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About Roche

Roche is a venture capital firm founded in 1896. It is primarily based out of Basel, Switzerland. As of Nov 2021, Roche has invested in 74 companies. It primarily invests in Series B round in United States based startups. Its investments are spread across a wide range of sectors from Life Sciences to High Tech and HealthTech. Most recently it participated in the $***** Series A round of GlycoEra Overall, Roche portfolio has seen 1 unicorn, 21 IPOs and 34 acquisitions including key companies like Flatiron Health, Horizon Discovery and Ideaya Biosciences. A lot of funds co-invest with Roche, with names like SR One sharing a substantial percentage of its portfolio. Roche has team of 3 people including 1 partners.
Key Metrics
Portfolio Sectors
Portfolio Locations
Rounds of Entry
Series A, Series B & 4 more
Portfolio Unicorns
Portfolio Soonicorns

Roche's List of Top Investments

Roche has a portfolio of 74 companies, one of which is a Unicorn. Their most notable investments are in MacuLogix and Mission Therapeutics.Their portfolio spans across United States, Canada, Italy and 10 more locations. They have invested in Life Sciences, High Tech, HealthTech and 3 other sectors, across stages such as Series A, Series B  and 4 more. Here is the list of top investments by Roche:
Cloud-based practice management tool for providers. The company's OncologyCloud platform includes the electronic medical record for oncology, an analytics section for business clinical intelligence, a patient portal, and integrated billing management which allows cancer care providers and life sciences companies to track metrics related to cancer care, match patients to clinical trials and automate data collection.

Key facts about Flatiron Health

Developer of cell lines with genetic modification using AAV gene-editing platform. The company has cell line engineering, knockout cell lines, and reporter cell lines. It also provides services in T cell activation assay, lymphocyte reaction assay, T cell-mediated tumor cell lysis assay, ADCC, and CDC assays, gene-editing for immuno-oncology, CRISPR Screening, drug combination screening, in vitro assay, and in-vivo assay.

Key facts about Horizon Discovery

Developer of oncology-focused precision medicine using molecular diagnostics. The lead candidate IDE196 is a protein kinase C an inhibitor for genetically defined cancers having GNAQ or GNA11 gene mutations. Others include PARG, WRN, poltheta, Darovasertib, and others.

Key facts about Ideaya Biosciences

  • Founded Year: 2015
  • Location: San Francisco (United States)
  • Annual Revenue: $100M - $500M as on Dec 31, 2025
  • Stage: Public
  • Total Funding till date: $157M
  • Employee Count: 261 as on May 31, 2026
  • Investors: BVF Partners, Boxer Capital and 15 Others
  • Latest Funding Round: Post IPO, Aug 04, 2020, $*****
  • Highlight: Public
Developer of selective kinase inhibitors for patients with genomically defined cancers. Their approach is rooted in a deep understanding of the genetic blueprint of cancer and other diseases driven by the abnormal activation of kinases. Their ability to identify novel drivers of disease, coupled with our proprietary library of novel and diverse chemical compounds, uniquely enables us to craft kinase therapies against new and difficult-to-drug targets.

Key facts about Blueprint Medicines

  • Founded Year: 2008
  • Location: Cambridge (United States)
  • Annual Revenue: $500M - $1B as on Dec 31, 2024
  • Last Known Valuation: $*****
  • Stage: Acquired
  • Total Funding till date: $115M
  • Employee Count: 728 as on May 31, 2026
  • Investors: Foresite Capital, BVF Partners and 20 Others
  • Latest Funding Round: Post IPO, Jun 30, 2022, $*****
  • Highlight: Acquired
Developer of small molecule drugs for treating cancer. Its Degronimid platform incorporates highly selective small-molecule binders to target disease-causing proteins and facilitate their rapid destruction and clearance from the cell through the natural proteasome system. It has developed CFT7455 for treating hematologic malignancies, CFT8634 for sarcoma, BRAF V600E for slid tumors.

Key facts about C4 Therapeutics

  • Founded Year: 2016
  • Location: Cambridge (United States)
  • Annual Revenue: $10M - $50M as on Dec 31, 2025
  • Stage: Public
  • Total Funding till date: $223M
  • Employee Count: 111 as on May 31, 2026
  • Investors: HTIF, HBM Healthcare Investments and 27 Others
  • Latest Funding Round: Post IPO, Jan 04, 2024, $*****
  • Highlight: Public

