About Gene Therapy
There are 636 companies in the Gene Therapy sector across the world, with 472 funded companies having collectively raised $34.9B in venture capital money and private equity. Overall 276 of these are Series A+ funded, and 1 of these is a unicorn.
Gene Therapy sector has seen 76 acquisitions and 62 IPOs. This represents almost 21.7% of all such companies - which is higher than the 4.9% exit rate of tech companies in general.
This sector includes companies developing gene therapies to treat diseases in humans.
Companies included in Gene Therapy sector
Companies developing RNA, DNA and PNA based therapies for the treatment of various diseases.Companies excluded in Gene Therapy sector
Companies developing drugs or therapeutics for animal healthcare Companies that provide digital solutions like an app, software, web portals for the management/treatment of diseases. Companies developing therapies other than gene therapy for the treatment of diseases.Market Map of Gene Therapy
The market map of Gene Therapy gives a visual overview of the sector, showing key business models, their interactions in the value chain, and industry evolution. Trending business models in Gene Therapy sector are Viral Vector Gene Therapy and mRNA Therapeutics.
Reports related to Gene Therapy
Here is a report related to Gene Therapy sector:
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There are more than 636 companies in Gene Therapy. Moderna is the top Gene Therapy company globally, ranked using Tracxn Score (what's this?).
Here are 5 of the top Gene Therapy companies globally:
Company | Description | Location | Founded | Current Stage | Private Funding Raised |
|---|---|---|---|---|---|
Developer of mRNA-based therapeutics for a wide range of diseases | Cambridge (United States) | 2010 | Public | $2.78B | |
Developer of gene therapy for rare diseases | Philadelphia (United States) | 2013 | Acquired | $82.8M | |
Developer of RNA interference-based therapeutics for multiple disorders | Cambridge (United States) | 2002 | Public | $17M | |
Developer of gene-based therapies for patients with genetic or acquired diseases | Amsterdam (Netherlands) | 1998 | Public | $111M | |
Provider of platform to deliver mRNA therapeutics for multi functional treatments | Cambridge (United States) | 2017 | Series B | $256M |
Companies founded year-on-year in the Gene Therapy sector
62 Gene Therapy startups were founded in 2021 - this is the most number of startups founded in any year in the last 10 years.
- Total Number of Companies
Year | No. of companies |
|---|---|
2026 | - |
2025 | 1 |
2024 | 10 |
2023 | 12 |
2022 | 32 |
2021 | 62 |
2020 | 53 |
2019 | 58 |
2018 | 32 |
2017 | 32 |
Companies founded across countries in the Gene Therapy sector
United States has 352 Gene Therapy startups, the most by any country, followed by United Kingdom which has 42 startups and China which has 34.
- Total Number of Companies
Country | No. of companies |
|---|---|
United States | 352 |
United Kingdom | 42 |
China | 34 |
South Korea | 26 |
France | 21 |
Germany | 21 |
Canada | 18 |
Netherlands | 15 |
Japan | 12 |
Spain | 11 |
Stage-wise distribution of the Gene Therapy sector
Out of the total 636 Gene Therapy companies, 472 have secured funding. Among them, 276 have reached Series A or higher, and 201 to Series B or beyond.
Founded - 636
Funded - 472
Series A+ - 276
Series B+ - 201
Series C+ - 156
Company Stage | No. of companies |
|---|---|
Founded | 636 |
Funded | 472 |
Series A+ | 276 |
Series B+ | 201 |
Series C+ | 156 |
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- 635+ Total Companies
- $34.9B+ Total Funding
- 470+ Funded Companies
- 60+ IPOs
- 75+ Acquisitions
Funding Trends in the Gene Therapy sector
Total funding year-on-year in the Gene Therapy sector
The Gene Therapy sector saw a total funding of more than $25.6B in the last 10 years. The most amount of funding was in 2021 at more than $5.15B. There has been a total funding of $437M in 2026 till date.
- Total Funding
Year | Total Funding |
|---|---|
2026 | $437M |
2025 | $2.55B |
2024 | $2.35B |
2023 | $1.7B |
2022 | $2.27B |
2021 | $5.15B |
2020 | $4.61B |
2019 | $2.01B |
2018 | $2.43B |
2017 | $2.05B |
Total funding across countries in the Gene Therapy sector
In the last 10 years, Gene Therapy startups in United States have recieved the highest funding among all countries - $16.8B. United Kingdom follows with $2.49B and Germany with $1.3B.
- Total Funding
Country | Total Funding |
|---|---|
United States | $16.8B |
United Kingdom | $2.49B |
Germany | $1.3B |
Switzerland | $1.23B |
China | $779M |
France | $722M |
Canada | $619M |
Netherlands | $342M |
Spain | $308M |
South Korea | $64.1M |
Total funding amount raised by stage in the Gene Therapy sector
Over the last 10 years, the Gene Therapy sector have seen $486M into Seed Stage funding rounds, $11.2B into Early Stage funding rounds and $4.99B go into Late Stage funding rounds.
