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About Oxford Science Enterprises

Oxford Science Enterprises is a venture capital firm founded in 2015. It is primarily based out of Oxford, United Kingdom. As of Oct 2026, Oxford Science Enterprises is an active investor, having invested in 130 companies, with 14 new investments in the last 12 months. It primarily invests in Series A round in United Kingdom based startups. Its investments are spread across a wide range of sectors from Life Sciences to High Tech and Enterprise Applications. Most recently it participated in the $***** Series C round of OMass Therapeutics Overall, Oxford Science Enterprises portfolio has seen 3 IPOs and 14 acquisitions including key companies like Barinthus Biotherapeutics, Pepgen and Oxford Ionics. A lot of funds co-invest with Oxford Science Enterprises, with names like Oxford University Innovation sharing a substantial percentage of its portfolio. Oxford Science Enterprises has team of 41 people including 16 partners.
Key Metrics
Portfolio Count
Portfolio Sectors
Portfolio Locations
Rounds of Entry
Seed, Series A & 2 more
Portfolio Acquisitions
Portfolio Soonicorns
Deals in last 12 months

Oxford Science Enterprises' List of Top Investments

Oxford Science Enterprises has a portfolio of 130 companies. Their most notable investments are in BehaVR and Orbit Discovery.Their portfolio spans across United Kingdom, United States, Canada and 3 more locations. They have invested in Life Sciences, High Tech, Enterprise Applications and 27 other sectors, across stages such as Seed, Series A  and 2 more. Here is the list of top investments by Oxford Science Enterprises:
Provider of digital learning content and campus store management solutions. The platform offers institutions tools to automate content workflows and improve learning outcomes. It provides digital textbooks, monographs, and courseware. The platform integrates with existing systems to deliver an interactive learning experience. It supports diverse academic needs of students and faculty.

Key facts about BibliU

Developer of medical imaging software for analyzing liver disease biomarkers. This technology extracts quantitative data from magnetic resonance imaging to assist in the assessment of metabolic and chronic conditions. The software provides diagnostic information to support clinical decision-making and patient monitoring. These tools facilitate the interpretation of complex imaging data for medical professionals.

Key facts about Perspectum

  • Founded Year: 2012
  • Location: Oxford (United Kingdom)
  • Annual Revenue: £10M - £50M as on Dec 31, 2024
  • Stage: Series C
  • Total Funding till date: $140M
  • Employee Count: 279 as on Sep 30, 2026
  • Investors: Health Quest Capital, Oppenheimer and 32 Others
  • Latest Funding Round: Grant (prize money), Sep 17, 2025, $*****
  • Highlight: Editors' Pick
Developer of artificial intelligence software for analyzing cardiac ultrasound images. This technology processes echocardiogram video clips to identify patterns associated with specific heart conditions. The software integrates with existing medical imaging systems to provide automated reports for clinical review. These tools assist in the detection of heart failure and other cardiovascular abnormalities by identifying findings within routine diagnostic scans. The system functions through cloud-based infrastructure to deliver results directly into clinical workflows.

Key facts about Ultromics

4. ONI

Biotechnology company specializing in super-resolution microscopy systems. These instruments utilize single molecule localization techniques to visualize biological structures at the nanoscale. The product line includes benchtop microscopes capable of various imaging modalities such as dSTORM, PALM, and DNA-PAINT. These systems support applications in cell biology, microbiology, and nanoparticle characterization. The hardware integrates with cloud-based software platforms designed for data analysis, clustering, and collaborative research. Additionally, the company provides reagents and kits to facilitate sample labeling and preparation for high-precision imaging workflows.

Key facts about ONI

Developer of therapeutics for immunological and orphan diseases. The company's technology platform, called OdyssION, allows them to study protein assemblies and the interactions of targets within their native biological ecosystems with high resolution. The company is advancing a pipeline of small molecule therapeutics primarily for immunological and orphan diseases, using genetic and immune signature stratification to select targets with low translation risk.

Key facts about OMass Therapeutics

Oxford Science Enterprises' Investments by Stage

Oxford Science Enterprises has made 51 investments in Seed stage with an average round size of $4.96M, 31 investments in Series A stage with an average round size of $25.4M, 10 investments in Series B stage with an average round size of $33M and 1 investment in Series C stage with an average round size of $85M.
Here are Oxford Science Enterprises' investments by stage:
Stage of entry
No. of Investments
Seed
51
Series A
31
Series B
10
Series C
1
Breakdown of Oxford Science Enterprises' investments by stage of entrySeed (51)Series A (31)
Note: We have considered here, only first round of investments

Oxford Science Enterprises' Investments by Sector

Oxford Science Enterprises has a diverse portfolio, with companies operating in the Life Sciences, Enterprise Applications, High Tech, HealthTech and Sustainability Tech. Notably, it has invested in 113 Tech companies, 109 Enterprise (B2B) companies, 43 Tech hardware companies and at least 41 companies focusing on Software.
Here are Oxford Science Enterprises' investments by sector:
Sector
No. of Investments
Life Sciences
37
Enterprise Applications
28
High Tech
28
HealthTech
17
Sustainability Tech
12
Others
76
Breakdown of Oxford Science Enterprises' investments by sectorsLife Sciences (37)Enterprise Applic... (28)
Note: We have considered here, only first round of investments

