About NexPoint
NexPoint is a venture capital firm founded in 1993. It is primarily based out of Dallas, United States. As of Feb 2024, NexPoint has invested in 4 companies. It primarily invests in Seed round in United States based startups. Its investments are spread across a wide range of sectors from Life Sciences to Enterprise Applications and Financial Services. Most recently it participated in the $***** Seed round of PlantSwitch Overall, NexPoint portfolio has seen 1 IPO, namely Apnimed. A lot of funds co-invest with NexPoint, with names like Alpha Wave Global sharing a substantial percentage of its portfolio. NexPoint has team of 81 people including 23 partners.Key Metrics
Team Members
Portfolio Count
Portfolio Sectors
Portfolio Locations
Rounds of Entry
Seed, Series B & 1 more
Portfolio IPOs
NexPoint's List of All Investments
NexPoint has a portfolio of 4 companies. Their most notable investments are in Sapience Therapeutics and PlantSwitch.Their portfolio spans across and United States. They have invested in Life Sciences, Enterprise Applications, Financial Services, across Seed, Series B and 1 more. Here is the list of all investments by NexPoint:
1. Apnimed
Developer of small molecule-based therapeutics for the treatment of obstructive sleep apnea. The company has developed a combination of Atomoxetine and Oxybutynin which reduces the obstructive sleep apnea severity. It targets the neurological control and activation of upper airway dilator muscles which improve respiration and oxygenation during sleep.
Key facts about Apnimed
- Founded Year: 2017
- Location: Cambridge (United States)
- Stage: Public
- Total Funding till date: $249M
- Employee Count: 92 as on Jun 30, 2026
- Investors: Sectoral, Alpha Wave Global and 6 Others
- Latest Funding Round: Conventional Debt, Apr 07, 2026, $*****
- Highlight: Public
Pioneering peptide therapeutics for traditionally undruggable cancer targets. This is a biopharmaceutical company focused on redefining druggability in oncology through innovative peptide therapeutics. They are developing SPEARs and SPARCs, acting inside and outside cancer cells, respectively. The company's pipeline includes first-in-class therapeutics targeting protein-protein interactions, with programs in Phase clinical trials. They are committed to delivering precision therapy and hope to patients and their families by targeting traditionally elusive oncogenic proteins. The company is involved in drug discovery, preclinical development, and clinical trials, aiming to create novel cancer treatments. They are leveraging peptide technology to develop targeted therapies for solid tumors and hematological diseases. The company is focused on research and development, clinical data presentation, and participation in healthcare conferences.
Key facts about Sapience Therapeutics
- Founded Year: 2015
- Location: Scarsdale (United States)
- Stage: Series B
- Total Funding till date: $71.5M
- Employee Count: 24 as on Jun 30, 2026
- Investors: Celgene, Kingdon Capital Management and 7 Others
- Latest Funding Round: Grant (prize money), Aug 14, 2025, $*****
- Highlight: Editors' Pick

3. PlantSwitch
Manufacturer of compostable plant based resin and food service products. This business converts agricultural residues into bio-resin pellets for use in plastic manufacturing equipment. The resulting material serves as a substitute for petroleum-based plastics in the production of items such as cups, lids, cutlery, and straws. These products are designed to biodegrade in home composting environments. The process utilizes agricultural byproducts to create materials that function as drop-in replacements for conventional plastic manufacturing.
Key facts about PlantSwitch
- Founded Year: 2020
- Location: Dallas (United States)
- Stage: Series A
- Total Funding till date: $40.7M
- Employee Count: 22 as on Jun 30, 2026
- Investors: NexPoint and United States Department of Agriculture
- Latest Funding Round: Series A, May 22, 2026, $*****
4. UDFIV
Real estate investment firm focused on development funding and income generation. The company manages investment funds, providing opportunities for investors. It focuses on real estate development projects, aiming to generate income through strategic investments. The firm is involved in various legal proceedings and provides updates to investors. It offers news and resources for investors, maintaining communication through investor and media relations channels. The company is committed to transparency and compliance, adhering to terms of use and privacy policies.
