About Ascension Ventures
Ascension Ventures is a venture capital firm founded in 2001. It is primarily based out of St. Louis, United States. As of Jun 2026, Ascension Ventures is an active investor, having invested in 105 companies, with 2 new investments in the last 12 months. It primarily invests in Series B round in United States based startups. Its investments are spread across a wide range of sectors from Life Sciences to HealthTech and Enterprise Applications. Most recently it participated in the $***** Series B round of Rejoni Overall, Ascension Ventures portfolio has seen 1 unicorn, 8 IPOs and 46 acquisitions including key companies like Stream, Omnicell and Phreesia. A lot of funds co-invest with Ascension Ventures, with names like Kaiser Permanente Ventures sharing a substantial percentage of its portfolio. Ascension Ventures has team of 6 people including 2 partners.Key Metrics
Team Members
Portfolio Sectors
Portfolio Locations
Rounds of Entry
Series A, Seed & 8 more
Portfolio IPOs
Portfolio Acquisitions
Portfolio Unicorns
Portfolio Soonicorns
Ascension Ventures' List of Top Investments
Ascension Ventures has a portfolio of 105 companies, one of which is a Unicorn. Their most notable investments are in Renovia and NeuroStar.Their portfolio spans across United States, United Kingdom and Austria. They have invested in Life Sciences, HealthTech, Enterprise Applications and 13 other sectors, across stages such as Series A, Seed and 8 more. Here is the list of top investments by Ascension Ventures:1. Stream
Workplace financial wellbeing platform that provides employees with tools to access earned wages. It offers a suite of tools that help users earn, access, save, spend, and plan their money in one unified mobile application. It includes features such as on-demand access to earned wages, budgeting and spending insights, savings products, financial coaching, and access to loans and pension consolidation tools. It also provides discounts and rewards to help reduce the cost of living and improve day-to-day financial resilience.
Key facts about Stream
- Founded Year: 2018
- Location: London (United Kingdom)
- Stage: Acquired
- Total Funding till date: $228M
- Employee Count: 321 as on Jun 30, 2026
- Investors: BlackRock, QED Investors and 53 Others
- Latest Funding Round: Series D, Jan 20, 2026, $*****
- Highlight: Acquired
2. Omnicell
Developer of automated dispensing system for pharmacies. It provides hardware/software systems for medication dispensing include solutions from the point of entry into the hospital through the central pharmacy, nursing unit, operating room, and patient bedside. The supply management systems promote cost control and charge capture for payer reimbursement, and improve management and reordering of inventory. Products range from high-security, closed-cabinet systems, and software to open-shelf and combination systems in the nursing unit, cath lab, and operating room.
Key facts about Omnicell
- Founded Year: 1992
- Location: Mountain View (United States)
- Annual Revenue: $1B+ as on Dec 31, 2025
- Stage: Public
- Total Funding till date: $20M
- Employee Count: 3,394 as on Jun 30, 2026
- Investors: Ascension Ventures, ABS Capital and 7 Others
- Latest Funding Round: Post IPO, May 22, 2017, $*****
- Highlight: Public
3. Zen Educate
Provider of platform connecting educators with schools for temporary staffing. The platform enables schools to directly book educators based on their specific needs and preferences. It offers a streamlined process for finding and securing temporary teaching staff. The platform also provides educators with access to various job opportunities.
Key facts about Zen Educate
- Founded Year: 2017
- Location: London (United Kingdom)
- Annual Revenue: £50M - £100M as on Dec 31, 2024
- Valuation: $*****
- Stage: Series B
- Total Funding till date: $76.3M
- Employee Count: 2,198 as on Jun 30, 2026
- Investors: Round2 Capital Partners, Ascension Ventures and 64 Others
- Latest Funding Round: Series B, May 21, 2024, $*****
- Highlight: Editors' Pick
4. Phreesia
Provider of a patient check-in and registration platform for healthcare organizations. The platform replaces the outdated patient clipboard with a free wireless touch screen and swipe card enabled PhreesiaPad. The patient self-service solution includes electronic payment applications, clinical and administrative data collection, and consent form management, online appointment & referral management, revenue cycle management, registration, clinical screening tools, patient engagement.
