About Main Sequence
Main Sequence is a venture capital firm founded in 2017. It is primarily based out of North Ryde, Australia. As of Aug 2026, Main Sequence is an active investor, having invested in 61 companies, with 4 new investments in the last 12 months. It primarily invests in Series A round in Australia based startups. Its investments are spread across a wide range of sectors from High Tech to Enterprise Applications and Food and Agriculture Tech. Most recently it participated in the $***** Seed round of Zabidou A lot of funds co-invest with Main Sequence, with names like Horizons Ventures sharing a substantial percentage of its portfolio. Main Sequence has team of 13 people including 2 partners.Key Metrics
Team Members
Portfolio Count
Portfolio Sectors
Portfolio Locations
Rounds of Entry
Seed, Series A & 2 more
Main Sequence's List of Top Investments
Main Sequence has a portfolio of 61 companies. Their most notable investments are in v2food and Q-Ctrl.Their portfolio spans across Australia, United States and United Kingdom. They have invested in High Tech, Enterprise Applications, Food and Agriculture Tech and 23 other sectors, across stages such as Seed, Series A and 2 more. Here is the list of top investments by Main Sequence:
Provider of quantum cybersecurity solutions, including key management and distribution. It delivers data protection through quantum key generation and crypto-agile key management. The company offers quantum key distribution, helping organizations build a quantum-safe future. Its capabilities extend to quantum true random number generators and entropy management software.
Key facts about QuintessenceLabs
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2. Q-Ctrl
Developer of cloud-based firmware to stabilise qubits from quantum decoherence. The technology uses engineering-inspired transfer functions to provide realistic error budgeting and closed-loop control stabilisation techniques for mitigating hardware errors. It also provides advanced control protocols to reconstruct sensor features and provide quantum clock stabilisation.
Key facts about Q-Ctrl
- Founded Year: 2017
- Location: Sydney (Australia)
- Stage: Series B
- Total Funding till date: $166M
- Employee Count: 208 as on Jun 30, 2026
- Investors: Mindrock Capital, GP Bullhound and 24 Others
- Latest Funding Round: Series B, Oct 08, 2024, $*****
- Highlight: Editors' Pick
3. Amber
Provider of energy solutions for home batteries, solar, and EVs. It offers tools to manage energy consumption, including battery automation technology. The company provides access to wholesale electricity prices and feed-in rates. It also offers resources such as solar and battery calculators, compatibility checks, and expert consultations.
Key facts about Amber
- Founded Year: 2017
- Location: Melbourne (Australia)
- Stage: Series D
- Total Funding till date: $104M
- Employee Count: 212 as on Jun 30, 2026
- Investors: ETF Partners, Virescent Ventures and 19 Others
- Latest Funding Round: Series D, Oct 01, 2025, $*****
- Highlight: Editors' Pick
4. Every
Brand of vegan products. Its product portfolio includes vegan protein drink, vegan bakery products, vegan chocolate chip baking mix, and more. It provides alternatives to traditional animal-derived proteins. The company focuses on innovation in food technology, aiming to create delicious and nutritious food products that cater to modern dietary preferences.
Key facts about Every
- Founded Year: 2014
- Location: Daly City (United States)
- Stage: Series D
- Total Funding till date: $285M
- Employee Count: 153 as on Jun 30, 2026
- Investors: Prosus, Temasek and 26 Others
- Latest Funding Round: Series D, Nov 04, 2025, $*****
- Highlight: Editors' Pick
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5. Morse Micro
Provider of WiFi chips to enable IoT applications. Its connectivity platform is a single-chip solution, each of which incorporates the Radio, PHY, and MAC sections.
