About Lewis & Clark Agrifood
Lewis & Clark Agrifood is a venture capital firm located in St. Louis, United States. As of Oct 2024, Lewis & Clark Agrifood has invested in 24 companies. It primarily invests in Series B round in United States based startups. Its investments are spread across a wide range of sectors from Food and Agriculture Tech to Enterprise Applications and High Tech. Most recently it participated in the $***** Series B round of AgroSpheres Overall, Lewis & Clark Agrifood portfolio has seen 1 IPO and 2 acquisitions, namely GreenLight Biosciences, Growers and Aker. A lot of funds co-invest with Lewis & Clark Agrifood, with names like iSelect Fund sharing a substantial percentage of its portfolio. Lewis & Clark Agrifood has team of 15 people including 5 partners.Key Metrics
Team Members
Portfolio Count
Portfolio Sectors
Portfolio Locations
Rounds of Entry
Series A, Series B & 4 more
Portfolio IPOs
Portfolio Soonicorns
Lewis & Clark Agrifood's List of Top Investments
Lewis & Clark Agrifood has a portfolio of 24 companies. Their most notable investments are in AgroSpheres and Beta Hatch.Their portfolio spans across United States and Canada. They have invested in Food and Agriculture Tech, Enterprise Applications, High Tech and 8 other sectors, across stages such as Series A, Series B and 4 more. Here is the list of top investments by Lewis & Clark Agrifood:
1. Brightseed
Provider of AI based platform to discover plant bio actives for human health. It offers a proprietary AI and computational biology platform called Forager which is used to map plant metabolomes, predict bioactive-compound and receptor interactions, and accelerate discovery and validation. The platform find molecules in plants, fungi, microbes and others. that have beneficial biological effects, and then turning those into ingredients for food, supplement, or health companies.
Key facts about Brightseed
- Founded Year: 2018
- Location: San Francisco (United States)
- Stage: Series B
- Total Funding till date: $120M
- Employee Count: 37 as on Aug 31, 2026
- Investors: Temasek, iSelect Fund and 14 Others
- Latest Funding Round: Series B, May 09, 2022, $*****
- Highlight: Editors' Pick
2. BinSentry
Provider of AI-powered feed management system optimizing animal feed supply chains. It provide solutions for feed mill operators and producers offering real-time monitoring and automation through advanced sensors and a user-friendly dashboard. The technology helps reduce trucking costs, labor, feed reclaims, and outages. It offers a subscription service with lifetime hardware warranty and comprehensive support, including installation, training, and data analytics. It focuses on improving animal health, employee safety, and feed conversion ratios, enabling efficient feed ordering and problem-solving.
Key facts about BinSentry
- Founded Year: 2017
- Location: Kitchener (Canada)
- Stage: Series C
- Total Funding till date: $74.2M
- Employee Count: 103 as on Sep 30, 2026
- Investors: Lead Edge Capital, Spring Mountain Capital and 6 Others
- Latest Funding Round: Conventional Debt, Dec 19, 2025, $*****
- Highlight: Editors' Pick
Developer of biological technologies for improved crop input performance. The company focuses on PPFMs to enhance plant development and defense. Technologies are applied as planter box applications or seed treatments. The company offers bioinsecticide, biofungicide, and biostimulant technologies. These technologies aim to help crops reach their full potential.
Key facts about NewLeaf Symbiotics
- Founded Year: 2011
- Location: St. Louis (United States)
- Stage: Series D
- Total Funding till date: $181M
- Employee Count: 47 as on Sep 30, 2026
- Investors: Bayer, Monsanto and 13 Others
- Latest Funding Round: Series D, Dec 12, 2023, $*****
- Highlight: Editors' Pick
4. BlueNalu
Produces and supplies seafood products using fish cells. Its product offerings include finned fish, crustaceans, and mollusks. The company's products are developed by isolating living cells from fish tissue which is placed into a culture media for proliferation and then assembled. The company claims its products are serum-free. The company supplies its products to CPG product companies, the food service & retail industry, and food processors.
