About Old Silver VC
Old Silver VC is a venture capital firm founded in 2020. It primarily invests in United States based startups. Its investments are spread across a wide range of sectors from Life Sciences to High Tech and HealthTech. Overall, Old Silver VC portfolio has seen 6 IPOs and 5 acquisitions including key companies like Alnylam, Alto and Moderna. Old Silver VC has team of 3 people including 1 partners.Key Metrics
Team Members
Portfolio Sectors
Portfolio Locations
Portfolio IPOs
Portfolio Acquisitions
Portfolio Soonicorns
Old Silver VC's List of Top Investments
Old Silver VC has a portfolio of 27 companies. Their most notable investments include Alnylam and Alto.Their portfolio spans across United States and Germany. They have invested in Life Sciences, High Tech, HealthTech and 12 other sectors. Here is the list of top investments by Old Silver VC:1. Alnylam
Developer of RNA interference-based therapeutics for multiple disorders. Its pipeline includes drugs that are used to treat hereditary ATTR Amyloidosis, acute hepatic porphyria, and treating hypercholesterolemia. It also develops drugs for cardiometabolic diseases, infectious diseases, central nervous system, and ocular diseases.
Key facts about Alnylam
- Founded Year: 2002
- Location: Cambridge (United States)
- Annual Revenue: $2.25B as on Dec 31, 2024
- Stage: Public
- Total Funding till date: $17M
- Employee Count: 2,813 as on Mar 31, 2026
- Investors: Colt Ventures, BB Biotech and 13 Others
- Latest Funding Round: Post IPO, Aug 17, 2020, $*****
- Highlight: Public
_1584015723684.png?format=webp&height=120&width=120){kind=logo}
2. Alto
Online pharmacy offering prescription delivery services. The platform enables users to find and compare prices of medications and can receive over-the-counter and generic medicines at home. It also, offers platform for pharmacists for prescription management.
Key facts about Alto
- Founded Year: 2015
- Location: San Francisco (United States)
- Last Known Valuation: $*****
- Stage: Acquired
- Total Funding till date: $592M
- Employee Count: 824 as on Mar 31, 2026
- Investors: Meritech, Spur Capital and 35 Others
- Latest Funding Round: Series E, Jan 14, 2022, $*****
- Highlight: Acquired
3. Moderna
Developer of mRNA-based therapeutics for a wide range of diseases. The company produces human proteins, antibodies, or vaccines inside patient cells, which are in turn active intracellularly or secreted. The company is also developing vaccines in different disease areas such as infectious diseases, cancer, rare diseases, and COVID-19.
Key facts about Moderna
- Founded Year: 2010
- Location: Cambridge (United States)
- Annual Revenue: $3.24B as on Dec 31, 2024
- Stage: Public
- Total Funding till date: $2.78B
- Employee Count: 6,327 as on Mar 31, 2026
- Investors: ADS Ventures, Alcor Fund and 31 Others
- Latest Funding Round: Grant (prize money), Jan 17, 2025, $*****
- Highlight: Public
4. Sesame
Online platform offering multiple healthcare services. It provides a digital platform that allows users to find healthcare providers based on their needs and can schedule an appointment with them. Users can book services for men's health, baby care, women's health, mental health, diabetes care, skincare, dental health, and others. It also enables users to request a doctor for an in-person or video prescription refill and allows them to order medication from nearby pharmacies.
Key facts about Sesame
- Founded Year: 2018
- Location: New York City (United States)
- Stage: Series B
- Total Funding till date: $84.8M
- Employee Count: 142 as on Feb 28, 2026
- Investors: Industry Ventures, Old Silver VC and 11 Others
- Latest Funding Round: Series B, Sep 12, 2023, $*****
- Highlight: Editors' Pick
Developer of ophthalmic treatments based on its mucosal penetrating product platform. It offers therapies for severe ophthalmic diseases. The company’s MPP drug delivery technology platform allows therapeutic agents to pass through the mucus layer(tears) of the ocular surface, facilitating penetration into deeper tissues of the eye, including the aqueous humor and retina. Its solutions are used in treating severe ophthalmic diseases, including ocular inflammation and wet age-related macular degeneration. Its drug pipeline includes KPI-121, an ophthalmic MPP suspension in development for the treatment of post-surgical inflammation , dry eye , meibomian gland disease. Also developing MPP based topical drugs for AMD (orphan indication). It has applications in the treatment of both anterior and posterior chamber eye diseases.
Key facts about Kala Pharmaceuticals
- Founded Year: 2009
- Location: Waltham (United States)
- Annual Revenue: $3.89M as on Dec 31, 2022
- Stage: Public
- Total Funding till date: $115M
- Employee Count: 86 as on Mar 31, 2026
- Investors: Athyrium Capital Management, RA Capital Management and 17 Others
- Latest Funding Round: Post IPO, Mar 03, 2026, $*****
- Highlight: Public
IPOs and Publicly Listed companies in Old Silver VC's Portfolio
6 of Old Silver VC's portfolio companies have become public. atai Life Sciences got listed on the National Association of Securities Dealers Automated Quotations (NASDAQ), in Jun 2021 at marketcap of $2.29B and Seer got listed on the National Association of Securities Dealers Automated Quotations (NASDAQ) at marketcap of $26.3M.Here are Old Silver VC's portfolio companies that went public:
Filter this listCompany | IPO Date | First Invested on | First Round of Investment | Round Size |
|---|---|---|---|---|
Jun 18, 2021 | - | - | 9663 | |
Dec 04, 2020 | - | - | 4184 | |
Oct 03, 2019 | - | - | 7728 | |
Dec 07, 2018 | - | - | 6695 | |
Jul 20, 2017 | - | - | 6237 |
Acquired companies in Old Silver VC's Portfolio
5 companies from Old Silver VC's portfolio have been acquired. The most recent acquisition were Alto in Mar 2025 by Fuze Health.Here are Old Silver VC's portfolio companies that got acquired most recently:
Company | Acquisition Date | First Invested on | First Round of Investment | Round Size |
|---|---|---|---|---|
Mar 21, 2025 | - | - | 2058 | |
Feb 29, 2024 | - | - | 3155 | |
Jun 30, 2023 | - | - | 3814 | |
Aug 19, 2020 | - | - | 5914 | |
Dec 16, 2016 | - | - | 2366 |
_1584015723684.png?devicePixelRatio=2&height=20&width=20){kind=logo}