Oxford Science Enterprises' Investments by Geography

Oxford Science Enterprises has made most investments in United Kingdom (77), followed by United States where it has made 9 investments.
Here are Oxford Science Enterprises' investments by geography:
Country
No. of Investments
United Kingdom
77
United States
9
Canada
1
Finland
1
Netherlands
1
Breakdown of Oxford Science Enterprises' investments by countriesUnited Kingdom (77)United States (9)
Note: We have considered here, only first round of investments

Oxford Science Enterprises' recent investments

Oxford Science Enterprises has made 20 investments in 2026 so far. OMass Therapeutics and Salience Labs are the latest among them.
Here are the most recent investments by Oxford Science Enterprises:
Date
Company
Location
Round Details
Round Amount
Co-Investors
Oct 15, 2026
United Kingdom
Series C
8862
Oct 12, 2026
United Kingdom
Series B
1402
  [+8]
Sep 15, 2026
-
Series A
9791
  [+4]
Sep 09, 2026
-
Seed
6191
Aug 17, 2026
United Kingdom
Seed
8404

IPOs and Publicly Listed companies in Oxford Science Enterprises' Portfolio

3 of Oxford Science Enterprises' portfolio companies have become public. Pepgen got listed on the National Association of Securities Dealers Automated Quotations (NASDAQ), in May 2022 at marketcap of $269M and Barinthus Biotherapeutics got listed on the National Association of Securities Dealers Automated Quotations (NASDAQ) at marketcap of $579M.
Here are Oxford Science Enterprises' portfolio companies that went public:
Company
IPO Date
First Invested on
First Round of Investment
Round Size
May 06, 2022
Nov 24, 2020
Series A
6186
Apr 30, 2021
May 12, 2016
Seed
6424
-
-
-
2999

Acquired companies in Oxford Science Enterprises' Portfolio

14 companies from Oxford Science Enterprises' portfolio have been acquired. The most recent acquisition was Brill Power in Aug 2025 by Palmer Energy Technology for $*****.
Here are Oxford Science Enterprises' portfolio companies that got acquired most recently:
Company
Acquisition Date
First Invested on
First Round of Investment
Round Size
Aug 28, 2025
Feb 17, 2021
Seed
8122
Jun 09, 2025
Jan 09, 2023
Series A
7051
Feb 18, 2025
-
-
7528
Jul 16, 2024
Jun 06, 2019
Series A
6157
Oct 20, 2022
Dec 22, 2020
Series A
5161

Team profile of Oxford Science Enterprises

Oxford Science Enterprises has a team of 41 members including 16 Partners, 4 Venture Partners and 6 Principals located in United Kingdom. Oxford Science Enterprises' team sits on the board of 4 companies.
Here is a list of top team members in Oxford Science Enterprises:
Name
Designation
Location
Board Memberships
Contact Details
Partner
United Kingdom
-
-
Partner
London
-
Partner
United Kingdom
-
-
Partner
London
-
-
Partner
United Kingdom
Mixergy, Oxford Flow and 1 more
-
Partner
United Kingdom
-
-
Partner
Bristol
-
-
Partner
London
-
-
Partner
United Kingdom
-
-

Co-investors of Oxford Science Enterprises

Over the past 11 years, 437 investors have co-invested in Oxford Science Enterprises's portfolio companies. This includes funds and angels.

  • Invested before Oxford Science Enterprises: Parkwalk, Europa and 53 others have invested in rounds before Oxford Science Enterprises. There are 8 companies where Parkwalk has invested before Oxford Science Enterprises and 5 companies where Europa has invested before Oxford Science Enterprises.
  • Top Co-investors of Oxford Science Enterprises: 179 investors entered a company along with Oxford Science Enterprises. These include investors like Oxford University Innovation (6 companies).
  • Invested after Oxford Science Enterprises: A total of 203 investors have invested in Oxford Science Enterprises's portfolio after their investments. Top Investors include Oxford (13 companies), British Business Bank (6 companies) and Oxford University Innovation (6 companies).

Recent News related to Oxford Science Enterprises

•
Living Optics Closes Funding Round of £20MinVISION News•Oct 08, 2026•Oxford Science Enterprises, Foresight Group, Octopus Ventures, Braavos and 1 other
•
MCatalysis Raises $5M in Seed FundingFinSMEs•Sep 09, 2026•Oxford Science Enterprises, MCatalysis, Hlenergyventures, Ukri
•
Oxford Spinout Mirae Secures $5.4M to Scale AI Chronic Care PlatformHIT Consultant•Jul 28, 2026•Oxford Science Enterprises
•
Vivid Dx Raises $15M to Combat Drug-Resistant InfectionsPR Newswire•Jul 28, 2026•Vivid Dx, Oxford Science Enterprises, Cedars Sinai
•
Oxford Quantum Circuits Secures Record £260m in European Quantum Computing FundingNew Electronics•Jun 03, 2026•Oqc Tech, Oxford Science Enterprises, Chevron, J P Morgan and 1 other
View all news related to Oxford Science Enterprises

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