About Exome Asset Management
Exome Asset Management is a family office founded in 2018. It is primarily based out of New York City, United States. As of Sep 2026, Exome Asset Management is an active investor, having invested in 7 companies, with 1 new investments in the last 12 months. It primarily invests in Post IPO round in United States based companies. Its investments are spread across a wide range of sectors from Life Sciences, High Tech. Its latest investment was a $21.5M Post IPO round in NextCure on Nov 12, 2025, which also saw participation from Ikarian Capital and squadroncap.com.
Overall, Exome Asset Management portfolio has seen 6 IPOs and 1 acquisition including key companies like NextCure, Aprea and Impact Therapeutics. A lot of funds co-invest with Exome Asset Management, with names like Ikarian Capital sharing a substantial percentage of its portfolio.
Exome Asset Management has a team of 7 people including 1 partner.
Key Metrics
Founded Year
2018
Location
New York City, United States
Sectors of Investment
Stages of Investment
Post IPO, Series D & 1 more
Locations of Investment
Exome Asset Management's List of Top Investments
Exome Asset Management has a portfolio of 7 companies. Their most notable investmentis in Zhejiang Nuhui Health TechnologyTheir portfolio spans across United States, China and Sweden. They have invested in Life Sciences, High Tech, Enterprise Applications, across Post IPO, Series D and 1 more. Here is the list of top investments by Exome Asset Management:1. NextCure
Developer of next-generation immuno-oncology-based drugs. The proprietary platforms and know-how to identify novel and biologically relevant targets and develop first-in-class immunotherapy products. The pipeline candidates include NC318 for tumor and macrophages, NC410 for myeloid and T-cells, NC762 for tumors, NC252 for leukemia cells, and others.
Key facts about NextCure
- Founded Year: 2015
- Location: New Haven (United States)
- Annual Revenue: $10M - $50M as on Dec 31, 2020
- Stage: Public
- Total Funding till date: $175M
- Employee Count: 54 as on Apr 03, 2025
- Investors: ArrowMark Partners, Timefolio Capital and 19 Others
- Latest Funding Round: Post IPO, Nov 12, 2025, $*****
- Highlight: Public

2. Aprea
Developer of small molecule therapeutics targeting tumor suppressor proteins. The company focuses on p53, a tumor suppressor protein that induces cell cycle arrest or cell death. The company's lead candidate is APR-246, that acts by reactivating mutant and defective native p53, leading to tumor cell death. The company is also developing APR-017, which induces p53-mediated apoptosis by restoring p53 activity in cancer cell lines with mutant p53.
Key facts about Aprea
- Founded Year: 2003
- Location: Boston (United States)
- Stage: Public
- Total Funding till date: $113M
- Investors: ADS Ventures, Janus Henderson Investors and 15 Others
- Latest Funding Round: Post IPO, Dec 09, 2025, $*****
- Highlight: Public
Developer of small molecule therapeutics for the treatment of cancer. The company's product line include Senaparib is a PARP inhibitor for ovarian cancer maintenance therapy and small cell lung cancer, meeting primary endpoints in the FLAMES study for superior efficacy and safety. Other assets include WEE1 inhibitor IMP7068, ATR inhibitor IMP9064, and PARP1-selective inhibitor IMP1734 (collaborating with Eikon Therapeutics), alongside additional DDR inhibitors.
Key facts about Impact Therapeutics
- Founded Year: 2009
- Location: Nanjing (China)
- Stage: Public
- Total Funding till date: $180M
- Investors: Decheng Capital, Exome Asset Management and 21 Others
- Latest Funding Round: Series D, Nov 15, 2024, $*****
- Highlight: Public
4. Broncus
Developer of solutions for diagnosing and treating lung disease. The company has developed the Archimedes navigation bronchoscopy system, which includes BTPNA (Bronchoscopic Trans-Parenchymal Nodule Access) that combines state-of-the-art nodule, vessel, and airway mapping, pathway guidance, and augmented fluoroscopic imaging enabling unprecedented biopsy and therapeutic access to any location in the lung. It also offer InterVapor Bronchoscopic Thermal Vapor Ablation is a non-surgical, non-implant therapy designed to improve lung function.
Key facts about Broncus
- Founded Year: 1998
- Location: San Jose (United States)
- Annual Revenue: $1M - $10M as on Dec 31, 2024
- Stage: Public
- Total Funding till date: $82.5M
- Employee Count: 63 as on Aug 31, 2026
- Investors: Western Technology Investment, Saints Capital and 33 Others
- Latest Funding Round: Series G, Jan 28, 2021, $*****
- Highlight: Public
Provider of early cancer screening and testing services. The company has developed a fecal gene analysis (FIT-DNA) technology for colorectal cancer screening. The company also has a product for gastric cancer detection through their Helicobacter pylori toxicity factor detection technology. The company leverages its expertise in genetic testing, molecular diagnostics, and large data platforms and software in developing early detection tests for cancer.
