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About BioAdvance

BioAdvance is a venture capital firm founded in 2002. It is primarily based out of Radnor, United States. As of May 2026, BioAdvance is an active investor, having invested in 78 companies, with 1 new investment in the last 12 months. It primarily invests in Seed round in United States based startups. Its investments are spread across a wide range of sectors from Life Sciences to HealthTech and High Tech. Most recently it participated in the $***** Series A round of Latus Overall, BioAdvance portfolio has seen 3 IPOs and 15 acquisitions including key companies like WellSheet, Keriton and Immunome. A lot of funds co-invest with BioAdvance, with names like Novartis Venture Fund sharing a substantial percentage of its portfolio. BioAdvance has team of 8 people including 3 partners.
Key Metrics
Portfolio Sectors
Portfolio Locations
Rounds of Entry
Seed, Series A & 1 more
Portfolio IPOs
Portfolio Acquisitions
Portfolio Soonicorns
Deals in last 12 months

BioAdvance's List of Top Investments

BioAdvance has a portfolio of 78 companies. Their most notable investments are in Keriton and VESTECK.Their portfolio spans across United States and United Kingdom. They have invested in Life Sciences, HealthTech, High Tech and 3 other sectors, across stages such as Seed, Series A  and 1 more. Here is the list of top investments by BioAdvance:
Developer of therapeutics to treat rare diseases. Their lead program RAPATANE is a novel proprietary formulation of sirolimus for topical application for Pachyonychia Congenita- an autosomal dominant skin disorder that affects skin and nails. This disease has got an Orphan designation by the FDA & EMEA and the company has received an FDA Orphan Drug grant for development of their sirolimus-based treatment for the same.

Key facts about Palvella Therapeutics

Provider of a web application for care quality and productivity improvement. The caregivers can view the patient’s timeline of visits and information updates, pertinent lab values, list of medications, risks that may affect care, and the team working with the patient. The platform also provides data visualizations to conduct a more detailed analysis.

Key facts about WellSheet

  • Founded Year: 2015
  • Location: New York City (United States)
  • Stage: Acquired
  • Total Funding till date: $9.94M
  • Employee Count: 14 as on Jun 30, 2026
  • Investors: REDO Ventures, BioAdvance and 8 Others
  • Latest Funding Round: Series A, Sep 06, 2022, $*****
  • Highlight: Acquired
Feeding management platform ensuring safe, efficient care for hospitalized infants and children. This innovative platform, designed by clinicians, streamlines workflows, enhances efficiency, and drives data-driven safety in neonatal and pediatric hospital settings. It optimizes breast milk management, boosts lactation support, and promotes parent engagement. The platform offers multilayered validations for safe feeds, simplifies recipe preparation, and provides real-time analytics with quality metrics. It connects families with care teams, offering updates and secure messaging. The solution is HIPAA-compliant, offers secure EMR integration, and is SOC 2 Type 2 certified. It supports clinical dietitians, lactation consultants, bedside nurses, and parents, ensuring accuracy, reliability, and improved communication. This comprehensive, cloud-based SaaS solution is built with clinicians and evolves with your needs, offering robust training and technical support.

Key facts about Keriton

  • Founded Year: 2016
  • Location: Philadelphia (United States)
  • Stage: Acquired
  • Total Funding till date: $2.11M
  • Employee Count: 25 as on Jun 30, 2026
  • Investors: Penn Medicine, BioAdvance and 7 Others
  • Latest Funding Round: Seed, Sep 21, 2018, $*****
  • Highlight: Acquired
Developer of antibody-based therapeutics for treating cancer. Its lead oncology discovery program targets IL-38, a lesser-known member of the IL-1 family of cytokines. It allows tumors to evade the immune system response efforts. It utilizes B-cells from early-stage cancer patients and by using its fusion cell technology, RealMab, converts these B-cells into stable hybridomas that express thousands of affinity-matured monoclonal antibodies (mAbs) enriched for functional tumor antigen binding.

Key facts about Immunome

  • Founded Year: 2008
  • Location: Philadelphia (United States)
  • Annual Revenue: $1M - $10M as on Dec 31, 2025
  • Stage: Public
  • Total Funding till date: $54.2M
  • Employee Count: 256 as on Jun 30, 2026
  • Investors: Evolution VC Partners, BioAdvance and 4 Others
  • Latest Funding Round: Post IPO, Apr 26, 2021, $*****
  • Highlight: Public
3D bioprinting solutions: bioprinters, bioinks, and software for tissue engineering. They provide simplified bioprinting with versatile desktop 3D bioprinters, diverse bioinks, and user-friendly software. Their technology empowers researchers to design and engineer 3D tissues for applications like regenerative medicine, drug discovery, and disease modeling. They offer tools for extrusion bioprinting, precision printing, and creating complex geometries. Their products include bioprinters, bioinks for various tissues (liver, heart, bone, etc.), and essential reagents. They support the scientific community with resources like bioprinting protocols, blogs, webinars, and application notes. They also have an online shop with products like nozzles, alginate, photoinitiators, and calcium chloride. They offer login access for software, services, and support. They are focused on advancing bioprinting and regenerative medicine.

