About Cantos Ventures
Cantos Ventures is a venture capital firm founded in 2016. It is primarily based out of San Francisco, United States. As of Oct 2025, Cantos Ventures is an active investor, having invested in 71 companies, with 2 new investments in the last 12 months. It primarily invests in Seed round in United States based startups. Its investments are spread across a wide range of sectors from High Tech to Enterprise Applications and Environment Tech. Most recently it participated in the $***** Seed round of Adaptyx Biosciences Overall, Cantos Ventures portfolio has seen 6 unicorns and 9 acquisitions including key companies like Public, Castelion and SkyRyse. A lot of funds co-invest with Cantos Ventures, with names like Refactor Capital sharing a substantial percentage of its portfolio. Cantos Ventures has team of 8 people including 5 partners.Key Metrics
Team Members
Portfolio Sectors
Portfolio Locations
Rounds of Entry
Seed & Series A
Portfolio Acquisitions
Portfolio Unicorns
Deals in last 12 months
Cantos Ventures' List of Top Investments
Cantos Ventures has a portfolio of 71 companies, including 6 unicorns. Their most notable investments are in Sixfold Bioscience and Dusty Robotics.Their portfolio spans across United States, United Kingdom and Canada. They have invested in High Tech, Enterprise Applications, Environment Tech and 23 other sectors, across stages such as Seed, Series A stages. Here is the list of top investments by Cantos Ventures:1. Public
Multi-asset investment platform for individuals. It enables investing in stocks, treasuries, bonds, crypto, ETFs, and alternative assets. It allows users to buy and sell shares based on real-time prices. Features tools for accessing historical analysis, tracking investments, referencing news articles for investing, investment thesis, public talks, live news, and more. Application is made available on Android and iOS platforms.
Key facts about Public
- Founded Year: 2019
- Location: New York City (United States)
- Valuation: $*****
- Stage: Series D
- Total Funding till date: $421M
- Employee Count: 880 as on Jul 31, 2026
- Investors: Accel, Atlant Ventures and 58 Others
- Latest Funding Round: Series D, Dec 03, 2024, $*****
- Highlight: Editors' Pick
2. Lively
Health saving account to save for healthcare expenses. The investments are tax-free, and users can invest from the first day with no minimum balance requirement. HSA customers can invest their HSA funds in ETFs, stocks, bonds, or mutual funds--any securities that are available on the TD Ameritrade platform.
Key facts about Lively
- Founded Year: 2016
- Location: San Francisco (United States)
- Stage: Series C
- Total Funding till date: $122M
- Employee Count: 170 as on Jul 31, 2026
- Investors: B Capital, Teamworthy Ventures and 21 Others
- Latest Funding Round: Series C, Oct 13, 2021, $*****
- Highlight: Editors' Pick
3. Castelion
It is a modern defense production company that specializes in building advanced military hypersonic, vehicle, and strike systems for future war deterrence. They apply modern hardware development and manufacturing processes to address national security challenges.
Key facts about Castelion
- Founded Year: 2022
- Location: El Segundo (United States)
- Valuation: $*****
- Stage: Series C
- Total Funding till date: $1.3B
- Employee Count: 232 as on Jul 31, 2026
- Investors: T. Rowe Price, Summit Partners and 22 Others
- Latest Funding Round: Series C, Aug 19, 2026, $*****
- Highlight: Editors' Pick
4. Twelve
Developer of carbon transformation technology producing fuels and feedstock products. The company's technology transforms carbon dioxide, water, and renewable electricity into hydrocarbons. These hydrocarbons are drop-in replacements for conventional petroleum-based materials and ingredients. The resulting products have zero fossil fuels, zero emissions, and no trade-offs in quality.
