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About K2 HealthVentures

K2 HealthVentures, established in 2018, is a private debt fund primarily based in Boston, United States. It specializes in financing Conventional Debt round of companies based in United States. Its portfolio includes 43 firms, spanning the Life Sciences, HealthTech sectors.
As of Aug 2026, K2 HealthVentures has 3 unicorns under its belt and has witnessed 18 portfolio exits so far. Its most notable investments include companies like TScan Therapeutics, Alto Neuroscience and DispatchHealth.
Its latest investment was a $53M Series D round in Hopscotch Health on Aug 18, 2026, which also saw participation from 8VC and Town Hall Ventures.
Key Metrics
Founded Year
2018
Location
Sectors of Investment
Stages of Investment
Conventional Debt, Series D & 7 more
Locations of Investment
Unicorn in Portfolio

K2 HealthVentures' List of Top Investments

K2 HealthVentures has a portfolio of 43 companies, including 3 unicorns. Their most notable investments include TScan Therapeutics and Alto Neuroscience.Their portfolio spans across United States, Ireland, Singapore and 1 more locations. They have invested in Life Sciences, HealthTech, Enterprise Applications and 7 other sectors, across stages such as Conventional Debt, Series D  and 7 more. Here is the list of top investments by K2 HealthVentures:
Developer of T cell therapies to harness the immune system against cancer. The company focuses on hematologic malignancies and solid tumors using proprietary platforms like TargetScan and ReceptorScan. The company's product line include TSC-100 and TSC-101 target residual disease in AML, MDS, and ALL patients post-allogeneic hematopoietic cell transplant.

Key facts about TScan Therapeutics

AI-driven drug discovery platform for neurological diseases based on patients biomarkers. The company's platform measures patients biomarkers like EEG and wearable data, behavioral patterns, genetics, and other factors to develop personalized psychiatric drugs. The company has pipeline of drugs including ALTO-100 for depression, ALTO-101 for neurodegenerative diseases, and more.

Key facts about Alto Neuroscience

Provider of on-demand physician visits at home. The platform provides access to users to request physicians visit based on symptoms and conditions. It offers prescription delivery with insurance claims. The platform offers treatments for multiple health conditions.

Key facts about DispatchHealth

Developer of mineral-based sunscreens and clinical skincare products. It offers a range of sunscreens, treatments, serums, and cosmetics formulated with natural minerals and botanicals. The company focuses on providing effective sun protection and skin health improvement through clinically tested products. Product lines include mineral sunscreens, skincare treatments addressing concerns like aging and hyperpigmentation, and mineral-based cosmetics. A skin quiz is available to assist customers in selecting personalized skincare regimens.

Key facts about Colorescience

Provider of mobile apps for treatment of brain disorders. It offers solutions to treat people with brain disorders and neuro psychiatric dysfunction. The platform enables patients to input daily activity and aims for behavior and cognitive modification, by connecting with the care team. The mobile apps are focused on smoking and cessation, Alzheimers, ADHD, and TBI.

Key facts about Click Therapeutics

K2 HealthVentures' Investments by Stage

K2 HealthVentures has made 10 investments in Conventional Debt stage with an average round size of $49.8M, 3 investments in Series D stage with an average round size of $108M and 2 investments in Post IPO stage with an average round size of $22.5M.
Here are K2 HealthVentures' investments by stage:
Stage of entry
No. of Investments
Conventional Debt
10
Series D
3
Post IPO
2
Series B
2
Venture Debt
2
Others
4
Breakdown of K2 HealthVentures' investments by stage of entryConventional Debt (10)Series D (3)
Note: We have considered here, only first round of investments

K2 HealthVentures' Investments by Sector

K2 HealthVentures has a diverse portfolio, with companies operating in the Life Sciences, HealthTech, Healthcare, Enterprise Applications and Consumer. Notably, it has invested in 32 Tech companies, 28 Enterprise (B2B) companies, 8 Software companies and at least 7 companies focusing on Consumer (B2C).
Here are K2 HealthVentures' investments by sector:
Sector
No. of Investments
Life Sciences
9
HealthTech
7
Healthcare
5
Enterprise Applications
4
Consumer
3
Others
8
Breakdown of K2 HealthVentures' investments by sectorsLife Sciences (9)HealthTech (7)
Note: We have considered here, only first round of investments