Key facts about Morse Micro
- Founded Year: 2016
- Location: Sydney (Australia)
- Stage: Series C
- Total Funding till date: $208M
- Employee Count: 200 as on Jun 30, 2026
- Investors: Hostplus, Right Click Capital and 24 Others
- Latest Funding Round: Series C, Sep 22, 2025, $*****
- Highlight: Editors' Pick
Main Sequence's Year-on-Year Investment Trends
Main Sequence has invested in 61 companies over the last 9 years, with an average of 6 new investments annually in the last 5 years. In 2025, it made 13 investments, while as of Aug 2026, it has made 12 investments in this year. Its most recent first time investment was in Zabidou and most recent follow-on round was in Emesent.Year | No. of Investments | ||
|---|---|---|---|
1st Round | Follow-on | Total | |
2026 (YTD) | 2 | 10 | 12 |
2025 | 5 | 8 | 13 |
2024 | 4 | 7 | 11 |
2023 | 8 | 8 | 16 |
2022 | 8 | 7 | 15 |
2021 | 7 | 7 | 14 |
2020 | 2 | 5 | 7 |
2019 | 9 | 5 | 14 |
2018 | 5 | 1 | 6 |
2017 | 5 | 0 | 5 |
Main Sequence's Investments by Stage
Main Sequence has made 25 investments in Seed stage with an average round size of $3.44M, 22 investments in Series A stage with an average round size of $12.9M, 7 investments in Series B stage with an average round size of $30.9M and 1 investment in Series C stage with an average round size of $19.1M.Stage of entry | No. of Investments |
|---|---|
Seed | 25 |
Series A | 22 |
Series B | 7 |
Series C | 1 |
Note: We have considered here, only first round of investments
Main Sequence's Investments by Sector
Main Sequence has a diverse portfolio, with companies operating in the High Tech, Enterprise Applications, Sustainability Tech, Environment Tech and Food and Agriculture Tech. Notably, it has invested in 52 Tech companies, 47 Enterprise (B2B) companies, 31 Software companies and at least 21 companies focusing on Tech hardware.Sector | No. of Investments |
|---|---|
High Tech | 28 |
Enterprise Applications | 23 |
Sustainability Tech | 13 |
Environment Tech | 8 |
Food and Agriculture Tech | 8 |
Others | 64 |
Note: We have considered here, only first round of investments
Main Sequence's Investments by Geography
Main Sequence has made most investments in Australia (46), followed by United States where it has made 6 investments.Country | No. of Investments |
|---|---|
Australia | 46 |
United States | 6 |
United Kingdom | 1 |
Note: We have considered here, only first round of investments
Main Sequence's recent investments
Main Sequence has made 12 investments in 2026 so far. Zabidou and Emesent are the latest among them.Here are the most recent investments by Main Sequence:
Filter this listDate | Company | Location | Round Details | Round Amount | Co-Investors |
|---|---|---|---|---|---|
Aug 04, 2026 | - | Seed | 8474 | [+1] | |
Jul 02, 2026 | Australia | Series A | 8270 | [+3] | |
May 15, 2026 | Australia | Series A | 8970 | [+4] | |
Apr 29, 2026 | Australia | Seed | 5294 | - | |
Apr 14, 2026 | Australia | Seed | 8686 | [+4] |
Team profile of Main Sequence
Main Sequence has a team of 13 members including 2 Partners, 2 Venture Partners and 3 Principals located in Australia. Main Sequence's team does not sit on the board of any company as of now.Here is a list of top team members in Main Sequence:
Name | Designation | Location | Board Memberships | Contact Details |
|---|---|---|---|---|
Partner | Sydney | - | ||
Partner | Sydney | - | ||
Venture Partner | Sydney | - | - | |
Venture Partner | The Rocks | - | ||
Principal | Adelaide | - | ||
Principal | Brisbane | - | ||
Principal | Australia | - |
Co-investors of Main Sequence
Over the past 9 years, 364 investors have co-invested in Main Sequence's portfolio companies. This includes funds and angels.
- Invested before Main Sequence: Blackbird Ventures, Grok Ventures and 70 others have invested in rounds before Main Sequence. There are 3 companies where Blackbird Ventures has invested before Main Sequence and 3 companies where Grok Ventures has invested before Main Sequence.
- Top Co-investors of Main Sequence: 98 investors entered a company along with Main Sequence. These include investors like Horizons Ventures (4 companies).
- Invested after Main Sequence: A total of 194 investors have invested in Main Sequence's portfolio after their investments. Top Investors include National Reconstruction Fund (8 companies), CSIRO (6 companies) and NGS Super (6 companies).
Recent News related to Main Sequence
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Australian Quantum Sensor Company Deteqt Raises A$5 Million Seed FundingMarinelink•May 21, 2026•Deteqt, Main Sequence
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Aigentsphere Raises $4 Million Seed Round for AI Governance SystemStartup Daily•Apr 29, 2026•Main Sequence, Aigentsphere
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Deteqt nabs $5M to scale quantum diamond chips for defence and mineral sensingStartup Daily•Apr 14, 2026•Deteqt, ATP, Main Sequence, BOKA Capital
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Arlula Raises $3.4m for its EO AmbitionsSpatial Source•Mar 25, 2026•Startmate, Arlula, Paspalis, Main Sequence
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Cauldron Raises $13.25M in Series A2 FundingFinSMEs•Mar 24, 2026•Cauldron, NGS Super, Main Sequence, SOSV and 3 others
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Thermal Energy Storage Company MGA Thermal Secures $12 MillionMercom Capital•Mar 16, 2026•MGA Thermal, Main Sequence, IP Group
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MGA Thermal Raises $17 Million to Supercharge Renewable Heat StorageStartup Daily•Mar 13, 2026•MGA Thermal, Main Sequence, IP Group
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Australian start-up Breaker raises A$9 million in seed fundingAsia Pacific Defence Reporter•Feb 17, 2026•Breaker, Main Sequence, Bessemer Venture Partners, Alpha Design AI and 4 others
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Kasada Raises $20 Million for Anti-Bot ExpansionSecurityWeek•Feb 03, 2026•Kasada, The Stepstone Group, OIF Ventures, EQT and 3 others
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