Key facts about BlueNalu
- Founded Year: 2017
- Location: San Diego (United States)
- Valuation: $*****
- Stage: Series B
- Total Funding till date: $129M
- Employee Count: 35 as on Sep 30, 2026
- Investors: Sumitomo, New Crop Capital and 40 Others
- Latest Funding Round: Series B, Dec 29, 2025, $*****
- Highlight: Editors' Pick
5. Arzeda
Developer of enzyme design technology to bridge the gap by creating synthetic enzymes. The proprietary technology combines targeted computational enzyme design and protein optimization with metabolic bioengineering to create entirely novel designer cell factories capable of industry-scale chemical production.
Key facts about Arzeda
- Founded Year: 2008
- Location: Seattle (United States)
- Stage: Series B
- Total Funding till date: $95.2M
- Employee Count: 79 as on Sep 30, 2026
- Investors: Washington Research Foundation, Washington Research Foundation and 22 Others
- Latest Funding Round: Series B, Aug 28, 2025, $*****
- Highlight: Editors' Pick
Lewis & Clark Agrifood's Year-on-Year Investment Trends
Lewis & Clark Agrifood has invested in 24 companies over the last 9 years, with an average of 2 new investments annually in the last 5 years. Its most recent first time investment was in Lingrove and most recent follow-on round was in AgroSpheres.Year | No. of Investments | ||
|---|---|---|---|
1st Round | Follow-on | Total | |
2026 (YTD) | 0 | 0 | 0 |
2025 | 0 | 0 | 0 |
2024 | 0 | 1 | 1 |
2023 | 2 | 2 | 4 |
2022 | 4 | 2 | 6 |
2021 | 8 | 0 | 8 |
2020 | 4 | 1 | 5 |
2019 | 1 | 1 | 2 |
2018 | 1 | 1 | 2 |
2017 | 3 | 1 | 4 |
Lewis & Clark Agrifood's Investments by Stage
Lewis & Clark Agrifood has made 9 investments in Series A stage with an average round size of $16.7M, 8 investments in Series B stage with an average round size of $27.2M and 2 investments in Series C stage with an average round size of $35.5M.Stage of entry | No. of Investments |
|---|---|
Series A | 9 |
Series B | 8 |
Series C | 2 |
Series D | 2 |
Conventional Debt | 1 |
Others | 1 |
Note: We have considered here, only first round of investments
Lewis & Clark Agrifood's Investments by Sector
Lewis & Clark Agrifood has a diverse portfolio, with companies operating in the Food and Agriculture Tech, Sustainability Tech, High Tech, Enterprise Applications and Environment Tech. Notably, it has invested in 22 Tech companies, 21 Enterprise (B2B) companies, 12 Software companies and at least 4 companies focusing on Consumer (B2C).Sector | No. of Investments |
|---|---|
Food and Agriculture Tech | 14 |
Sustainability Tech | 13 |
High Tech | 11 |
Enterprise Applications | 8 |
Environment Tech | 6 |
Others | 22 |
Note: We have considered here, only first round of investments
Lewis & Clark Agrifood's Investments by Geography
Lewis & Clark Agrifood has made most investments in United States (22), followed by Canada where it has made 1 investment.Country | No. of Investments |
|---|---|
United States | 22 |
Canada | 1 |
Note: We have considered here, only first round of investments
Lewis & Clark Agrifood's recent investments
Lewis & Clark Agrifood has not made any investment in 2026 so far.Here are the most recent investments by Lewis & Clark Agrifood:
Filter this listDate | Company | Location | Round Details | Round Amount | Co-Investors |
|---|---|---|---|---|---|
Oct 02, 2024 | United States | Series B | 4736 | [+4] | |
Dec 18, 2023 | United States | Series B | 2281 | ||
Oct 27, 2023 | United States | Series B | 8457 | [+6] | |
Aug 22, 2023 | United States | Series C | 9621 | [+6] | |
Feb 23, 2023 | United States | Series D | 7438 | [+3] |
IPOs and Publicly Listed companies in Lewis & Clark Agrifood's Portfolio
1 of Lewis & Clark Agrifood's portfolio company became public - GreenLight Biosciences. It got listed on the National Association of Securities Dealers Automated Quotations (NASDAQ), in Feb 2022 at marketcap of $44.9MHere are Lewis & Clark Agrifood's portfolio companies that went public:
Company | IPO Date | First Invested on | First Round of Investment | Round Size |
|---|---|---|---|---|
Feb 03, 2022 | Sep 14, 2017 | Series D | 8516 |
