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Fractyl - About the company

Fractyl is a public company based in Lexington (United States), founded in 2010 by Harith Rajagopalan. It operates as a Provider of Endoscopic procedure for type - 2 diabetes. Fractyl has raised $345M in funding from investors like Deerfield Triarc Capital, Mithril and Maverick Ventures. The company has 57 active competitors, including 24 funded and 13 that have exited. Its top competitors include companies like Adocia, MeiraGTx and D&D Pharmatech.

Company Details

Provider of Endoscopic procedure for type - 2 diabetes. Fractyl is developing an investigational, device-based, minimally invasive, trans-oral procedure known as Revita duodenal mucosal resurfacing (DMR) that aims to improve the body's response to sugar. Performed using Fractyl’s proprietary Revita System, the DMR procedure uses hydrothermal ablation to modify the lining of the duodenum. Fractyl’s proprietary Revita™ System consists of a console and a novel single-use balloon catheter. The physician first introduces the Revita™ catheter through the mouth into the small intestine using a standard endoscope to visualize the catheter position. The physician then uses the Revita™ System to activate a precisely controlled heated balloon at the end of the catheter to treat the lining of the duodenum. The lining of the duodenum contains cells that affect glucose control and insulin resistance.
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Email ID
*****@fractyl.com
Key Metrics
Founded Year
2010
Location
Lexington, United States
Stage
Public
Total Funding
$345M in 7 rounds
Latest Funding Round
Ranked
Annual Revenue
$0 - $1M as on Dec 31, 2024
Employee Count
105 as on Sep 30, 2026
Similar Companies
Exit Details
Public

Fractyl's IPO details

Fractyl got listed on Feb 02, 2024.
Click here to take a look at Fractyl's IPO in detail
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Fractyl's funding and investors

Fractyl has raised a total funding of $345M over 7 rounds. Its first funding round was on Mar 21, 2013. Its latest funding round was a Series F round on Jun 16, 2021 for $*****. 3 investors participated in its latest round. Fractyl has 19 institutional investors.

Here is the list of recent funding rounds of Fractyl:lockFilter this list
Date of Funding
Funding Amount
Round Name
Post-Money Valuation
Revenue Multiple
Lead Investors
Other Investors
Jun 16, 2021
7741381
Series F
6993672
1300430
6262757
8836270
Aug 06, 2020
7348722
Series E
3935330
8124352
3653520
Mar 19, 2020
5157396
Series D
1675445
5000177
5031568
8746545
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Fractyl's founders and board of directors

Founder? Claim Profile
The founders of Fractyl is Harith Rajagopalan.
Here are the details of Fractyl's key team members:

Fractyl's employee count trend

Fractyl has 105 employees as of Sep 26. Here is Fractyl's employee count trend over the years:
Employee count trend for Fractyl
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Fractyl's Competitors and alternates

Top competitors of Fractyl include Adocia, MeiraGTx and D&D Pharmatech. Here is the list of Top 10 competitors of Fractyl, ranked by Tracxn score:
Rank
Company Details
Short Description
Total Funding
Investors
Tracxn Score
1st
Logo for Adocia
Adocia
2005, Lyon (France), Public
Developer of therapeutics for the treatment of diabetes and obesity
$26M
69/100
2nd
Logo for MeiraGTx
MeiraGTx
2015, New York City (United States), Public
Developer of gene therapies for ocular and neurodegenerative diseases
-
65/100
3rd
Logo for D&D Pharmatech
D&D Pharmatech
2014, Seongnam-si (South Korea), Public
Developer of GLP-1-based therapeutics for metabolic disease treatment
$205M
64/100
4th
Logo for Enveda
Enveda
2019, Boulder (United States), Series D
AI-based platform to decipher the chemistry of nature and develop new medicines
$517M
63/100
5th
Logo for MBX Biosciences
MBX Biosciences
2018, Carmel (United States), Public
Developer of drugs for the treatment of rare endocrine diseases
$216M
61/100
6th
Logo for Metsera
Metsera
2022, New York City (United States), Acquired
Biopharmaceutical company focusing on medicines for obesity and metabolic diseases
$505M
61/100
7th
Logo for Congruence Therapeutics
Congruence Therapeutics
2021, Montreal (Canada), Series B
Developer of therapeutics for the treatment of rare diseases
$136M
61/100
8th
Logo for Skye Bioscience
Skye Bioscience
2011, San Diego (United States), Public
Developer of cannabinoid-based therapies for the treatment of glaucoma and other diseases
$1.97M
57/100
9th
Logo for Biophytis
Biophytis
2006, Romainville (France), Public
Developer of drugs for neuromuscular and age-related diseases
$2.6M
56/100
10th
Logo for Remedy Plan
Remedy Plan
2011, Washington, DC (United States), Series B
Developing first-in-class NAMPT inhibitors for oncology, autoimmune, and metabolic diseases
$24.7M
56/100
11th
Logo for Fractyl
Fractyl
2010, Lexington (United States), Public
Provider of Endoscopic procedure for type - 2 diabetes
$345M
56/100
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Fractyl's Investments and acquisitions

Fractyl has made no investments or acquisitions yet.

Reports related to Fractyl

Here is the latest report on Fractyl's sector:

News related to Fractyl

lockFilter this list
Media has covered Fractyl for a total of 11 events in the last 1 year, 7 of them have been about company updates.
•
Fractyl Health's GLP-1 Gene Therapy Trial Gets Green Light from European Authoritieshttps://www.clinicaltrialsarena.com/•May 11, 2026•Fractyl
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