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Debut - About the company

Debut is a series B company based in San Diego (United States), founded in 2019 by Joshua Britton and Gregory Weiss. It operates as a Provider and manufacturer of enzymes for biotherapeutic creation and modification. Debut has raised $126M in funding from investors like BOLD, INX International Ink and KdT Ventures, with a current valuation of $*****. The company has 92 active competitors, including 17 funded and 16 that have exited. Its top competitors include companies like Codexis, EnginZyme and Immobazyme.

Company Details

Provider and manufacturer of enzymes for biotherapeutic creation and modification. The company offers a range of enzymes that are used in the biotech industry for immobilization and other therapeutic applications. The company also provides continuous biomanufacturing cartridges, immobilized cells, immobilized enzymes for continuous biomanufacturing.
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Email ID
*****@debutbiotech.com
Registered Address
86-90 PAUL STREET,LONDON,ENGLAND,EC2A 4NE
Key Metrics
Founded Year
2019
Location
San Diego, United States
Stage
Series B
Total Funding
$126M in 8 rounds
Latest Funding Round
Post Money Valuation
$***** as on Mar 03, 2023
Investors
Ranked
Employee Count
96 as on Sep 30, 2026
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Debut's funding and investors

Debut has raised a total funding of $126M over 8 rounds. Its first funding round was on Jan 06, 2020. Its latest funding round was a Series B round on Aug 26, 2025 for $*****. 6 investors participated in its latest round. Debut has 18 institutional investors.

Here is the list of recent funding rounds of Debut:lockFilter this list
Date of Funding
Funding Amount
Round Name
Post-Money Valuation
Revenue Multiple
Lead Investors
Other Investors
Aug 26, 2025
4529151
Series B
4685986
6235352
4266779
2647559
Oct 19, 2023
4166137
Series B
3068481
2680695
1275927
9019751
Jun 12, 2023
2539245
Series B
5049122
7273165
8486714
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Debut's founders and board of directors

Founder? Claim Profile
The founders of Debut are Joshua Britton and Gregory Weiss. Joshua Britton is the CEO of Debut.
Here are the details of Debut's key team members:

Debut's Board of Directors

Debut's board has 5 active members. Joshua Britton, Daniel Phillips, Cain A. McClary, CORINNA CHEN and GREGORY A. WEISS are independent board members.
Here is the list of Debut's board of directors:
Name
Type
Representing
Status
Duration
Independent board member
-
Current
6y 8m
wtguys{
Independent board member
-
Current
5y 6m
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Independent board member
-
Current
1y 9m
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Independent board member
-
Current
9y 9m
rflpycb
Independent board member
-
Current
5y 9m

Debut's employee count trend

Debut has 96 employees as of Sep 26. Here is Debut's employee count trend over the years:
Employee count trend for Debut
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Debut's Competitors and alternates

Top competitors of Debut include Codexis, EnginZyme and Immobazyme. Here is the list of Top 10 competitors of Debut, ranked by Tracxn score:
Rank
Company Details
Short Description
Total Funding
Investors
Tracxn Score
1st
Logo for Codexis
Codexis
2002, Redwood City (United States), Public
Developer of high-performance enzymes for drug discovery
$111M
68/100
2nd
Logo for EnginZyme
EnginZyme
2014, Stockholm (Sweden), Series B
Developer of immobilized enzymes
$42.3M
57/100
3rd
Logo for Immobazyme
Immobazyme
2019, Stellenbosch (South Africa), Series A
Developer of enzyme immobilisation technology
$2.9M
51/100
4th
Logo for Debut
Debut
2019, San Diego (United States), Series B
Provider and manufacturer of enzymes for biotherapeutic creation and modification
$126M
52/100
5th
Logo for Genovis
Genovis
1999, Lund (Sweden), Public
Develps enzymes for antibodies
-
50/100
6th
Logo for Allozymes
Allozymes
2019, Singapore (Singapore), Series A
Developer of enzyme engineering platform for biosolutions across diverse industries
$20M
48/100
7th
Logo for Twelve Bio
Twelve Bio
2019, Copenhagen (Denmark), Acquired
Developer of CRISPER technology based diagnostics and therapeutics
$2.57M
45/100
8th
Logo for Nucleus Biologics
Nucleus Biologics
2016, San Diego (United States), Funding Raised
Cell culture solutions provider accelerating cell and gene therapy development
-
-
43/100
9th
Logo for New England Biolabs
New England Biolabs
1970, Ipswich (United Kingdom), Funding Raised
Molecular biology reagents company
-
43/100
10th
Logo for Creative Enzymes
Creative Enzymes
2011, New York City (United States), Unfunded
Enzymes, probiotics, and extracts for research, diagnostics, and industrial applications
-
-
41/100
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Debut's Investments and acquisitions

Debut has made no investments or acquisitions yet.

Reports related to Debut

Here is the latest report on Debut's sector:

News related to Debut

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FAQs about Debut

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