Key facts about Phreesia
- Founded Year: 2005
- Location: New York City (United States)
- Annual Revenue: $100M - $500M as on Jan 31, 2026
- Stage: Public
- Total Funding till date: $109M
- Employee Count: 1,495 as on Jun 30, 2026
- Investors: MFS Investment Management, Ardan Equity Partners and 17 Others
- Latest Funding Round: Post IPO, Nov 13, 2019, $*****
- Highlight: Public
5. RefleXion
Provider of biology-guided radiotherapy system. Its patented technology leverages Positron Emission Tomography (PET) which allows tumors to continuously signal their location during treatment and guides personalized radiation therapy. The technology has applications in the treatment of Lung, prostate, and Breast cancers.
Key facts about RefleXion
- Founded Year: 2009
- Location: Hayward (United States)
- Stage: Series F
- Total Funding till date: $542M
- Employee Count: 154 as on Jun 30, 2026
- Investors: T. Rowe Price, GT Healthcare Capital Partners and 24 Others
- Latest Funding Round: Series F, Nov 13, 2023, $*****
- Highlight: Editors' Pick
Ascension Ventures' Year-on-Year Investment Trends
Ascension Ventures has invested in 106 companies over the last 22 years, with an average of 3 new investments annually in the last 10 years. In 2025, it made 2 investments, while as of Jun 2026, it has made 2 investments in this year. Its most recent first time investment was in Stream and most recent follow-on round was in Rejoni.Year | No. of Investments | ||
|---|---|---|---|
1st Round | Follow-on | Total | |
2026 (YTD) | 1 | 1 | 2 |
2025 | 1 | 1 | 2 |
2024 | 2 | 1 | 3 |
2023 | 6 | 2 | 8 |
2022 | 1 | 0 | 1 |
2021 | 2 | 1 | 3 |
2020 | 4 | 2 | 6 |
2019 | 2 | 1 | 3 |
2018 | 5 | 2 | 7 |
2017 | 10 | 0 | 10 |
Ascension Ventures' Investments by Stage
Ascension Ventures has made 15 investments in Series A stage with an average round size of $18.3M, 14 investments in Seed stage with an average round size of $2.61M and 13 investments in Series B stage with an average round size of $22M.Stage of entry | No. of Investments |
|---|---|
Series A | 15 |
Seed | 14 |
Series B | 13 |
Series D | 13 |
Series C | 6 |
Others | 11 |
Note: We have considered here, only first round of investments
Ascension Ventures' Investments by Sector
Ascension Ventures has a diverse portfolio, with companies operating in the HealthTech, Enterprise Applications, Life Sciences, High Tech and Vertical SaaS. Notably, it has invested in 84 Tech companies, 79 Enterprise (B2B) companies, 41 Software companies and at least 23 companies focusing on Tech hardware.Sector | No. of Investments |
|---|---|
HealthTech | 36 |
Enterprise Applications | 31 |
Life Sciences | 31 |
High Tech | 13 |
Vertical SaaS | 13 |
Others | 45 |
Note: We have considered here, only first round of investments
Ascension Ventures' Investments by Geography
Ascension Ventures has made most investments in United States (59), followed by United Kingdom where it has made 13 investments.Country | No. of Investments |
|---|---|
United States | 59 |
United Kingdom | 13 |
Note: We have considered here, only first round of investments
Ascension Ventures' recent investments
Ascension Ventures has made 2 investments in 2026 so far - Rejoni and Stream.Here are the most recent investments by Ascension Ventures:
Filter this listDate | Company | Location | Round Details | Round Amount | Co-Investors |
|---|---|---|---|---|---|
Jun 16, 2026 | United States | Series B | 8302 | [+6] | |
Jan 20, 2026 | United Kingdom | Series D | 3250 | [+6] | |
Dec 15, 2025 | United States | Series A | 6076 | ||
Nov 11, 2025 | United States | Series A | 7557 | [+4] | |
Dec 09, 2024 | United States | Series D | 1511 | [+11] |
Unicorns in Ascension Ventures' Portfolio
Ascension Ventures has 1 unicorn in its portfolio - Olive. The most recent unicorn in their portfolio is Olive which became a unicorn in 2020, 2 years after Ascension Ventures first invested in it.Here is a list of unicorns in Ascension Ventures' portfolio:
Tracxn Score | Company | Short Description | Founded year | Sector | Location | Company Stage | First Investment/ Acquisition Details |
|---|---|---|---|---|---|---|---|
58 | Provider of AI-based platform for administrative solutions | 2012 | Columbus | Series H | tcnurlg |
