About BlueIO
BlueIO is a venture capital firm founded in 2012. It is primarily based out of Boston, United States. As of Mar 2024, BlueIO has invested in 16 companies. It primarily invests in Series A round in United States based startups. Its investments are spread across a wide range of sectors from HealthTech to Life Sciences and Enterprise Applications. Most recently it participated in the $***** Series A round of CyberSaint Security Overall, BlueIO portfolio has seen 2 IPOs and 2 acquisitions including key companies like Sanara MedTech, GreenLight Biosciences and Causemo. A lot of funds co-invest with BlueIO, with names like LaunchCapital sharing a substantial percentage of its portfolio.Key Metrics
Portfolio Count
Portfolio Sectors
Portfolio Locations
Rounds of Entry
Series A, Seed & 3 more
Portfolio IPOs
Portfolio Acquisitions
Portfolio Soonicorns
BlueIO's List of Top Investments
BlueIO has a portfolio of 16 companies. Their most notable investments are in CyberSaint Security and Lumicell Diagnostics.Their portfolio spans across United States and Canada. They have invested in HealthTech, Life Sciences, Enterprise Applications and 11 other sectors, across stages such as Series A, Seed and 3 more. Here is the list of top investments by BlueIO:1. Cellworks
Developer of a biosimulation platform. It has developed a biosimulation platform that uses computational modeling and offers the life science industry a framework for designing therapeutics to transform entirely empirical drug development. The platform is used for predicting responses to FDA-approved cancer therapies, & provides personalized cancer therapy recommendations.
Key facts about Cellworks
- Founded Year: 2005
- Location: San Jose (United States)
- Annual Revenue: ₹10 - ₹50 Cr as on Mar 31, 2025
- Stage: Series B
- Total Funding till date: $16.5M
- Employee Count: 157 as on Aug 31, 2026
- Investors: Bering Capital, Artiman and 3 Others
- Latest Funding Round: Series B, Dec 26, 2012, $*****
- Highlight: Editors' Pick
Developer of fluorescence-guided imaging technologies to help surgeons detect residual cancer tissue during operations. The company’s product is the Lumicell Direct Visualization System, designed to provide real-time illumination of cancerous tissue within the breast cavity during the initial lumpectomy, potentially reducing repeat surgeries. Lumicell’s proprietary, pan-oncologic optical imaging agent is also being explored across a wide variety of solid tumor indications.
Key facts about Lumicell Diagnostics
- Founded Year: 2008
- Location: Wellesley (United States)
- Valuation: $*****
- Stage: Series D
- Total Funding till date: $361M
- Employee Count: 62 as on Aug 31, 2026
- Investors: Kodiak Venture Partners, Rivas Capital and 8 Others
- Latest Funding Round: Series D, Apr 22, 2025, $*****
- Highlight: Editors' Pick
_1574231750365.png?format=webp&height=120&width=120){kind=logo}
Developer of therapeutics for infectious disease. The platform has developed wound care products that include BIAKŌS for antimicrobial skin and wound cleaning and PULSAR II is the wound irrigation system. The platform also developed surgical products that include CellerateRX is surgical powder.
Key facts about Sanara MedTech
- Founded Year: 1982
- Location: Fort Worth (United States)
- Annual Revenue: $100M - $500M as on Dec 31, 2025
- Stage: Public
- Employee Count: 113 as on Aug 31, 2026
- Investors: BlueIO and The Catalyst Group
- Latest Funding Round: PE, $*****
- Highlight: Public
Developer of a platform for RNA-based products for the life science industry. It offer platform that is used for vaccine development, antibody therapies, pandemic preparation, crop management, plant protection, support the health of bees and other pollinators
Key facts about GreenLight Biosciences
- Founded Year: 2008
- Location: Lexington (United States)
- Annual Revenue: $1M - $10M as on Dec 31, 2022
- Stage: Public
- Total Funding till date: $225M
- Employee Count: 175 as on Aug 31, 2026
- Investors: Trinity Capital, Kodiak Venture Partners and 36 Others
- Latest Funding Round: Post IPO, Apr 07, 2025, $*****
- Highlight: Public
Developer of platforms for automated cyber risk management and analysis. Software facilitates the identification and assessment of security vulnerabilities across organizational infrastructure. Tools monitor compliance requirements and track risk mitigation progress in real time. Platforms provide data visualization for internal audits and technical security reporting.