Key facts about Zhejiang Nuhui Health Technology
- Founded Year: 2013
- Location: Beijing (China)
- Stage: Public
- Total Funding till date: $152M
- Employee Count: 501 - 1,000 as on Jul 01, 2024
- Investors: Rock Springs Capital, Exome Asset Management and 19 Others
- Latest Funding Round: Series E, Jul 10, 2020, $*****
- Highlight: Public
Exome Asset Management's Year-on-Year Investment Trends
Exome Asset Management has invested in 7 companies over the last 6 years, with an average of 1 new investment annually in the last 5 years. In 2025, it made 1 investment. Its most recent first time investment was in NextCure.Year | No. of Investments | ||
|---|---|---|---|
1st Round | Follow-on | Total | |
2026 (YTD) | 0 | 0 | 0 |
2025 | 1 | 0 | 1 |
2024 | 1 | 0 | 1 |
2023 | 1 | 0 | 1 |
2022 | 1 | 0 | 1 |
2021 | 1 | 0 | 1 |
2020 | 2 | 0 | 2 |
Exome Asset Management's Investments by Stage
Exome Asset Management has made 4 investments in Post IPO stage with an average round size of $31M, 2 investments in Series D stage with an average round size of $20M and 1 investment in Series G stage.Stage of entry | No. of Investments |
|---|---|
Post IPO | 4 |
Series D | 2 |
Series G | 1 |
Note: We have considered here, only first round of investments
Exome Asset Management's Investments by Sector
Exome Asset Management has a diverse portfolio, with companies operating in the Life Sciences, Enterprise Applications and High Tech. Notably, it has invested in 7 Enterprise (B2B) companies, 7 Tech companies, 1 Saas company and at least 1 company focusing on Software.Sector | No. of Investments |
|---|---|
Life Sciences | 7 |
Enterprise Applications | 1 |
High Tech | 1 |
Note: We have considered here, only first round of investments
Exome Asset Management's Investments by Geography
Exome Asset Management has made most investments in United States (4), followed by China where it has made 3 investments.Country | No. of Investments |
|---|---|
United States | 4 |
China | 3 |
Sweden | 1 |
Note: We have considered here, only first round of investments
Exome Asset Management's recent investments
Exome Asset Management has not made any investment in 2026 so far.Here are the most recent investments by Exome Asset Management:
Date | Company | Location | Round Details | Round Amount | Co-Investors |
|---|---|---|---|---|---|
Nov 12, 2025 | United States | Post IPO | 1897 | [+2] | |
Mar 11, 2024 | United States | Post IPO | 7417 | ||
Aug 07, 2023 | China | Post IPO | 5298 | [+7] | |
Mar 14, 2022 | China | Series D | 8007 | [+6] | |
Jan 28, 2021 | United States | Series G | 9904 |
IPOs and Publicly Listed companies in Exome Asset Management's Portfolio
6 of Exome Asset Management's portfolio companies have become public. Impact Therapeutics got listed on the Hong Kong Exchanges (HKG), in May 2026 at marketcap of $710M and Broncus got listed on the Hong Kong Exchanges (HKG) at marketcap of $1.26B.Here are Exome Asset Management's portfolio companies that went public:
Company | IPO Date | First Invested on | First Round of Investment | Round Size |
|---|---|---|---|---|
May 13, 2026 | Mar 14, 2022 | Series D | 5265 | |
Sep 24, 2021 | Jan 28, 2021 | Series G | 9689 | |
Feb 18, 2021 | Apr 21, 2020 | Series D | 8201 | |
Oct 03, 2019 | Mar 11, 2024 | Post IPO | 7957 | |
May 09, 2019 | Nov 12, 2025 | Post IPO | 5050 |
Acquired companies in Exome Asset Management's Portfolio
1 company from Exome Asset Management's portfolio has been acquired. The most recent acquisition was Gracell Bio in Dec 2023 by AstraZeneca for $*****.Here are Exome Asset Management's portfolio companies that got acquired most recently:
Company | Acquisition Date | First Invested on | First Round of Investment | Round Size |
|---|---|---|---|---|
Dec 26, 2023 | Aug 07, 2023 | Post IPO | 2932 |
Team profile of Exome Asset Management
Exome Asset Management has a team of 7 members located in United States. Exome Asset Management's team does not sit on the board of any company as of now.Co-investors of Exome Asset Management
Over the past 6 years, 104 investors have co-invested in Exome Asset Management's portfolio companies. This includes only funds.
- Invested before Exome Asset Management: Lilly Asia Ventures, 6 Dimensions Capital and 69 others have invested in rounds before Exome Asset Management. There are 3 companies where Lilly Asia Ventures has invested before Exome Asset Management and 3 companies where 6 Dimensions Capital has invested before Exome Asset Management.
- Top Co-investors of Exome Asset Management: 24 investors entered a company along with Exome Asset Management. These include investors like Ikarian Capital (1 company).
- Invested after Exome Asset Management: A total of 9 investors have invested in Exome Asset Management's portfolio after their investments. Top Investors include ShenZhen GTJA Investment Group (1 company) and Xicheng Jinrui (1 company).
Recent News related to Exome Asset Management
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Geron Corporation $GERN Shares Acquired by Exome Asset Management LLCMarketBeat•Sep 11, 2025•Exome Asset Management, Geron
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Aprea Therapeutics announces private placement financing of up to $34MSeeking Alpha•Mar 11, 2024•Aprea, Sphera Fund, DAFNA Capital Management, Exome Asset Management and 2 others
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Impact Therapeutics Announces Completion of Series D1 FinancingPR Newswire•Mar 14, 2022•Impact Therapeutics, Dingxin Capital, CCBT, BestRide and 4 others
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China's Broncus raises $215m in IPO, struggles on HK debutAsian Venture Capital Journal•Sep 27, 2021•Broncus, Exome Asset Management
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Broncus Holding Corporation Closed Series D FinancingACN Newswire•Jan 27, 2021•Broncus, Exome Asset Management, Valiance Capital, Summer Capital and 1 other