Key facts about Twelve
- Founded Year: 2015
- Location: Berkeley (United States)
- Stage: Series C
- Total Funding till date: $472M
- Employee Count: 268 as on Jul 31, 2026
- Investors: Rising Tide Fund, Shell and 55 Others
- Latest Funding Round: Series C, May 06, 2025, $*****
- Highlight: Editors' Pick
5. SkyRyse
Developer of advanced flight automation systems for aircraft. It offers a fully digitized aircraft operating system enhancing safety and enabling optionally-piloted capabilities. The system provides a seamless user interface, maintains stability, improves operation in low-visibility conditions, and offers automated emergency management. It also allows for ground-based control of fleets and facilitates upgrades to existing aircraft, reducing weight and maintenance costs. The system is designed to simplify controls, improve pilot safety, and maximize aircraft performance.
Key facts about SkyRyse
- Founded Year: 2016
- Location: Hayward (United States)
- Valuation: $*****
- Stage: Series C
- Total Funding till date: $605M
- Employee Count: 207 as on Jul 31, 2026
- Investors: ArrowMark Partners, Fidelity Investments and 37 Others
- Latest Funding Round: Series C, Sep 16, 2025, $*****
- Highlight: Editors' Pick
Cantos Ventures' Year-on-Year Investment Trends
Cantos Ventures has invested in 71 companies over the last 9 years, with an average of 5 new investments annually in the last 5 years. In 2025, it made 9 investments. Its most recent first time investment was in Adaptyx Biosciences and most recent follow-on round was in Faeth Therapeutics.Year | No. of Investments | ||
|---|---|---|---|
1st Round | Follow-on | Total | |
2026 (YTD) | 0 | 0 | 0 |
2025 | 5 | 4 | 9 |
2024 | 5 | 1 | 6 |
2023 | 5 | 3 | 8 |
2022 | 5 | 2 | 7 |
2021 | 7 | 2 | 9 |
2020 | 1 | 1 | 2 |
2019 | 0 | 2 | 2 |
2018 | 6 | 0 | 6 |
2017 | 3 | 0 | 3 |
Cantos Ventures' Investments by Stage
Cantos Ventures has made 24 investments in Seed stage with an average round size of $7.74M and 13 investments in Series A stage with an average round size of $18.9M.Stage of entry | No. of Investments |
|---|---|
Seed | 24 |
Series A | 13 |
Note: We have considered here, only first round of investments
Cantos Ventures' Investments by Sector
Cantos Ventures has a diverse portfolio, with companies operating in the High Tech, Life Sciences, Enterprise Applications, Sustainability Tech and HealthTech. Notably, it has invested in 63 Tech companies, 57 Enterprise (B2B) companies, 25 Software companies and at least 19 companies focusing on Tech hardware.Sector | No. of Investments |
|---|---|
High Tech | 14 |
Life Sciences | 10 |
Enterprise Applications | 7 |
Sustainability Tech | 6 |
HealthTech | 5 |
Others | 43 |
Note: We have considered here, only first round of investments
Cantos Ventures' Investments by Geography
Cantos Ventures has made most investments in United States (34), followed by Canada where it has made 2 investments.Country | No. of Investments |
|---|---|
United States | 34 |
Canada | 2 |
United Kingdom | 1 |
Note: We have considered here, only first round of investments
Cantos Ventures' recent investments
Cantos Ventures has not made any investment in 2026 so far.Here are the most recent investments by Cantos Ventures:
Filter this listDate | Company | Location | Round Details | Round Amount | Co-Investors |
|---|---|---|---|---|---|
Oct 20, 2025 | United States | Seed | 8862 | [+7] | |
Sep 18, 2025 | United States | Seed | 5993 | ||
Aug 01, 2025 | United States | Series A | 9785 | [+7] | |
Jul 03, 2025 | United States | Series B | 3157 | ||
Jun 23, 2025 | United States | Seed | 7225 | [+4] |
Unicorns in Cantos Ventures' Portfolio
Cantos Ventures has 6 unicorns in its portfolio - SkyRyse, Radiant Nuclear, Castelion and others. The most recent unicorn in their portfolio is SkyRyse. It became a unicorn in 2026, 7 years after Cantos Ventures first invested in it.Here is a list of unicorns in Cantos Ventures' portfolio:
