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Generation Bio - About the company

Generation Bio is an acquired company based in Cambridge (United States), founded in 2016 by Mark Angelino, Robert M Kotin and Phillip Samayoa. It operates as a Developer of gene therapies for rare liver and eye diseases. Generation Bio has raised $236M in funding from Fidelity Investments and T. Rowe Price, with last known valuation of $*****. The company has 789 active competitors, including 271 funded and 219 that have exited. Its top competitors include companies like Moderna, BridgeBio and Spark Therapeutics.

Company Details

Developer of gene therapies for rare liver and eye diseases. The company provides non-viral gene therapies for phenylketonuria, hemophilia A, Wilson disease, Leber congenital amaurosis, Stargardt disease, and others. The Gene Wave technology is used for optimal titration and can also be re-dosed by using closed-ended DNA for gene therapy development. The ceDNA is packaged in a lipid nanoparticle that dissolves into the cytoplasm of a cell and heads to the nucleus to produce proteins.
Social
X
Email ID
*****@generationbio.com, *****@generationbio.com
Registered Address
Cambridge, Massachusetts
Key Metrics
Founded Year
2016
Location
Cambridge, United States
Stage
Acquired
Total Funding
$236M in 3 rounds
Latest Funding Round
Last Known Valuation
$***** as on Dec 15, 2025
Ranked
Annual Revenue
$19.9M as on Dec 31, 2024
Employee Count
45 as on Mar 31, 2026
Similar Companies
Exit Details
Acquired by XOMA Corporation (Dec 15, 2025)

Generation Bio's acquisition details

Generation Bio got acquired by XOMA Corporation on Dec 15, 2025.
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Generation Bio's funding and investors

Generation Bio has raised a total funding of $236M over 3 rounds. Its first funding round was on Jan 04, 2018. Its latest funding round was a Series C round on Jan 10, 2020 for $*****. 10 investors participated in its latest round. Generation Bio has 11 institutional investors.

Here is the list of recent funding rounds of Generation Bio:
Date of Funding
Funding Amount
Round Name
Post-Money Valuation
Revenue Multiple
Lead Investors
Other Investors
Jan 10, 2020
5543943
Series C
8349597
3813363
5903486
1570612
Feb 27, 2018
5189183
Series B
4813342
8167376
3848192
Jan 04, 2018
5760671
Series A
1373679
4509315
6023191
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Generation Bio's founders and board of directors

Founder? Claim Profile
The founders of Generation Bio are Mark Angelino, Robert M Kotin and Phillip Samayoa. Geoff McDonough is the CEO of Generation Bio.
Here are the details of Generation Bio's key team members:

Generation Bio's employee count trend

Generation Bio has 45 employees as of Mar 26. Here is Generation Bio's employee count trend over the years:
Employee count trend for Generation Bio
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Generation Bio's Competitors and alternates

Top competitors of Generation Bio include Moderna, BridgeBio and Spark Therapeutics. Here is the list of Top 10 competitors of Generation Bio, ranked by Tracxn score:
Rank
Company Details
Short Description
Total Funding
Investors
Tracxn Score
1st
Logo for Moderna
Moderna
2010, Cambridge (United States), Public
Developer of mRNA-based therapeutics for a wide range of diseases
$2.78B
81/100
2nd
Logo for BridgeBio
BridgeBio
2015, Palo Alto (United States), Acquired
Developer of therapeutics for the treatment of genetic diseases
$434M
75/100
3rd
Logo for Spark Therapeutics
Spark Therapeutics
2013, Philadelphia (United States), Acquired
Developer of gene therapy for rare diseases
$82.8M
75/100
4th
Logo for Exact Sciences
Exact Sciences
1995, Madison (United States), Public
Provider of non-invasive molecular diagnostic testing solutions for cancer
-
73/100
5th
Logo for Forge Biologics
Forge Biologics
2020, Columbus (United States), Acquired
Developer of gene therapeutic solutions for treating multiple diseases
$330M
72/100
6th
Developer of peptide therapeutics for the treatment of rare genetic deficiencies
$84M
72/100
7th
Logo for Fulcrum Therapeutics
Fulcrum Therapeutics
2015, Cambridge (United States), Public
Developing small molecules for control mechanisms and genes regulation for the treatment of rare diseases
$115M
72/100
8th
Logo for Strand Therapeutics
Strand Therapeutics
2017, Cambridge (United States), Series B
Provider of platform to deliver mRNA therapeutics for multi functional treatments
$256M
72/100
9th
Logo for Insitro
Insitro
2018, San Francisco (United States), Series C
Developer of an AI-enabled technology platform for the treatment of infectious disease
$643M
72/100
10th
Logo for Alnylam
Alnylam
2002, Cambridge (United States), Public
Developer of RNA interference-based therapeutics for multiple disorders
$17M
71/100
12th
Logo for Generation Bio
Generation Bio
2016, Cambridge (United States), Acquired
Developer of gene therapies for rare liver and eye diseases
$236M
69/100
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Generation Bio's Investments and acquisitions

Generation Bio has made no investments or acquisitions yet.

Reports related to Generation Bio

Here is the latest report on Generation Bio's sector:

News related to Generation Bio

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Media has covered Generation Bio for a total of 8 events in the last 1 year, 1 of them has been about people movement.
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