Funding Stage | Total Funding |
|---|---|
Early Stage | $11.2B |
Post IPO | $5.96B |
Late Stage | $4.99B |
Grant | $1.94B |
Seed Stage | $486M |
PE | $276M |
Debt | $270M |
Recent Funding Rounds in Gene Therapy
In the year 2026, till February 2026, Gene Therapy companies have raised $91.7M in equity funding across 3 rounds.
In the same period last year (i.e. till February 2025), Gene Therapy companies had raised $318M across 9 rounds.
So, 2026 has seen a 71.15% drop in funding in Gene Therapy companies as compared to 2025.
Here are some recent, important funding rounds in Gene Therapy:
Company | Round Raised | Amount Raised | Funding Date | Investors |
|---|---|---|---|---|
Seed | 8034 | Feb 20, 2026 | ||
Series B | 1349 | Feb 06, 2026 | - | |
Series C | 8094 | Jan 08, 2026 | ||
Series A | 6794 | Dec 11, 2025 | ||
Series C | 2703 | Dec 11, 2025 | - |
Top Investors in Gene Therapy
HHS is the top investor in Gene Therapy companies based on number of companies invested.
Here are some top investors in Gene Therapy:
Investor | Location | Top Portfolio Companies |
|---|---|---|
Washington, DC (United States) | ||
Boston (United States) | ||
New York City (United States) | ||
Menlo Park (United States) | ||
M&A activity in Gene Therapy
In the year 2025, till December 2025, 10 acquisitions happened in Gene Therapy sector. Last year, in 2024, a total of 7 acquisitions happened in Gene Therapy sector.
Here are some recent, important acquisitions in Gene Therapy:
Company | Acquisition Type | Acquisition Date | Acquirers |
|---|---|---|---|
Business Acquisition | Dec 15, 2025 | ||
Business Acquisition | Oct 27, 2025 | ||
Business Acquisition | Oct 24, 2025 | ||
Business Acquisition | Sep 18, 2025 | ||
Business Acquisition | Jun 17, 2025 |
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Acquisition trends in Gene Therapy
Here are the acquisition trends in Gene Therapy:
- Total Number of Acquisitions
Year | No. of companies |
|---|---|
2026 | - |
2025 | 10 |
2024 | 7 |
2023 | 7 |
2022 | 7 |
2021 | 8 |
2020 | 5 |
2019 | 7 |
2018 | 4 |
2017 | 2 |
IPOs in Gene Therapy
In the year 2026, till January 2026, 1 IPO happened in Gene Therapy sector.
Here are some recent, important IPOs in Gene Therapy:
Company | IPO Date | Exchange Symbol |
|---|---|---|
Jan 09, 2026 | Hong Kong Exchanges (HKG) | |
Mar 10, 2025 | Taipei Stock Exchange (TT) | |
Oct 24, 2024 | National Association of Securities Dealers Automated Quotations (NASDAQ) | |
Dec 19, 2023 | National Association of Securities Dealers Automated Quotations (NASDAQ) | |
Dec 30, 2021 | Hong Kong Exchanges (HKG) |
Colleges which produce the most Gene Therapy companies
Companies founded by alumni from top colleges in the Gene Therapy sector
Most number of Gene Therapy startups have been founded by alumni from Harvard University, Massachusetts Institute of Technology and University of California (Berkeley).
College | No. of companies |
|---|---|
Harvard University | 25 |
Massachusetts Institute of Technology | 24 |
University of California (Berkeley) | 14 |
Stanford University | 12 |
Harvard Business School | 11 |
University of Oxford | 8 |
Yale University | 8 |
Columbia University | 7 |
Cornell University | 7 |
Duke University | 6 |
Total funding in companies founded by alumni from top colleges in the the Gene Therapy sector
In the last 10 years, Massachusetts Institute of Technology graduates' Gene Therapy companies have raised the most funding among top colleges. University of Toronto alumni are second, and Cornell University alumni are third.
College | Total Funding |
|---|---|
Massachusetts Institute of Technology | $7.41B |
University of Toronto | $4.52B |
Cornell University | $4.35B |
Harvard University | $3.35B |
Duke University | $1.36B |
University of California (Berkeley) | $1.2B |
Stanford University | $895M |
Columbia University | $643M |
Harvard Business School | $598M |
Princeton University | $543M |
Top News in Gene Therapy
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AskBio Completes Enrollment in Phase 2 Trial of AB-1002 Gene Therapy for Heart FailureGlobeNewswire•Apr 01, 2026•AskBio, Bayer
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MeiraGTx Announces FDA Breakthrough Therapy Designation for AAV2-hAQP1GlobeNewswire•Mar 26, 2026•MeiraGTx
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Abeona Therapeutics Reports Full Year 2025 Financial ResultsGlobeNewswire•Mar 17, 2026•Abeona Therapeutics
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Opus Genetics Announces Financial Results for Full Year 2025GlobeNewswire•Mar 10, 2026•Opus Genetics
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REGENXBIO’s Hunter Rejection Hinged on Inadequate Controls, Surrogate EndpointBioSpace•Mar 03, 2026•Regenxbio
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