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About NexPoint

NexPoint is a venture capital firm founded in 1993. It is primarily based out of Dallas, United States. As of Feb 2024, NexPoint has invested in 4 companies. It primarily invests in Seed round in United States based startups. Its investments are spread across a wide range of sectors from Life Sciences to Enterprise Applications and Financial Services. Most recently it participated in the $***** Seed round of PlantSwitch Overall, NexPoint portfolio has seen 1 IPO, namely Apnimed. A lot of funds co-invest with NexPoint, with names like Alpha Wave Global sharing a substantial percentage of its portfolio. NexPoint has team of 81 people including 23 partners.
Key Metrics
Portfolio Locations
Rounds of Entry
Seed, Series B & 1 more
Portfolio IPOs

NexPoint's List of All Investments

NexPoint has a portfolio of 4 companies. Their most notable investments are in Sapience Therapeutics and PlantSwitch.Their portfolio spans across and United States. They have invested in Life Sciences, Enterprise Applications, Financial Services, across Seed, Series B  and 1 more. Here is the list of all investments by NexPoint:
Developer of small molecule-based therapeutics for the treatment of obstructive sleep apnea. The company has developed a combination of Atomoxetine and Oxybutynin which reduces the obstructive sleep apnea severity. It targets the neurological control and activation of upper airway dilator muscles which improve respiration and oxygenation during sleep.

Key facts about Apnimed

Pioneering peptide therapeutics for traditionally undruggable cancer targets. This is a biopharmaceutical company focused on redefining druggability in oncology through innovative peptide therapeutics. They are developing SPEARs and SPARCs, acting inside and outside cancer cells, respectively. The company's pipeline includes first-in-class therapeutics targeting protein-protein interactions, with programs in Phase clinical trials. They are committed to delivering precision therapy and hope to patients and their families by targeting traditionally elusive oncogenic proteins. The company is involved in drug discovery, preclinical development, and clinical trials, aiming to create novel cancer treatments. They are leveraging peptide technology to develop targeted therapies for solid tumors and hematological diseases. The company is focused on research and development, clinical data presentation, and participation in healthcare conferences.

Key facts about Sapience Therapeutics

Manufacturer of compostable plant based resin and food service products. This business converts agricultural residues into bio-resin pellets for use in plastic manufacturing equipment. The resulting material serves as a substitute for petroleum-based plastics in the production of items such as cups, lids, cutlery, and straws. These products are designed to biodegrade in home composting environments. The process utilizes agricultural byproducts to create materials that function as drop-in replacements for conventional plastic manufacturing.

Key facts about PlantSwitch

Real estate investment firm focused on development funding and income generation. The company manages investment funds, providing opportunities for investors. It focuses on real estate development projects, aiming to generate income through strategic investments. The firm is involved in various legal proceedings and provides updates to investors. It offers news and resources for investors, maintaining communication through investor and media relations channels. The company is committed to transparency and compliance, adhering to terms of use and privacy policies.

Key facts about UDFIV

  • Founded Year: 2009
  • Location: Grapevine (United States)
  • Annual Revenue: $10M - $50M as on Dec 31, 2011
  • Stage: Seed
  • Employee Count: 1 as on Jun 30, 2026
  • Investors: NexPoint
  • Latest Funding Round: Seed, Apr 13, 2021, $*****

NexPoint's Investments by Stage

NexPoint has made 2 investments in Seed stage with an average round size of $2M, 1 investment in Series B stage with an average round size of $41M and 1 investment in Series C stage with an average round size of $62.5M.
Here are NexPoint's investments by stage:
Stage of entry
No. of Investments
Seed
2
Series B
1
Series C
1
Breakdown of NexPoint's investments by stage of entrySeed (2)Series B (1)
Note: We have considered here, only first round of investments

NexPoint's Investments by Sector

NexPoint has a diverse portfolio, with companies operating in the Life Sciences, Enterprise Applications and Financial Services. Notably, it has invested in 2 Enterprise (B2B) companies, 2 Tech companies and 1 Software company.
Here are NexPoint's investments by sector:
Sector
No. of Investments
Life Sciences
2
Enterprise Applications
1
Financial Services
1
Breakdown of NexPoint's investments by sectorsLife Sciences (2)Enterprise Applic... (1)
Note: We have considered here, only first round of investments

NexPoint's Investments by Geography

NexPoint has made most investments in United States (4).

NexPoint's recent investments

NexPoint has not made any investment in 2026 so far.
Here are the most recent investments by NexPoint:
Date
Company
Location
Round Details
Round Amount
Co-Investors
Feb 20, 2024
United States
Seed
1797
-
Nov 28, 2023
United States
Seed
3377
-
Nov 01, 2022
United States
Series C
1492
  [+4]
Jun 01, 2022
United States
Series B
3410
Apr 13, 2021
United States
Seed
5714
-

IPOs and Publicly Listed companies in NexPoint's Portfolio

1 of NexPoint's portfolio company became public -  Apnimed. It got listed on the National Association of Securities Dealers Automated Quotations (NASDAQ), in Jul 2026 at marketcap of $637M
Here are NexPoint's portfolio companies that went public:
Company
IPO Date
First Invested on
First Round of Investment
Round Size
Jul 31, 2026
Nov 01, 2022
Series C
3027

Team profile of NexPoint

NexPoint has a team of 81 members including 23 Partners and 17 Principals located in United States. NexPoint's team does not sit on the board of any company as of now.
Here is a list of top team members in NexPoint:
Name
Designation
Location
Board Memberships
Contact Details
Partner
Dallas
-
Partner
Nashville
-
Partner
United States
-
Partner
Dallas
-
Partner
Dallas
-
Partner
Dallas
-
Partner
Dallas
-
Partner
Dallas
-
Partner
Prosper
-
-
Partner
Houston
-
Partner
Dallas
-

Co-investors of NexPoint

Over the past 5 years, 14 investors have co-invested in NexPoint's portfolio companies. This includes only funds.

  • Invested before NexPointTao Capital Partners, Morningside and 4 others have invested in rounds before NexPoint. There is 1 company where Tao Capital Partners has invested before NexPoint and 1 company where Morningside has invested before NexPoint.
  • Top Co-investors of NexPoint5 investors entered a company along with NexPoint. These include investors like Alpha Wave Global (1 company).
  • Invested after NexPointA total of 3 investors have invested in NexPoint's portfolio after their investments. Top Investors include Columbia-Seligman Investments (1 company), HCRx (1 company) and HHS (1 company).

Recent News related to NexPoint

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