Tracxn Score | Company | Short Description | Founded year | Sector | Location | Company Stage | First Investment/ Acquisition Details |
|---|---|---|---|---|---|---|---|
65 | Developer of advanced flight automation systems for aircraft | 2016 | Hayward | Series C | gguefdq | ||
60 | Provider of portable nuclear microreactor solutions | 2019 | Los Angeles | Series D | msaaolt | ||
66 | Defense company applying modern hardware development and manufacturing processes to national security challenges | 2022 | El Segundo | Series C | gjuzswv | ||
63 | Developer of industrial solutions for oil and gas, fuels, and defense | 2016 | Houston | Series D | vyjtiro | ||
65 | Developer of satellite-based communication services | 2015 | San Francisco | Series E | {sowp{y |
Acquired companies in Cantos Ventures' Portfolio
9 companies from Cantos Ventures' portfolio have been acquired. The most recent acquisition was Faeth Therapeutics in Feb 2026 by Sensei Biotherapeutics for $*****.Here are Cantos Ventures' portfolio companies that got acquired most recently:
Company | Acquisition Date | First Invested on | First Round of Investment | Round Size |
|---|---|---|---|---|
Feb 18, 2026 | Jan 18, 2022 | Seed | 3598 | |
Apr 24, 2025 | Jan 12, 2022 | Series A | 8836 | |
Nov 02, 2022 | - | - | 5582 | |
Sep 22, 2022 | - | - | 9459 | |
May 26, 2022 | Apr 03, 2018 | Series A | 7780 |
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Team profile of Cantos Ventures
Cantos Ventures has a team of 8 members including 5 Partners located in United States. Cantos Ventures' team does not sit on the board of any company as of now.Here is a list of all team members in Cantos Ventures:
Name | Designation | Location | Board Memberships | Contact Details |
|---|---|---|---|---|
Partner | San Francisco | - | - | |
Partner | San Francisco | - | - | |
Partner | United States | - | ||
Partner | United States | - | ||
Partner | United States | - | - |
Co-investors of Cantos Ventures
Over the past 9 years, 355 investors have co-invested in Cantos Ventures's portfolio companies. This includes funds and angels.
- Invested before Cantos Ventures: Y Combinator, National Science Foundation and 45 others have invested in rounds before Cantos Ventures. There are 4 companies where Y Combinator has invested before Cantos Ventures and 2 companies where National Science Foundation has invested before Cantos Ventures.
- Top Co-investors of Cantos Ventures: 169 investors entered a company along with Cantos Ventures. These include investors like Refactor Capital (3 companies).
- Invested after Cantos Ventures: A total of 139 investors have invested in Cantos Ventures's portfolio after their investments. Top Investors include Interlagos (2 companies), Mantis VC (2 companies) and Founders Fund (2 companies).
Recent News related to Cantos Ventures
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Heaviside Industries Emerges from Stealth with $28M Series AYahoo•May 11, 2026•Interlagos, Flume Ventures, Anorak Ventures, Cantos Ventures and 1 other
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Castelion Corp has filed a notice of an exempt offering of securities to raise $359,998,733.00 in New Funding.intelligence360•Dec 02, 2025•Castelion, SpaceX, Space VC, Champion Hill Ventures and 10 others
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Faeth nets $25M for endometrial cancer study.Endpoints•Oct 19, 2025•Faeth Therapeutics, S2G Investments, Avicella Capital, B Capital and 6 others
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Remedy Scientific Secures $11M Seed Funding for Environmental Remediation AutomationFinSMEs•Apr 10, 2025•Remedy Scientific, Refactor Capital, Cantos Ventures, BoxGroup and 1 other
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