K2 HealthVentures' Investments by Geography

K2 HealthVentures has made most investments in United States (21), followed by Singapore where it has made 1 investment.
Here are K2 HealthVentures' investments by geography:
Country
No. of Investments
United States
21
Singapore
1
Breakdown of K2 HealthVentures' investments by countriesUnited States (21)Singapore (1)
Note: We have considered here, only first round of investments

K2 HealthVentures' recent investments

K2 HealthVentures has made 5 investments in 2026 so far. Hopscotch Health and Mighty Therapeutics are the latest among them.
Here are the most recent investments by K2 HealthVentures:
Date
Company
Location
Round Details
Round Amount
Co-Investors
Aug 18, 2026
United States
Series D
2683
  [+7]
Jul 14, 2026
United States
Conventional Debt
6156
-
Feb 26, 2026
United States
Series D
1213
  [+4]
Jan 21, 2026
-
Series A
2157
Jan 08, 2026
United States
Series B
6644

Unicorns in K2 HealthVentures' Portfolio

K2 HealthVentures has 3 unicorns in its portfolio - DispatchHealth, LetsGetChecked and Inari. The most recent unicorn in their portfolio is DispatchHealth. It became a unicorn in 2022.
Here is a list of unicorns in K2 HealthVentures' portfolio:
Tracxn Score
Company
Short Description
Founded year
Sector
Location
Company Stage
First Investment/ Acquisition Details
65
Provider of on-demand physician visits at home
2013
Denver
Series D
{rnksjp
56
Online platform to order at home diagnostic tests for all health conditions
2013
Dublin
Series D
vyxyptt
64
Developer of technology to improve crop breeding and seed production
2016
Cambridge
Series G
zlvvgwz

IPOs and Publicly Listed companies in K2 HealthVentures' Portfolio

11 of K2 HealthVentures' portfolio companies have become public. Alto Neuroscience got listed on the New York Stock Exchange (NYSE), in Feb 2024 at marketcap of $409M and TScan Therapeutics got listed on the National Association of Securities Dealers Automated Quotations (NASDAQ) at marketcap of $359M.
Here are K2 HealthVentures' portfolio companies that went public:
Company
IPO Date
First Invested on
First Round of Investment
Round Size
Feb 02, 2024
Jan 30, 2023
Venture Debt
2022
Jul 16, 2021
-
-
9133
Jun 25, 2021
-
-
4631
Apr 27, 2021
-
-
3594
Mar 26, 2021
-
-
1205

Acquired companies in K2 HealthVentures' Portfolio

7 companies from K2 HealthVentures' portfolio have been acquired. The most recent acquisition was 89bio in Sep 2025 by Roche for $*****.
Here are K2 HealthVentures' portfolio companies that got acquired most recently:
Company
Acquisition Date
First Invested on
First Round of Investment
Round Size
Sep 17, 2025
-
-
1986
May 16, 2025
-
-
2583
Jan 08, 2024
Mar 28, 2023
Post IPO
6217
Jun 16, 2023
-
-
3975
Aug 12, 2020
Jan 10, 2020
Conventional Debt
7046

Team profile of K2 HealthVentures

K2 HealthVentures has a team of 11 members including 2 Partners and 2 Principals located in United States.
Here is a list of top team members in K2 HealthVentures:
Name
Designation
Location
Contact Details
Partner
Miami
-
Partner
Chicago
Principal
New York City
Principal
New York City

Co-investors of K2 HealthVentures

Over the past 7 years, 257 investors have co-invested in K2 HealthVentures's portfolio companies. This includes funds and angels.

  • Invested before K2 HealthVenturesHHS, Oak HC/FT and 163 others have invested in rounds before K2 HealthVentures. There are 3 companies where HHS has invested before K2 HealthVentures and 3 companies where Oak HC/FT has invested before K2 HealthVentures.
  • Top Co-investors of K2 HealthVentures49 investors entered a company along with K2 HealthVentures. These include investors like Rubicon Founders (3 companies).
  • Invested after K2 HealthVenturesA total of 43 investors have invested in K2 HealthVentures's portfolio after their investments. Top Investors include Alexandria (2 companies) and Commodore Capital (2 companies).

Recent News related to K2 HealthVentures

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FAQs about K2 HealthVentures

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