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About Room40

Room40 is a venture capital firm founded in 2017. It is primarily based out of New York City, United States. As of Nov 2025, Room40 is an active investor, having invested in 23 companies, with 1 new investment in the last 12 months. It primarily invests in Series A round in United States based startups. Its investments are spread across a wide range of sectors from Enterprise Applications to FinTech and Blockchain Technology. Most recently it participated in the $***** Series B round of Daylight Made with love Overall, Room40 portfolio has seen 4 acquisitions, namely Arbelos Markets, Waybridge and Triangle. A lot of funds co-invest with Room40, with names like Third Prime sharing a substantial percentage of its portfolio. Room40 has team of 5 people including 2 partners.
Key Metrics
Portfolio Locations
Rounds of Entry
Seed, Series A & 1 more
Portfolio Acquisitions
Portfolio Soonicorns
Deals in last 12 months

Room40's List of Top Investments

Room40 has a portfolio of 23 companies. Their most notable investments are in Mealco and MainVest.Their portfolio spans across United States, Australia, Brazil and 4 more locations. They have invested in Enterprise Applications, FinTech, Blockchain Technology and 13 other sectors, across stages such as Seed, Series A  and 1 more. Here is the list of top investments by Room40:
Accessible virtual care for women's sexual and reproductive health. They provide convenient and affordable access to essential healthcare services, including birth control, emergency contraception, abortion support, UTI and STI treatments, and more. The platform offers virtual consultations with licensed healthcare providers, prescription delivery, and a range of over-the-counter products. They focus on inclusive care for medically underserved groups, offering no-cost care options for eligible individuals. The company operates on a subscription-based model, providing standard and basic care plans with varying levels of access to products, services, and support. They also partner with various health plans to expand access to their services. They are committed to empowering individuals with trusted information and convenient access to reproductive and sexual health resources. This is a B2C healthcare platform leveraging telehealth to provide accessible and affordable women's health services.

Key facts about Twentyeight Health

Provider of a SaaS-based collaborative performance management platform. Its features include the reconciliation of data discrepancies, contextualization of service failures, actionable insights, and cost analysis for each order, shipment, and carrier.

Key facts about Isometric Technologies

Provider of residential solar power systems and battery backup units. This business facilitates the installation and maintenance of solar panels and energy storage equipment for private residences. The model enables homeowners to generate and store electrical power, functioning as a decentralized energy resource. Installations include design, permitting, and hardware implementation. The service provides ongoing energy management through software applications to monitor power generation, usage, and storage levels. Participation in this program allows for the utilization of renewable energy while maintaining power availability during outages.

Key facts about Daylight Made with love

Online marketplace for crypto loans. It enables institutions to borrow from liquidity pools funded by the DeFi ecosystem. Liquidity providers can earn yield from pools of borrowers managed by pool delegates.

Key facts about Maple

Developer of a protocol for agent to agent advertising infrastructure. This platform facilitates communication between automated buyer and seller agents to manage advertising campaigns. It enables organizations to coordinate investment across multiple media channels while maintaining brand standards and strategic objectives through an open architectural framework. The system integrates with various large language models and software interfaces to automate media planning, negotiation, and delivery reporting. By providing a unified connection point, the architecture allows for scalable cross-channel campaign execution and data-driven budget allocation without requiring manual intervention for individual ad placements.

Key facts about Scope3

Room40's Investments by Stage

Room40 has made 6 investments in Seed stage with an average round size of $9.2M, 5 investments in Series A stage with an average round size of $12.4M and 3 investments in Series B stage with an average round size of $21.7M.
Here are Room40's investments by stage:
Stage of entry
No. of Investments
Seed
6
Series A
5
Series B
3
Breakdown of Room40's investments by stage of entrySeed (6)Series A (5)
Note: We have considered here, only first round of investments

Room40's Investments by Sector

Room40 has a diverse portfolio, with companies operating in the Enterprise Applications, FinTech, Vertical SaaS, Blockchain Technology and HealthTech. Notably, it has invested in 20 Tech companies, 14 Enterprise (B2B) companies, 11 Software companies and at least 7 companies focusing on Consumer (B2C).
Here are Room40's investments by sector:
Sector
No. of Investments
Enterprise Applications
7
FinTech
7
Vertical SaaS
3
Blockchain Technology
2
HealthTech
2
Others
13
Breakdown of Room40's investments by sectorsEnterprise Applic... (7)FinTech (7)
Note: We have considered here, only first round of investments

Room40's Investments by Geography

Room40 has made most investments in United States (11), followed by China where it has made 1 investment.
Here are Room40's investments by geography:
Country
No. of Investments
United States
11
China
1
Israel
1
Breakdown of Room40's investments by countriesUnited States (11)China (1)
Note: We have considered here, only first round of investments

Room40's recent investments

Room40 has not made any investment in 2026 so far.
Here are the most recent investments by Room40:
Date
Company
Location
Round Details
Round Amount
Co-Investors
Nov 02, 2025
-
Series B
4010
Oct 13, 2024
United States
Series C
8044
Jul 30, 2024
Israel
Seed
4961
May 08, 2024
United States
Seed
9372
  [+10]
May 08, 2024
United States
Conventional Debt
2329
  [+10]

Acquired companies in Room40's Portfolio

4 companies from Room40's portfolio have been acquired. The most recent acquisition was Arbelos Markets in Jan 2025 by FalconX for $*****.
Here are Room40's portfolio companies that got acquired most recently:
Company
Acquisition Date
First Invested on
First Round of Investment
Round Size
Jan 02, 2025
May 08, 2024
Seed
5093
Nov 01, 2024
-
-
6906
May 22, 2023
Sep 28, 2021
Series A
9852
Mar 02, 2023
May 14, 2021
Series B
3006

Team profile of Room40

Room40 has a team of 5 members including 2 Partners located in United States. Room40's team does not sit on the board of any company as of now.

Co-investors of Room40

Over the past 7 years, 125 investors have co-invested in Room40's portfolio companies. This includes funds and angels.

  • Invested before Room40: L37, Kindred Ventures and 23 others have invested in rounds before Room40. There is 1 company where L37 has invested before Room40 and 1 company where Kindred Ventures has invested before Room40.
  • Top Co-investors of Room40: 83 investors entered a company along with Room40. These include investors like Third Prime (2 companies).
  • Invested after Room40: A total of 17 investors have invested in Room40's portfolio after their investments. Top Investors include Seae Ventures (1 company), Impact America Fund (1 company) and Maycomb Capital (1 company).

Recent News related to Room40

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FAQs about Room40

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