and 5 investments in Series A stage with an average round size of $15.9M.Stage of entry | No. of Investments |
|---|---|
Series B | 6 |
Seed | 5 |
Series A | 5 |
Series C | 2 |
Series D | 1 |
Others | 1 |
Note: We have considered here, only first round of investments
Unorthodox Ventures' Investments by Sector
Unorthodox Ventures has a diverse portfolio, with companies operating in the Life Sciences, HealthTech, High Tech, Food and Agriculture and Internet of Things - Industry Applications. Notably, it has invested in 15 Tech companies, 13 Enterprise (B2B) companies, 13 Tech hardware companies and at least 4 companies focusing on Consumer (B2C).Sector | No. of Investments |
|---|---|
Life Sciences | 13 |
HealthTech | 3 |
High Tech | 3 |
Food and Agriculture | 2 |
Internet of Things - Industry Applications | 2 |
Others | 7 |
Note: We have considered here, only first round of investments
Unorthodox Ventures' Investments by Geography
Unorthodox Ventures has made most investments in United States (11), followed by Israel where it has made 3 investments.Country | No. of Investments |
|---|---|
United States | 11 |
Israel | 3 |
Germany | 2 |
Switzerland | 2 |
France | 1 |
Others | 1 |
Note: We have considered here, only first round of investments
Unorthodox Ventures' recent investments
Unorthodox Ventures has not made any investment in 2026 so far.Here are the most recent investments by Unorthodox Ventures:
Date | Company | Location | Round Details | Round Amount | Co-Investors |
|---|---|---|---|---|---|
Mar 25, 2025 | United States | Series E | 3763 | [+6] | |
Feb 12, 2025 | United States | Series C | 1430 | [+3] | |
Oct 24, 2024 | United States | Series A | 3110 | [+4] | |
Sep 10, 2024 | Switzerland | Series B | 8451 | [+8] | |
Jun 27, 2024 | United States | Series C | 7102 | [+4] |
Acquired companies in Unorthodox Ventures' Portfolio
1 company from Unorthodox Ventures' portfolio has been acquired. The most recent acquisition was Firmus in Sep 2025 by Nemetschek Group for $*****.Here are Unorthodox Ventures' portfolio companies that got acquired most recently:
Company | Acquisition Date | First Invested on | First Round of Investment | Round Size |
|---|---|---|---|---|
Sep 04, 2025 | May 15, 2024 | Seed | 2161 |
Team profile of Unorthodox Ventures
Unorthodox Ventures has a team of 15 members including 2 Partners and 8 Principals located in United States. Unorthodox Ventures' team does not sit on the board of any company as of now.Here is a list of top team members in Unorthodox Ventures:
Name | Designation | Location | Board Memberships | Contact Details |
|---|---|---|---|---|
Partner | Austin | - | ||
Partner | United States | - | ||
Principal | Austin | - | ||
Principal | Austin | - | ||
Principal | New York City | - | ||
Principal | - | - | - | |
Principal | Austin | - | ||
Principal | United States | - | ||
Principal | United States | - | ||
Principal | - | - |
Co-investors of Unorthodox Ventures
Over the past 7 years, 118 investors have co-invested in Unorthodox Ventures's portfolio companies. This includes funds and angels.
- Invested before Unorthodox Ventures: Shifamed, The Capital Partnership and 59 others have invested in rounds before Unorthodox Ventures. There are 3 companies where Shifamed has invested before Unorthodox Ventures and 3 companies where The Capital Partnership has invested before Unorthodox Ventures.
- Top Co-investors of Unorthodox Ventures: 39 investors entered a company along with Unorthodox Ventures. These include investors like PA MedTech VC Fund (2 companies).
- Invested after Unorthodox Ventures: A total of 18 investors have invested in Unorthodox Ventures's portfolio after their investments. Top Investors include Schooner Capital (1 company) and Chevron Technology Ventures (1 company).
Recent News related to Unorthodox Ventures
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Supira Medical raises $120M in Series E funding, completes US feasibility study.PR Newswire•Mar 26, 2025•Supira Medical, Novo Holdings, Sidley, Piper Sandler and 7 others
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Laplace Interventional Raises $22M in Series C FundingFinSMEs•Mar 17, 2025•Laplace Interventional, Aphelion Capital, Engage, Unorthodox Ventures and 2 others
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Laplace: $22 Million Raised For Transcatheter Tricuspid Valve TechnologyPulse 2.0•Mar 17, 2025•Laplace Interventional, Aphelion Capital, Engage, Unorthodox Ventures and 2 others
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Laplace raises funding to complete study of tricuspid valve technologyMedicalDeviceNetwork•Mar 17, 2025•Laplace Interventional, Unorthodox Ventures, Aphelion Capital
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Sonavex secures $15m in Series A-2 funding roundMedicalDeviceNetwork•Oct 25, 2024•Sonavex, Unorthodox Ventures, GenHenn Capital, JSTAR and 3 others
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CorFlow Therapeutics AG Completes €44 Million Series B Financing to Support the Advancement of a Novel Diagnostic and Drug Delivery Platform for Microvascular Obstruction (MVO) in Heart Attack PatientsFinancial Post•Sep 10, 2024•Corflow, Broadview Ventures, Panakes Partners, 415 CAPITAL and 9 others
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Adona Medica Raises $33.5M in Series C FinancingFinSMEs•Jul 10, 2024•Adona Medical, Cormorant Asset Management, TCP Venture Capital, Excelestar Ventures and 6 others
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ConKay Medical Systems Raises $1.8 Million in Seed FundingMedical Product Outsourcing•May 02, 2024•ConKay Medical Systems, Unorthodox Ventures, SCP Ventures
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Shifamed's Laza Medical closes $36M Series AMassDevice•Dec 12, 2023•Shifamed, The Capital Partnership, GE HealthCare, Unorthodox Ventures and 4 others
