About Sprig Equity
Sprig Equity is a venture capital firm founded in 2022. It is primarily based out of Wilmette, United States. As of Mar 2025, Sprig Equity has invested in 19 companies. It primarily invests in Series D round in United States based startups. Its investments are spread across a wide range of sectors from Life Sciences to HealthTech and High Tech. Most recently it participated in the $***** Series F round of SetPoint Medical Overall, Sprig Equity portfolio has seen 1 IPO and 13 acquisitions including key companies like NeuroPace, Valeritas and Vertos Medical. A lot of funds co-invest with Sprig Equity, with names like Elevage Medical Technologies sharing a substantial percentage of its portfolio. Sprig Equity has team of 17 people including 2 partners.Key Metrics
Team Members
Portfolio Count
Portfolio Sectors
Portfolio Locations
Rounds of Entry
Series D & Series F
Portfolio IPOs
Portfolio Acquisitions
Portfolio Soonicorns
Sprig Equity's List of Top Investments
Sprig Equity has a portfolio of 19 companies. Their most notable investmentis in Conformal MedicalTheir portfolio spans across United States, Israel and Switzerland. They have invested in Life Sciences, HealthTech, High Tech and 1 other sectors, across stages such as Series D, Series F stages. Here is the list of top investments by Sprig Equity:1. NeuroPace
Developer of implantable neurostimulation system for epilepsy treatment. The system delivers personalized treatment by responding to abnormal brain activity and provides EEG data to improve patient care. It offers a potential solution for adults with drug-resistant focal epilepsy, aiming to reduce seizures and manage quality of life. The device is intended for patients with localized seizure foci and requires prior diagnostic testing. The company also provides resources and support for patients and healthcare providers.
Key facts about NeuroPace
- Founded Year: 1997
- Location: Mountain View (United States)
- Annual Revenue: $79.9M as on Dec 31, 2024
- Stage: Public
- Total Funding till date: $264M
- Employee Count: 242 as on Mar 31, 2026
- Investors: Accelmed, Domain Associates and 15 Others
- Latest Funding Round: Series E, Aug 19, 2020, $*****
- Highlight: Public
Developer of implantable neuromodulation devices for inflammatory diseases. It offers the SetPoint System which is a a small, wireless, implantable device that stimulates the vagus nerve activating the body’s innate pathways to reduce inflammation and restore immunologic balance.
Key facts about SetPoint Medical
- Founded Year: 2006
- Location: Santa Clarita (United States)
- Stage: Series F
- Total Funding till date: $388M
- Employee Count: 93 as on Mar 31, 2026
- Investors: Topspin Fund, Viking Global Investors and 32 Others
- Latest Funding Round: Series F, Mar 27, 2025, $*****
- Highlight: Editors' Pick
3. CytoVale
CytoVale is focussed on developing biomarkers for the early detection of sepsis, an infectious reaction that can lead to lung, kidney and liver failure. Its technology is based on the mechanical properties of individual cells (mechanomics). The instrument uses microfluidics to route and physically probe individual cells and claims to have the capacity to measure over 10 biophysical cell markers at rates above 2k cells per second, providing a high-throughput detection of the disease.
Key facts about CytoVale
- Founded Year: 2013
- Location: San Francisco (United States)
- Stage: Series D
- Total Funding till date: $207M
- Employee Count: 121 as on Feb 28, 2026
- Investors: Medical Countermeasures, Sands Capital and 18 Others
- Latest Funding Round: Series D, Oct 11, 2024, $*****
- Highlight: Editors' Pick
Innovating stroke prevention with minimally invasive Left Atrial Appendage Occlusion. This company focuses on addressing the clinical need for improved stroke prevention in patients with Atrial Fibrillation (Afib). The company is developing a system for Left Atrial Appendage Occlusion (LAAO) as an alternative to blood thinners, aiming to reduce stroke risk without increased bleeding risk. Their solution targets a single-operator, same-day procedure performed under conscious sedation, eliminating the need for transesophageal echocardiography (TEE). This medical device company is dedicated to transforming LAAO procedures, offering a minimally invasive solution for stroke prevention. They are committed to advancing patient care through innovative medical technology.
Key facts about Conformal Medical
- Founded Year: 2016
- Location: Nashua (United States)
- Stage: Series D
- Total Funding till date: $161M
- Employee Count: 57 as on Mar 31, 2026
- Investors: Fidelity Investments, Catalyst Health Ventures and 4 Others
- Latest Funding Round: Series D, Jul 31, 2025, $*****
- Highlight: Editors' Pick
5. Valeritas
Developer of wearable insulin patch pumps for insulin delivery through the skin. It offers holds one day's supply of fast-acting insulin and releases it at a continuous preset basal rate and on-demand bolus dosing at mealtimes. Its pump is not programmable and does not use electricity. Its devices are available at a preset basal rate to deliver diverse amounts of insulin in a day and on-demand bolus dosing.