Key facts about Allevi

BioAdvance's Investments by Stage

BioAdvance has made 32 investments in Seed stage with an average round size of $1.44M, 12 investments in Series A stage with an average round size of $20.4M and 6 investments in Series B stage with an average round size of $14.7M.
Here are BioAdvance's investments by stage:
Stage of entry
No. of Investments
Seed
32
Series A
12
Series B
6
Breakdown of BioAdvance's investments by stage of entrySeed (32)Series A (12)
Note: We have considered here, only first round of investments

BioAdvance's Investments by Sector

BioAdvance has a diverse portfolio, with companies operating in the Life Sciences, HealthTech, Enterprise Applications, Sustainability Tech and High Tech. Notably, it has invested in 67 Tech companies, 60 Enterprise (B2B) companies, 26 Software companies and at least 12 companies focusing on Tech hardware.
Here are BioAdvance's investments by sector:
Sector
No. of Investments
Life Sciences
36
HealthTech
14
Enterprise Applications
11
Sustainability Tech
7
High Tech
5
Others
7
Breakdown of BioAdvance's investments by sectorsLife Sciences (36)HealthTech (14)
Note: We have considered here, only first round of investments

BioAdvance's Investments by Geography

BioAdvance has made most investments in United States (50), followed by United Kingdom where it has made 1 investment.
Here are BioAdvance's investments by geography:
Country
No. of Investments
United States
50
United Kingdom
1
Breakdown of BioAdvance's investments by countriesUnited States (50)United Kingdom (1)
Note: We have considered here, only first round of investments

BioAdvance's recent investments

BioAdvance has made 1 investments in 2026 so far - Latus.
Here are the most recent investments by BioAdvance:
Date
Company
Location
Round Details
Round Amount
Co-Investors
May 04, 2026
United States
Series A
8730
  [+6]
Oct 29, 2024
United States
Seed
1395
Jul 19, 2023
United States
Grant (prize money)
8241
  [+3]
Dec 30, 2022
United States
Series D
2426
  [+5]
Dec 12, 2022
United States
Seed
2646

IPOs and Publicly Listed companies in BioAdvance's Portfolio

3 of BioAdvance's portfolio companies have become public. Immunome got listed on the National Association of Securities Dealers Automated Quotations (NASDAQ), in Oct 2020 at marketcap of $120M and Annovis got listed on the New York Stock Exchange (NYSE) at marketcap of $39.1M.
Here are BioAdvance's portfolio companies that went public:
Company
IPO Date
First Invested on
First Round of Investment
Round Size
Oct 02, 2020
May 24, 2010
Seed
9569
Jan 29, 2020
Jun 02, 2010
Seed
7022
May 20, 2014
Oct 01, 2013
Series A
5672

Acquired companies in BioAdvance's Portfolio

15 companies from BioAdvance's portfolio have been acquired. The most recent acquisition was WellSheet in Jun 2026 by Elsevier for $*****.
Here are BioAdvance's portfolio companies that got acquired most recently:
Company
Acquisition Date
First Invested on
First Round of Investment
Round Size
Jun 08, 2026
Oct 27, 2017
Seed
1721
Jan 28, 2026
Feb 16, 2017
Seed
5779
May 21, 2025
Dec 20, 2018
Series B
3832
Sep 20, 2022
Aug 14, 2019
Series A
5105
May 06, 2021
-
-
7252

Team profile of BioAdvance

BioAdvance has a team of 8 members including 3 Partners, 2 Venture Partners and 2 Principals located in United States. BioAdvance's team sits on the board of 1 company.
Here is a list of all team members in BioAdvance:
Name
Designation
Location
Board Memberships
Contact Details
Partner
Vero Beach
-
Partner
Princeton
Partner
Wayne
-
Venture Partner
United States
-
-
Venture Partner
United States
-
-
Principal
-
-
Principal
-
-

Co-investors of BioAdvance

Over the past 22 years, 162 investors have co-invested in BioAdvance's portfolio companies. This includes funds and angels.

  • Invested before BioAdvanceHHS, Ben Franklin Technology Partners and 25 others have invested in rounds before BioAdvance. There are 5 companies where HHS has invested before BioAdvance and 4 companies where Ben Franklin Technology Partners has invested before BioAdvance.
  • Top Co-investors of BioAdvance56 investors entered a company along with BioAdvance. These include investors like Novartis Venture Fund (3 companies).
  • Invested after BioAdvanceA total of 79 investors have invested in BioAdvance's portfolio after their investments. Top Investors include HHS (11 companies), Robin Hood Ventures (2 companies) and NIH (2 companies).

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