Key facts about CyberSaint Security
- Founded Year: 2016
- Location: Boston (United States)
- Stage: Series A
- Total Funding till date: $24.7M
- Employee Count: 29 as on Sep 30, 2026
- Investors: Jere Doyle Enterprises, BlueIO and 6 Others
- Latest Funding Round: Series A, Mar 15, 2024, $*****
BlueIO's Year-on-Year Investment Trends
Its most recent first time investment was in Wallit and most recent follow-on round was in CyberSaint Security.Year | No. of Investments | ||
|---|---|---|---|
1st Round | Follow-on | Total | |
2026 (YTD) | 0 | 0 | 0 |
2025 | 0 | 0 | 0 |
2024 | 0 | 1 | 1 |
2023 | 0 | 0 | 0 |
2022 | 0 | 0 | 0 |
2021 | 0 | 1 | 1 |
2020 | 0 | 0 | 0 |
2019 | 2 | 0 | 2 |
2018 | 3 | 0 | 3 |
2017 | 1 | 0 | 1 |
BlueIO's Investments by Stage
BlueIO has made 2 investments in Series A stage with an average round size of $3.21M, 1 investment in Seed stage with an average round size of $2.6M, 1 investment in Series B stage with an average round size of $24M, 1 investment in Series C stage with an average round size of $28.7M and 1 investment in Series D stage with an average round size of $50M.Stage of entry | No. of Investments |
|---|---|
Series A | 2 |
Seed | 1 |
Series B | 1 |
Series C | 1 |
Series D | 1 |
Note: We have considered here, only first round of investments
BlueIO's Investments by Sector
BlueIO has a diverse portfolio, with companies operating in the Enterprise Applications, Enterprise Infrastructure, FinTech, Life Sciences and High Tech. Notably, it has invested in 13 Tech companies, 9 Enterprise (B2B) companies, 7 Software companies and at least 5 companies focusing on Consumer (B2C).Sector | No. of Investments |
|---|---|
Enterprise Applications | 3 |
Enterprise Infrastructure | 2 |
FinTech | 2 |
Life Sciences | 2 |
High Tech | 1 |
Others | 1 |
Note: We have considered here, only first round of investments
BlueIO's Investments by Geography
BlueIO has made most investments in United States (6).BlueIO's recent investments
BlueIO has not made any investment in 2026 so far.Here are the most recent investments by BlueIO:
Filter this listDate | Company | Location | Round Details | Round Amount | Co-Investors |
|---|---|---|---|---|---|
Mar 15, 2024 | United States | Series A | 1780 | [+2] | |
Jul 14, 2021 | United States | Series C | 1131 | [+8] | |
Sep 16, 2019 | United States | Seed | 2218 | [+2] | |
Jan 08, 2019 | United States | Series D | 3839 | [+5] | |
May 29, 2018 | United States | Series A | 4245 |
IPOs and Publicly Listed companies in BlueIO's Portfolio
2 of BlueIO's portfolio companies have become public. GreenLight Biosciences got listed on the National Association of Securities Dealers Automated Quotations (NASDAQ), in Feb 2022 at marketcap of $44.9M and Sanara MedTech got listed on the National Association of Securities Dealers Automated Quotations (NASDAQ).Here are BlueIO's portfolio companies that went public:
Company | IPO Date | First Invested on | First Round of Investment | Round Size |
|---|---|---|---|---|
Feb 03, 2022 | Jan 08, 2019 | Series D | 2729 | |
May 15, 2018 | - | - | 4229 |
_1574231750365.png?devicePixelRatio=2&height=20&width=20){kind=logo}
Acquired companies in BlueIO's Portfolio
2 companies from BlueIO's portfolio have been acquired. The most recent acquisition was NeighborSchools in Dec 2022 by Higher Ground Education for $*****.Here are BlueIO's portfolio companies that got acquired most recently:
Company | Acquisition Date | First Invested on | First Round of Investment | Round Size |
|---|---|---|---|---|
Dec 01, 2022 | - | - | 8038 | |
Aug 14, 2019 | - | - | 3321 |
_1572353873359.png?devicePixelRatio=2&height=20&width=20){kind=logo}
Co-investors of BlueIO
Over the past 9 years, 50 investors have co-invested in BlueIO's portfolio companies. This includes funds and angels.
- Invested before BlueIO: HHS, National Science Foundation and 14 others have invested in rounds before BlueIO. There is 1 company where HHS has invested before BlueIO and 1 company where National Science Foundation has invested before BlueIO.
- Top Co-investors of BlueIO: 12 investors entered a company along with BlueIO. These include investors like LaunchCapital (1 company).
- Invested after BlueIO: A total of 22 investors have invested in BlueIO's portfolio after their investments. Top Investors include Serum Life Sciences (1 company), Flu Lab (1 company) and Morningside (1 company).
Recent News related to BlueIO
•
CyberSaint Announces $21M Series A to Accelerate Global ExpansionBusiness Wire•Mar 20, 2024•CyberSaint Security, Riverside Acceleration Capital, BlueIO, Audeo Capital and 1 other
•
Virsec hits $137 million investment milestone after latest roundSecurityBrief•Jul 22, 2021•Virsec Systems, BlueIO, Allen & Company, Intuitive Venture Partners and 5 others
•
Virsec Secures $100 Million “Show of Force” Investment as it Redefines How Software is SecuredGlobeNewswire•Jul 14, 2021•Virsec Systems, BlueIO, Allen & Company, Arena Holdings and 7 others
•
Wallit Raises $2.6M in FundingFinSMEs•Sep 16, 2019•Wallit, BlueIO, Mendoza Ventures, BoxOne Ventures
•
GreenLight Biosciences Announces $50 Million Funding RoundPR Newswire•Jan 08, 2019•GreenLight Biosciences, S2G Ventures, Baird Capital, Continental Grain Company and 4 others
•
CyberSaint Security Raises $3 Million In Growth FinancingPR Newswire•May 29, 2018•cybersaint.com, CyberSaint Security, Audeo Capital, BlueIO
•
Virsec Closes $24 Million In Series B FundingReuters•Mar 20, 2018•Virsec Systems, BlueIO, Artiman, Amity Ventures and 2 others
•
Lumicell Raises $28.7M Series C Citybizlist•Dec 07, 2017•Lumicell Diagnostics, LaunchCapital, BlueIO
