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About Phase4 Partners

Phase4 Partners is a venture capital firm founded in 1999. It is primarily based out of London, United Kingdom. As of Apr 2015, Phase4 Partners has invested in 27 companies. It primarily invests in Post IPO round in United States based startups. Its investments are spread across a wide range of sectors from Life Sciences to High Tech and Enterprise Applications. Most recently it participated in the $***** Series B round of Nabriva Overall, Phase4 Partners portfolio has seen 6 IPOs and 12 acquisitions including key companies like Valneva, Acadia and Paratek Pharma. A lot of funds co-invest with Phase4 Partners, with names like Aisling Capital sharing a substantial percentage of its portfolio. Phase4 Partners has team of 1 people including 1 partners.
Key Metrics
Team Members
Portfolio Count
Portfolio Sectors
Portfolio Locations
Rounds of Entry
PE, Post IPO & 2 more
Portfolio Acquisitions

Phase4 Partners' List of Top Investments

Phase4 Partners has a portfolio of 27 companies. Their most notable investmentis in Catalyst BiosciencesTheir portfolio spans across United States, United Kingdom, Austria and 5 more locations. They have invested in Life Sciences, High Tech, Enterprise Applications and 3 other sectors, across stages such as PE, Post IPO  and 2 more. Here is the list of top investments by Phase4 Partners:
Developer of prophylactic vaccines for infectious diseases. The company's lead candidate is VLA1553 is a live-attenuated, single dose vaccine targeting the chikungunya virus. Other products includes VLA15 for Lyme Disease, VLA84 for Clostridium difficile, and VLA1601 for zika virus

Key facts about Valneva

Developer of therapeutics for central nervous system disorders. The company develop therapies for hallucinations and delusions associated with Parkinson’s disease psychosis and for the treatment of Rett syndrome

Key facts about Acadia

  • Founded Year: 1993
  • Location: San Diego (United States)
  • Annual Revenue: $1B+ as on Dec 31, 2025
  • Stage: Public
  • Total Funding till date: $44.7M
  • Employee Count: 1,000 as on May 31, 2026
  • Investors: Phase4 Partners, ACl Fund and 12 Others
  • Latest Funding Round: Post IPO, Jan 06, 2016, $*****
  • Highlight: Public
Developer of therapeutics for antimicrobial resistant infections. The company's lead candidate is NUZYRA(omadacycline), an oral and intravenous antibiotic for the treatment of adults with Community-Acquired Bacterial Pneumonia (CABP) and Acute Bacterial Skin and Skin Structure Infection (ABSSSI) caused by select susceptible microorganisms. Other drugs include Seysara for the treatment of inflammatory lesions of non-modular moderate to severe acne vulgaris.

Key facts about Paratek Pharma

Nabriva Therapeutics is developing pleuromutilin class of antibiotics for MDR infections. Its lead product candidate is Lefamulin for treating acute bacterial skin and skin structure infections (phase II); intravenous and oral formulations for the treatment of community-acquired bacterial pneumonia (CABP) (FDA approved); for pediatric indications (phase I), STI, osteomyelitis, HABP/VABP, and prosthetic joined infections (phase I). The antibiotic binds to a specific site on the bacterial ribosome responsible for bacterial protein synthesis. It has also developed Contepo (IV) for treating cUTI (NDA/MAA filing) and pediatric indications (phase I).

Key facts about Nabriva

  • Founded Year: 2006
  • Location: Vienna (Austria)
  • Annual Revenue: $10M - $50M as on Dec 31, 2022
  • Stage: Public
  • Total Funding till date: $193M
  • Employee Count: 51 - 200 as on Jul 01, 2024
  • Investors: HBM Healthcare Investments, Phase4 Partners and 18 Others
  • Latest Funding Round: Conventional Debt, Dec 21, 2018, $*****
  • Highlight: Public
Developer of novel bile acid modulators to treat gastrointestinal diseases. It offers bile acid modulators to treat orphan pediatric liver diseases and other liver and gastrointestinal disorders. Its clinical pipeline includes Elobixibat and Bylvay potent and selective ileal bile acid transporter, and A4250 a IBAT inhibitor for cholestatic liver disease.