Key facts about Valeritas
- Founded Year: 2003
- Location: Bridgewater (United States)
- Stage: Acquired
- Total Funding till date: $231M
- Employee Count: 141 as on Dec 31, 2019
- Investors: Kaiser Permanente Ventures, Montrose Capital Partners and 12 Others
- Latest Funding Round: Post IPO, May 04, 2016, $*****
- Highlight: Acquired
Sprig Equity's Year-on-Year Investment Trends
Sprig Equity has invested in 19 companies over the last 3 years, with an average of 1 new investment annually in the last 3 years. In 2025, it made 1 investment. Its most recent first time investment was in SetPoint Medical.Sprig Equity's Investments by Stage
Sprig Equity has made 1 investment in Series D stage with an average round size of $35M and 1 investment in Series F stage with an average round size of $140M.Sprig Equity's Investments by Sector
Sprig Equity has a portfolio focused on Life Sciences. Notably, it has invested in 17 Enterprise (B2B) companies, 17 Tech companies, 9 Tech hardware companies and at least 5 companies focusing on Software.Sprig Equity's Investments by Geography
Sprig Equity has made most investments in United States (2).Sprig Equity's recent investments
Sprig Equity has not made any investment in 2026 so far.Here are the most recent investments by Sprig Equity:
Filter this listDate | Company | Location | Round Details | Round Amount | Co-Investors |
|---|---|---|---|---|---|
Mar 27, 2025 | United States | Series F | 6087 | ||
May 26, 2023 | United States | Series D | 1566 | - |
IPOs and Publicly Listed companies in Sprig Equity's Portfolio
1 of Sprig Equity's portfolio company became public - NeuroPace. It got listed on the National Association of Securities Dealers Automated Quotations (NASDAQ), in Apr 2021 at marketcap of $390MHere are Sprig Equity's portfolio companies that went public:
Company | IPO Date | First Invested on | First Round of Investment | Round Size |
|---|---|---|---|---|
Apr 22, 2021 | - | - | 6851 |
Acquired companies in Sprig Equity's Portfolio
13 companies from Sprig Equity's portfolio have been acquired. The most recent acquisition were Vertos Medical in Aug 2024 by Stryker.Here are Sprig Equity's portfolio companies that got acquired most recently:
Company | Acquisition Date | First Invested on | First Round of Investment | Round Size |
|---|---|---|---|---|
Aug 22, 2024 | - | - | 4221 | |
Jan 10, 2022 | - | - | 8538 | |
Apr 12, 2021 | - | - | 4889 | |
Feb 10, 2020 | - | - | 1334 | |
Jul 09, 2018 | - | - | 3227 |
Team profile of Sprig Equity
Sprig Equity has a team of 17 members including 2 Partners and 3 Venture Partners located in United States. Sprig Equity's team does not sit on the board of any company as of now.Here is a list of top team members in Sprig Equity:
Name | Designation | Location | Board Memberships | Contact Details |
|---|---|---|---|---|
Partner | Wilmette | - | ||
Partner | Orange | - | ||
Venture Partner | - | - | - | |
Venture Partner | Chicago | - | - | |
Venture Partner | - | - | - |
Co-investors of Sprig Equity
Over the past 3 years, 33 investors have co-invested in Sprig Equity's portfolio companies. This includes funds and angels.
- Invested before Sprig Equity: Runway Growth Capital, New Enterprise Associates and 27 others have invested in rounds before Sprig Equity. There is 1 company where Runway Growth Capital has invested before Sprig Equity and 1 company where New Enterprise Associates has invested before Sprig Equity.
- Top Co-investors of Sprig Equity: 4 investors entered a company along with Sprig Equity. These include investors like Elevage Medical Technologies (1 company).
Recent News related to Sprig Equity
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SetPoint Medical Raises $140M to Commercialize Rheumatoid Arthritis TherapyHIT Consultant•Aug 12, 2025•SetPoint Medical, Ally Bridge Group, Elevage Medical Technologies, Norwest Venture Partners and 3 others
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Conformal Medical raises $35M in oversubscribed Series DMassDevice•Jun 05, 2023•Conformal Medical, Sprig Equity
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Conformal Medical Raises $35 Million in Oversubscribed Series D RoundMedical Device News•Jun 05, 2023•Conformal Medical, Sprig Equity