Roche's Investments by Stage

Roche has made 18 investments in Series A stage with an average round size of $37.6M, 18 investments in Series B stage with an average round size of $32.7M and 5 investments in Series C stage with an average round size of $119M.
Here are Roche's investments by stage:
Stage of entry
No. of Investments
Series A
18
Series B
18
Series C
5
Series D
3
Post IPO
2
Others
1
Breakdown of Roche's investments by stage of entrySeries A (18)Series B (18)
Note: We have considered here, only first round of investments

Roche's Investments by Sector

Roche has a diverse portfolio, with companies operating in the Life Sciences, High Tech, HealthTech, Enterprise Applications and Sustainability Tech. Notably, it has invested in 66 Tech companies, 65 Enterprise (B2B) companies, 11 Software companies and at least 6 companies focusing on Consumer (B2C).
Here are Roche's investments by sector:
Sector
No. of Investments
Life Sciences
42
High Tech
14
HealthTech
7
Enterprise Applications
5
Sustainability Tech
5
Others
6
Breakdown of Roche's investments by sectorsLife Sciences (42)High Tech (14)
Note: We have considered here, only first round of investments

Roche's Investments by Geography

Roche has made most investments in United States (38), followed by United Kingdom where it has made 2 investments.
Here are Roche's investments by geography:
Country
No. of Investments
United States
38
United Kingdom
2
Austria
1
Denmark
1
France
1
Others
4
Breakdown of Roche's investments by countriesUnited States (38)United Kingdom (2)
Note: We have considered here, only first round of investments

Roche's recent investments

Roche has not made any investment in 2026 so far.
Here are the most recent investments by Roche:
Date
Company
Location
Round Details
Round Amount
Co-Investors
Nov 05, 2021
Switzerland
Series A
3552
Jan 28, 2021
Italy
Series A
3401
Aug 26, 2020
United States
Series C
5815
  [+20]
Apr 03, 2020
United States
Series D
6177
Jan 10, 2020
United States
Series B
1037
  [+6]

Unicorns in Roche's Portfolio

Roche has 1 unicorn in its portfolio - Freenome Health. The most recent unicorn in their portfolio is Freenome Health which became a unicorn in 2022, 1 years after Roche first invested in it.
Here is a list of unicorns in Roche's portfolio:
Tracxn Score
Company
Short Description
Founded year
Sector
Location
Company Stage
First Investment/ Acquisition Details
66
Provider of a deep learning platform for detecting circulating cancer-related markers
2014
-
Series E
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IPOs and Publicly Listed companies in Roche's Portfolio

21 of Roche's portfolio companies have become public. Entrada Therapeutics got listed on the National Association of Securities Dealers Automated Quotations (NASDAQ), in Oct 2021 at marketcap of $598M and TEMPEST THERAPEUTICS got listed on the National Association of Securities Dealers Automated Quotations (NASDAQ).
Here are Roche's portfolio companies that went public:
Company
IPO Date
First Invested on
First Round of Investment
Round Size
Oct 29, 2021
Dec 22, 2018
Series A
5945
Jun 16, 2021
-
-
2965
Oct 16, 2020
2018
Series A
6843
Oct 02, 2020
Jan 07, 2016
Series A
3284
Jun 12, 2020
Jul 23, 2015
Series A
8532

Acquired companies in Roche's Portfolio

34 companies from Roche's portfolio have been acquired. The most recent acquisition was Complete Genomics in Feb 2026 by Swiss Rockets for $*****.
Here are Roche's portfolio companies that got acquired most recently:
Company
Acquisition Date
First Invested on
First Round of Investment
Round Size
Feb 23, 2026
-
-
5981
Jun 02, 2025
-
-
7413
Apr 16, 2025
Jun 08, 2016
Series B
5616
Jan 13, 2025
Nov 14, 2017
Series D
9814
Jan 08, 2024
Jul 05, 2006
Series C
6806

Team profile of Roche

Roche has a team of 3 members including 1 Partner and 2 Principals located in Switzerland. Roche's team does not sit on the board of any company as of now.
Here is a list of all team members in Roche:
Name
Designation
Location
Board Memberships
Contact Details
Partner
-
-
-
Principal
Basel
-
-
Principal
Basel
-

Co-investors of Roche

Over the past 22 years, 380 investors have co-invested in Roche's portfolio companies. This includes funds and angels.

  • Invested before RocheHHS, Google Ventures and 116 others have invested in rounds before Roche. There are 6 companies where HHS has invested before Roche and 3 companies where Google Ventures has invested before Roche.
  • Top Co-investors of Roche121 investors entered a company along with Roche. These include investors like SR One (6 companies).
  • Invested after RocheA total of 141 investors have invested in Roche's portfolio after their investments. Top Investors include Roche (7 companies), Adage Capital Management (4 companies) and RA Capital Management (4 companies).

Recent News related to Roche

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