Key facts about Albireo Pharma

  • Founded Year: 2008
  • Location: Gothenburg (Sweden)
  • Annual Revenue: $10M - $50M as on Dec 31, 2021
  • Last Known Valuation: $*****
  • Stage: Acquired
  • Total Funding till date: $40M
  • Employee Count: 3 as on Feb 28, 2021
  • Investors: Phase4 Partners, Kreos Capital and 6 Others
  • Latest Funding Round: Grant (prize money), Sep 18, 2012, $*****
  • Highlight: Acquired

Phase4 Partners' Investments by Stage

Phase4 Partners has made 1 investment in PE stage with an average round size of $50.8M, 1 investment in Post IPO stage with an average round size of $40M, 1 investment in Series A stage with an average round size of $70M and 1 investment in Series B stage with an average round size of $33M.
Here are Phase4 Partners' investments by stage:
Stage of entry
No. of Investments
PE
1
Post IPO
1
Series A
1
Series B
1
Breakdown of Phase4 Partners' investments by stage of entryPE (1)Post IPO (1)
Note: We have considered here, only first round of investments

Phase4 Partners' Investments by Sector

Phase4 Partners has a diverse portfolio, with companies operating in the Life Sciences and Sustainability Tech. Notably, it has invested in 20 Tech companies, 17 Enterprise (B2B) companies, 2 Consumer (B2C) companies and at least 2 companies focusing on Software.
Here are Phase4 Partners' investments by sector:
Sector
No. of Investments
Life Sciences
4
Sustainability Tech
2
Breakdown of Phase4 Partners' investments by sectorsLife Sciences (4)Sustainability Tech (2)
Note: We have considered here, only first round of investments

Phase4 Partners' Investments by Geography

Phase4 Partners has made most investments in United States (3), followed by Austria where it has made 1 investment.
Here are Phase4 Partners' investments by geography:
Country
No. of Investments
United States
3
Austria
1
Breakdown of Phase4 Partners' investments by countriesUnited States (3)Austria (1)
Note: We have considered here, only first round of investments

Phase4 Partners' recent investments

Phase4 Partners has not made any investment in 2026 so far.
Here are the most recent investments by Phase4 Partners:
Date
Company
Location
Round Details
Round Amount
Co-Investors
Apr 07, 2015
Austria
Series B
9479
  [+6]
Oct 28, 2009
Austria
PE
2897
Oct 25, 2007
United States
Post IPO
2146
Jan 31, 2006
Austria
PE
9825
  [+3]
Oct 25, 2005
United States
Series A
3936

IPOs and Publicly Listed companies in Phase4 Partners' Portfolio

6 of Phase4 Partners' portfolio companies have become public. Nabriva got listed on the National Association of Securities Dealers Automated Quotations (NASDAQ), in Jun 2017 at marketcap of $203M and AVANT Immunotherapeutics got listed on the National Association of Securities Dealers Automated Quotations (NASDAQ).
Here are Phase4 Partners' portfolio companies that went public:
Company
IPO Date
First Invested on
First Round of Investment
Round Size
Jun 27, 2017
Jan 31, 2006
PE
6689
Oct 01, 2008
-
-
8858
Nov 07, 2007
-
-
8328
Jun 01, 2007
-
-
8384
Apr 13, 2006
Dec 10, 2004
Series B
9902

Acquired companies in Phase4 Partners' Portfolio

12 companies from Phase4 Partners' portfolio have been acquired. The most recent acquisition was Paratek Pharma in Jun 2023 by Gurnet Point Capital for $*****.
Here are Phase4 Partners' portfolio companies that got acquired most recently:
Company
Acquisition Date
First Invested on
First Round of Investment
Round Size
Jun 06, 2023
Oct 25, 2007
Post IPO
3288
Jan 09, 2023
-
-
1571
Dec 05, 2018
-
-
1926
Apr 13, 2018
-
-
4047
Jul 27, 2016
-
-
5796

Team profile of Phase4 Partners

Phase4 Partners has a team of 1 member located in United Kingdom. Phase4 Partners' team does not sit on the board of any company as of now.

Co-investors of Phase4 Partners

Over the past 22 years, 48 investors have co-invested in Phase4 Partners's portfolio companies. This includes only funds.

  • Invested before Phase4 PartnersAuriga Partners, Nomura and 13 others have invested in rounds before Phase4 Partners. There is 1 company where Auriga Partners has invested before Phase4 Partners and 1 company where Nomura has invested before Phase4 Partners.
  • Top Co-investors of Phase4 Partners14 investors entered a company along with Phase4 Partners. These include investors like Aisling Capital (1 company).
  • Invested after Phase4 PartnersA total of 19 investors have invested in Phase4 Partners's portfolio after their investments. Top Investors include Abingworth (1 company), The Baupost Group (1 company) and HBM Healthcare Investments (1 company).

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