About Seed-One Ventures
Seed-One Ventures is a venture capital firm founded in 1997. It is primarily based out of Miami, United States. It primarily invests in United States based startups. Its investments are spread across a wide range of sectors from Life Sciences to Enterprise Applications and FinTech. Overall, Seed-One Ventures portfolio has seen 1 IPO and 3 acquisitions, namely TyRx, Zeltiq and NightHawk Biosciences. Seed-One Ventures has team of 2 people including 1 partners.Key Metrics
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Portfolio Locations
Portfolio IPOs
Portfolio Soonicorns
Seed-One Ventures' List of Top Investments
Seed-One Ventures has a portfolio of 9 companies. Their most notable investments include Cardiac Dimensions and EndoGastric Solutions.Their portfolio spans across United States and France. They have invested in Life Sciences, Enterprise Applications, FinTech and 6 other sectors. Here is the list of top investments by Seed-One Ventures:Cardiac Dimensions is a developer of invasive cardiac implants for heart failure. The medical device company focused on treatment of heart failure and mitral regurgitation (MR). The Carillon Mitral Contour System is a non-surgical device to treat functional MR. This permanent implant is placed using a catheter-based procedure via the jugular vein to reshape the mitral valve.
Key facts about Cardiac Dimensions
- Founded Year: 2001
- Location: Kirkland (United States)
- Stage: Series E
- Total Funding till date: $261M
- Employee Count: 73 as on Mar 31, 2026
- Investors: Life Sciences Partners, Horizon 3 Healthcare and 20 Others
- Latest Funding Round: Series E, Mar 20, 2025, $*****
- Highlight: Editors' Pick
Endoluminal solutions for digestive diseases, restoring anatomy and improving patient outcomes. They specialize in minimally invasive therapies for gastroesophageal reflux disease (GERD), offering innovative medical devices and procedures designed to restore the natural state of the anatomy. Their flagship technology provides a lower side-effect profile compared to alternative options, improving the quality of life for patients. They are committed to training and education for healthcare providers, ensuring proper technique and optimal patient results. They focus on community outreach and adhere to regulatory labeling standards, prioritizing patient safety and ethical practices. They offer a comprehensive approach to GERD treatment, providing support and resources for both patients and providers.
Key facts about EndoGastric Solutions
- Founded Year: 2002
- Location: San Mateo (United States)
- Stage: Series J
- Total Funding till date: $355M
- Employee Count: 17 as on Mar 31, 2026
- Investors: Accelmed, CRG and 14 Others
- Latest Funding Round: Series J, Dec 03, 2021, $*****
- Highlight: Editors' Pick
3. TyRx
TYRX Antibacterial Envelopes help stabilize Cardiac Implantable Devices (CIEDs) while also helping to reduce Surgical Site Infections (SSIs) such as Pacemaker Pocket Infection. The company was acquired by Medtronic in 2014.
Key facts about TyRx
- Founded Year: 1998
- Location: Monmouth Junction (United States)
- Stage: Acquired
- Total Funding till date: $70.8M
- Employee Count: 42 as on Dec 31, 2022
- Investors: Comerica, MemorialCare Innovation Fund and 6 Others
- Latest Funding Round: Series C, May 15, 2013, $*****
- Highlight: Acquired
4. Zeltiq
Permanently eliminate treated fat with CoolSculpting, a non-surgical body contouring solution. It offers a way to reduce fat in areas like the stomach, love handles, thighs, and upper arms. The treatment works by freezing fat cells, which are then naturally eliminated from the body. It is a non-surgical alternative for individuals seeking to refine their body shape. It provides personalized treatment plans through consultations with healthcare providers. It offers a non-invasive approach to body contouring, allowing individuals to achieve a more sculpted physique without surgery or extensive downtime. It also offers loyalty programs and financing options to make treatments more accessible. It is backed by clinical research and has performed treatments worldwide. Keywords: body contouring, fat reduction, non-surgical, cryolipolysis, treatment areas, consultation, healthcare providers, personalized plans, loyalty program, financing, aesthetics, cosmetic procedure.
Key facts about Zeltiq
- Founded Year: 2005
- Location: Pleasanton (United States)
- Stage: Acquired
- Total Funding till date: $70.4M
- Employee Count: 92 as on Jan 31, 2026
- Investors: Aisling Capital, Venrock and 4 Others
- Latest Funding Round: Series D, Jun 03, 2010, $*****
- Highlight: Acquired
Key facts about NightHawk Biosciences
- Founded Year: 2008
- Location: Morrisville (United States)
- Annual Revenue: $1M - $10M as on Dec 31, 2024
- Stage: Public
- Total Funding till date: $8.13M
- Investors: Hunter Trust, Seed-One Ventures and 1 Other
- Latest Funding Round: Grant (prize money), Sep 19, 2023, $*****
- Highlight: Public
IPOs and Publicly Listed companies in Seed-One Ventures' Portfolio
1 of Seed-One Ventures' portfolio company became public - NightHawk Biosciences. It got listed on the National Association of Securities Dealers Automated Quotations (NASDAQ), in Jul 2013 at marketcap of $60.9MHere are Seed-One Ventures' portfolio companies that went public:
Company | IPO Date | First Invested on | First Round of Investment | Round Size |
|---|---|---|---|---|
Jul 26, 2013 | - | - | 4114 |
Acquired companies in Seed-One Ventures' Portfolio
3 companies from Seed-One Ventures' portfolio have been acquired. The most recent acquisition was Zeltiq in Feb 2017 by Allergan for $*****.Here are Seed-One Ventures' portfolio companies that got acquired most recently:
Company | Acquisition Date | First Invested on | First Round of Investment | Round Size |
|---|---|---|---|---|
Feb 13, 2017 | - | - | 3375 | |
Jan 06, 2014 | - | - | 2755 | |
Oct 15, 2009 | - | - | 4548 |
Team profile of Seed-One Ventures
Seed-One Ventures has a team of 2 members including 1 Partner and 1 Principal located in United States. Seed-One Ventures' team does not sit on the board of any company as of now.Recent News related to Seed-One Ventures
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The GreenGo Consignment, now Bibak, raises €6 millionNotus Technologies•Feb 13, 2023•Notus Technologies, SWEN Capital Partners, Founders Future, Seed-One Ventures and 2 others