Key facts about UDFIV
- Founded Year: 2009
- Location: Grapevine (United States)
- Annual Revenue: $10M - $50M as on Dec 31, 2011
- Stage: Seed
- Employee Count: 1 as on Jun 30, 2026
- Investors: NexPoint
- Latest Funding Round: Seed, Apr 13, 2021, $*****
NexPoint's Year-on-Year Investment Trends
NexPoint has invested in 5 companies over the last 5 years, with an average of 1 new investment annually in the last 5 years. Its most recent first time investment was in PlantSwitch and most recent follow-on round was in PlantSwitch.Year | No. of Investments | ||
|---|---|---|---|
1st Round | Follow-on | Total | |
2026 (YTD) | 0 | 0 | 0 |
2025 | 0 | 0 | 0 |
2024 | 0 | 1 | 1 |
2023 | 1 | 0 | 1 |
2022 | 2 | 0 | 2 |
2021 | 1 | 0 | 1 |
NexPoint's Investments by Stage
NexPoint has made 2 investments in Seed stage with an average round size of $2M, 1 investment in Series B stage with an average round size of $41M and 1 investment in Series C stage with an average round size of $62.5M.Stage of entry | No. of Investments |
|---|---|
Seed | 2 |
Series B | 1 |
Series C | 1 |
Note: We have considered here, only first round of investments
NexPoint's Investments by Sector
NexPoint has a diverse portfolio, with companies operating in the Life Sciences, Enterprise Applications and Financial Services. Notably, it has invested in 2 Enterprise (B2B) companies, 2 Tech companies and 1 Software company.Sector | No. of Investments |
|---|---|
Life Sciences | 2 |
Enterprise Applications | 1 |
Financial Services | 1 |
Note: We have considered here, only first round of investments
NexPoint's Investments by Geography
NexPoint has made most investments in United States (4).NexPoint's recent investments
NexPoint has not made any investment in 2026 so far.Here are the most recent investments by NexPoint:
Date | Company | Location | Round Details | Round Amount | Co-Investors |
|---|---|---|---|---|---|
Feb 20, 2024 | United States | Seed | 1797 | - | |
Nov 28, 2023 | United States | Seed | 3377 | - | |
Nov 01, 2022 | United States | Series C | 1492 | [+4] | |
Jun 01, 2022 | United States | Series B | 3410 | [+2] | |
Apr 13, 2021 | United States | Seed | 5714 | - |
IPOs and Publicly Listed companies in NexPoint's Portfolio
1 of NexPoint's portfolio company became public - Apnimed. It got listed on the National Association of Securities Dealers Automated Quotations (NASDAQ), in Jul 2026 at marketcap of $637MHere are NexPoint's portfolio companies that went public:
Company | IPO Date | First Invested on | First Round of Investment | Round Size |
|---|---|---|---|---|
Jul 31, 2026 | Nov 01, 2022 | Series C | 3027 |
Team profile of NexPoint
NexPoint has a team of 81 members including 23 Partners and 17 Principals located in United States. NexPoint's team does not sit on the board of any company as of now.Here is a list of top team members in NexPoint:
Name | Designation | Location | Board Memberships | Contact Details |
|---|---|---|---|---|
Partner | Dallas | - | ||
Partner | Nashville | - | ||
Partner | United States | - | ||
Partner | Dallas | - | ||
Partner | Dallas | - | ||
Partner | Dallas | - | ||
Partner | Dallas | - | ||
Partner | Dallas | - | ||
Partner | Prosper | - | - | |
Partner | Houston | - | ||
Partner | Dallas | - |
Co-investors of NexPoint
Over the past 5 years, 14 investors have co-invested in NexPoint's portfolio companies. This includes only funds.
- Invested before NexPoint: Tao Capital Partners, Morningside and 4 others have invested in rounds before NexPoint. There is 1 company where Tao Capital Partners has invested before NexPoint and 1 company where Morningside has invested before NexPoint.
- Top Co-investors of NexPoint: 5 investors entered a company along with NexPoint. These include investors like Alpha Wave Global (1 company).
- Invested after NexPoint: A total of 3 investors have invested in NexPoint's portfolio after their investments. Top Investors include Columbia-Seligman Investments (1 company), HCRx (1 company) and HHS (1 company).
Recent News related to NexPoint
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NexPoint Residential Trust, Inc. Reports Second Quarter 2026 ResultsPR Newswire•Aug 04, 2026•NexPoint
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Paul Richards Acquires 2,000 Shares of NexPoint Residential Trust (NYSE:NXRT) StockMarketBeat•Mar 12, 2026•NexPoint
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NexPoint Residential Trust (NYSE:NXRT) Insider Acquires $26,390.00 in StockMarketBeat•Mar 12, 2026•NexPoint
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NexPoint Residential Trust, Inc. Reports Fourth Quarter and Full Year 2025 ResultsPR Newswire•Feb 24, 2026•NexPoint
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