IPOs and Publicly Listed companies in Ascension Ventures' Portfolio
8 of Ascension Ventures' portfolio companies have become public. EBR Systems got listed on the Australian Securities Exchange (ASX), in Nov 2021 at marketcap of $18.1M and Alignment Health got listed on the National Association of Securities Dealers Automated Quotations (NASDAQ).Here are Ascension Ventures' portfolio companies that went public:
Company | IPO Date | First Invested on | First Round of Investment | Round Size |
|---|---|---|---|---|
Nov 24, 2021 | Nov 14, 2017 | Series F | 3031 | |
Mar 26, 2021 | - | - | 1773 | |
Jul 19, 2019 | Apr 23, 2010 | Series D | 3002 | |
Jun 28, 2018 | Jun 13, 2017 | Series G | 6773 | |
Jul 25, 2014 | Feb 03, 2011 | Series D | 9793 |
Acquired companies in Ascension Ventures' Portfolio
46 companies from Ascension Ventures' portfolio have been acquired. The most recent acquisition was Syapse in Jan 2025 by N-Power Medicine for $*****.Here are Ascension Ventures' portfolio companies that got acquired most recently:
Company | Acquisition Date | First Invested on | First Round of Investment | Round Size |
|---|---|---|---|---|
Jan 13, 2025 | Jan 12, 2016 | Series C | 2618 | |
Jan 02, 2025 | Jun 16, 2008 | PE | 7650 | |
Jul 09, 2024 | Jun 05, 2013 | Series D | 6687 | |
Jun 11, 2024 | Sep 08, 2020 | Seed | 2856 | |
Jan 31, 2024 | Sep 15, 2017 | Seed | 2946 |
Team profile of Ascension Ventures
Ascension Ventures has a team of 6 members including 2 Partners and 1 Principal located in United States. Ascension Ventures' team sits on the board of 2 companies.Here is a list of all team members in Ascension Ventures:
Name | Designation | Location | Board Memberships | Contact Details |
|---|---|---|---|---|
Partner | St. Louis | |||
Partner | St. Louis | - | - | |
Principal | Houston | - | - |
Co-investors of Ascension Ventures
Over the past 22 years, 451 investors have co-invested in Ascension Ventures's portfolio companies. This includes funds and angels.
- Invested before Ascension Ventures: Incept, HLM Venture Partners and 173 others have invested in rounds before Ascension Ventures. There are 4 companies where Incept has invested before Ascension Ventures and 3 companies where HLM Venture Partners has invested before Ascension Ventures.
- Top Co-investors of Ascension Ventures: 159 investors entered a company along with Ascension Ventures. These include investors like Kaiser Permanente Ventures (4 companies).
- Invested after Ascension Ventures: A total of 117 investors have invested in Ascension Ventures's portfolio after their investments. Top Investors include Ascension (6 companies), Mitsui (2 companies) and Cobalt Ventures (2 companies).
Recent News related to Ascension Ventures
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Rejoni, Inc. Secures $25 Million in Financing for Juveena® Hydrogel SystemThe Joplin Globe•Jun 16, 2026•Rejoni, Iyengar Capital Partners, Clavystbio, AMED Ventures and 5 others
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Voxmind Raises £546K Pre-Seed Funding Led By Ascension VenturesStartup Rise EU•May 26, 2026•VoxMind AI, Ascension Ventures, Ascension
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TUAL Secures £1.5m For Commercial EV Charging InfrastructureManufacturing Management•Jan 21, 2026•Tual, PT1, Ascension Ventures
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British workplace finance platform Stream secures €76M funding, bringing total to €194MEU-Startups•Jan 20, 2026•Stream, Sofina, Better Society Capital, Smash Capital and 4 others
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Farmdrive secures £1m pre-seed funding for European expansion.Silicon Republic•Nov 14, 2025•Farmdrive, Techstart Ventures, Angel Invest Ventures, Ascension Ventures
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NextSense Raises $16 Million Series A to Launch the World’s First Truly-Wireless Earbuds with EEG SensorsThe Joplin Globe•Nov 11, 2025•Corundum Neuroscience, Satori Capital, Ascension Ventures, NextSense and 1 other
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Cala® Health Closes Oversubscribed $50 Million Financing To Propel Growthintelligence360•Dec 23, 2024•Cala Health, Vertex Growth, Nexus NeuroTech Ventures, Johnson & Johnson and 9 others