Acquired companies in Lewis & Clark Agrifood's Portfolio
2 companies from Lewis & Clark Agrifood's portfolio have been acquired. The most recent acquisition was Aker in Apr 2023 by IntelinAir for $*****.Here are Lewis & Clark Agrifood's portfolio companies that got acquired most recently:
Company | Acquisition Date | First Invested on | First Round of Investment | Round Size |
|---|---|---|---|---|
Apr 04, 2023 | Aug 27, 2019 | Seed | 4898 | |
Feb 19, 2020 | Sep 12, 2018 | Series A | 3406 |
Team profile of Lewis & Clark Agrifood
Lewis & Clark Agrifood has a team of 15 members including 5 Partners located in United States. Lewis & Clark Agrifood's team does not sit on the board of any company as of now.Here is a list of top team members in Lewis & Clark Agrifood:
Name | Designation | Location | Board Memberships | Contact Details |
|---|---|---|---|---|
Partner | Saint Louis | - | - | |
Partner | United States | - | - | |
Partner | United States | - | - | |
Partner | United States | - | - | |
Partner | United States | - | - |
Co-investors of Lewis & Clark Agrifood
Over the past 9 years, 258 investors have co-invested in Lewis & Clark Agrifood's portfolio companies. This includes only funds.
- Invested before Lewis & Clark Agrifood: America’s Seed Fund, National Science Foundation and 130 others have invested in rounds before Lewis & Clark Agrifood. There are 6 companies where America’s Seed Fund has invested before Lewis & Clark Agrifood and 5 companies where National Science Foundation has invested before Lewis & Clark Agrifood.
- Top Co-investors of Lewis & Clark Agrifood: 61 investors entered a company along with Lewis & Clark Agrifood. These include investors like iSelect Fund (3 companies).
- Invested after Lewis & Clark Agrifood: A total of 65 investors have invested in Lewis & Clark Agrifood's portfolio after their investments. Top Investors include Lewis & Clark Partners (3 companies), Bayer (2 companies) and Sofinnova Partners (2 companies).
Recent News related to Lewis & Clark Agrifood
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Seattle startup Arzeda raises $38M to create proteins for food, pharma, and other industriesGeekWire•Sep 17, 2024•Arzeda, Sofinnova Partners, Fall Line Capital, Sucden and 5 others
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St. Louis investor raises $70M for new fundThe Business Journals•Dec 27, 2023•Lewis & Clark Agrifood
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Lingrove, makers of plant-based composites, secures $10 million to ramp up productionWoodworking Network•Dec 18, 2023•Lingrove, Lewis & Clark Agrifood, Diamond Edge Ventures, SOSV and 1 other
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AgroSpheres Banks Expansion of $25M Series BiGrow News•Nov 28, 2023•AgroSpheres, FMC, Lewis & Clark Agrifood, Ospraie Ag Science and 2 others
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Bushel Raises $26M in FundingFinSMEs•Aug 23, 2023•Bushel, The Banc Funds, 50 South Capital, The Andersons and 4 others
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P2 Science Raises Funding RoundFinSMEs•Feb 24, 2023•P2 Science, Lewis & Clark Agrifood, HG Ventures, Elm Street Ventures and 3 others
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Leader In Plant-based Indigo, Stony Creek Colors, Closes $4.8 Million Series B2 Funding Round To Scale Natural Dye OperationsPR Newswire•Dec 01, 2022•Lewis & Clark Agrifood, Levi Strauss, Stony Creek Colors, AGRI FOOD PRODUCTS
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AgroSpheres Closes $22M Series B for Bio-Based Crop SolutionsGlobal AgInvesting•Oct 26, 2022•AgroSpheres, Lewis & Clark Agrifood, Ospraie Ag Science, Bidra Innovation Ventures and 1 other
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Brightseed’s $68 Million Series B FinancingGlobal Legal Chronicle•May 17, 2022•Brightseed, Temasek, Lewis & Clark Agrifood, S2G Ventures and 3 others
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Natural Fiber Welding raises $85 millionBiofuels Digest•Apr 19, 2022•Natural Fiber Welding, Evolution VC Partners, Tattarang, Lewis & Clark Agrifood and 11 others
