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About Exome Asset Management

Exome Asset Management is a family office founded in 2018. It is primarily based out of New York City, United States. As of Sep 2026, Exome Asset Management is an active investor, having invested in 7 companies, with 1 new investments in the last 12 months. It primarily invests in Post IPO round in United States based companies. Its investments are spread across a wide range of sectors from Life Sciences, High Tech. Its latest investment was a $21.5M Post IPO round in NextCure on Nov 12, 2025, which also saw participation from Ikarian Capital and squadroncap.com.
Overall, Exome Asset Management portfolio has seen 6 IPOs and 1 acquisition including key companies like NextCure, Aprea and Impact Therapeutics. A lot of funds co-invest with Exome Asset Management, with names like Ikarian Capital sharing a substantial percentage of its portfolio.
Exome Asset Management has a team of 7 people including 1 partner.
Key Metrics
Founded Year
2018
Location
New York City, United States
Portfolio Companies
Sectors of Investment
Stages of Investment
Post IPO, Series D & 1 more
Locations of Investment

Exome Asset Management's List of Top Investments

Exome Asset Management has a portfolio of 7 companies. Their most notable investmentis in Zhejiang Nuhui Health TechnologyTheir portfolio spans across United States, China and Sweden. They have invested in Life Sciences, High Tech, Enterprise Applications, across Post IPO, Series D  and 1 more. Here is the list of top investments by Exome Asset Management:
Developer of next-generation immuno-oncology-based drugs. The proprietary platforms and know-how to identify novel and biologically relevant targets and develop first-in-class immunotherapy products. The pipeline candidates include NC318 for tumor and macrophages, NC410 for myeloid and T-cells, NC762 for tumors, NC252 for leukemia cells, and others.

Key facts about NextCure

Developer of small molecule therapeutics targeting tumor suppressor proteins. The company focuses on p53, a tumor suppressor protein that induces cell cycle arrest or cell death. The company's lead candidate is APR-246, that acts by reactivating mutant and defective native p53, leading to tumor cell death. The company is also developing APR-017, which induces p53-mediated apoptosis by restoring p53 activity in cancer cell lines with mutant p53.

Key facts about Aprea

Developer of small molecule therapeutics for the treatment of cancer. The company's product line include Senaparib is a PARP inhibitor for ovarian cancer maintenance therapy and small cell lung cancer, meeting primary endpoints in the FLAMES study for superior efficacy and safety. Other assets include WEE1 inhibitor IMP7068, ATR inhibitor IMP9064, and PARP1-selective inhibitor IMP1734 (collaborating with Eikon Therapeutics), alongside additional DDR inhibitors.

Key facts about Impact Therapeutics

Developer of solutions for diagnosing and treating lung disease. The company has developed the Archimedes navigation bronchoscopy system, which includes BTPNA (Bronchoscopic Trans-Parenchymal Nodule Access) that combines state-of-the-art nodule, vessel, and airway mapping, pathway guidance, and augmented fluoroscopic imaging enabling unprecedented biopsy and therapeutic access to any location in the lung. It also offer InterVapor Bronchoscopic Thermal Vapor Ablation is a non-surgical, non-implant therapy designed to improve lung function.

Key facts about Broncus

Provider of early cancer screening and testing services. The company has developed a fecal gene analysis (FIT-DNA) technology for colorectal cancer screening. The company also has a product for gastric cancer detection through their Helicobacter pylori toxicity factor detection technology. The company leverages its expertise in genetic testing, molecular diagnostics, and large data platforms and software in developing early detection tests for cancer.

Key facts about Zhejiang Nuhui Health Technology

Exome Asset Management's Investments by Stage

Exome Asset Management has made 4 investments in Post IPO stage with an average round size of $31M, 2 investments in Series D stage with an average round size of $20M and 1 investment in Series G stage.
Here are Exome Asset Management's investments by stage:
Stage of entry
No. of Investments
Post IPO
4
Series D
2
Series G
1
Breakdown of Exome Asset Management's investments by stage of entryPost IPO (4)Series D (2)
Note: We have considered here, only first round of investments

Exome Asset Management's Investments by Sector

Exome Asset Management has a diverse portfolio, with companies operating in the Life Sciences, Enterprise Applications and High Tech. Notably, it has invested in 7 Enterprise (B2B) companies, 7 Tech companies, 1 Saas company and at least 1 company focusing on Software.
Here are Exome Asset Management's investments by sector:
Sector
No. of Investments
Life Sciences
7
Enterprise Applications
1
High Tech
1
Breakdown of Exome Asset Management's investments by sectorsLife Sciences (7)Enterprise Applic... (1)
Note: We have considered here, only first round of investments

Exome Asset Management's Investments by Geography

Exome Asset Management has made most investments in United States (4), followed by China where it has made 3 investments.
Here are Exome Asset Management's investments by geography:
Country
No. of Investments
United States
4
China
3
Sweden
1
Breakdown of Exome Asset Management's investments by countriesUnited States (4)China (3)
Note: We have considered here, only first round of investments

Exome Asset Management's recent investments

Exome Asset Management has not made any investment in 2026 so far.
Here are the most recent investments by Exome Asset Management:
Date
Company
Location
Round Details
Round Amount
Co-Investors
Nov 12, 2025
United States
Post IPO
1897
Mar 11, 2024
United States
Post IPO
7417
Aug 07, 2023
China
Post IPO
5298
Mar 14, 2022
China
Series D
8007
Jan 28, 2021
United States
Series G
9904

IPOs and Publicly Listed companies in Exome Asset Management's Portfolio

6 of Exome Asset Management's portfolio companies have become public. Impact Therapeutics got listed on the Hong Kong Exchanges (HKG), in May 2026 at marketcap of $710M and Broncus got listed on the Hong Kong Exchanges (HKG) at marketcap of $1.26B.
Here are Exome Asset Management's portfolio companies that went public:
Company
IPO Date
First Invested on
First Round of Investment
Round Size
May 13, 2026
Mar 14, 2022
Series D
5265
Sep 24, 2021
Jan 28, 2021
Series G
9689
Feb 18, 2021
Apr 21, 2020
Series D
8201
Oct 03, 2019
Mar 11, 2024
Post IPO
7957
May 09, 2019
Nov 12, 2025
Post IPO
5050

Acquired companies in Exome Asset Management's Portfolio

1 company from Exome Asset Management's portfolio has been acquired. The most recent acquisition was Gracell Bio in Dec 2023 by AstraZeneca for $*****.
Here are Exome Asset Management's portfolio companies that got acquired most recently:
Company
Acquisition Date
First Invested on
First Round of Investment
Round Size
Dec 26, 2023
Aug 07, 2023
Post IPO
2932

Team profile of Exome Asset Management

Exome Asset Management has a team of 7 members located in United States. Exome Asset Management's team does not sit on the board of any company as of now.

Co-investors of Exome Asset Management

Over the past 6 years, 104 investors have co-invested in Exome Asset Management's portfolio companies. This includes only funds.

  • Invested before Exome Asset Management: Lilly Asia Ventures, 6 Dimensions Capital and 69 others have invested in rounds before Exome Asset Management. There are 3 companies where Lilly Asia Ventures has invested before Exome Asset Management and 3 companies where 6 Dimensions Capital has invested before Exome Asset Management.
  • Top Co-investors of Exome Asset Management: 24 investors entered a company along with Exome Asset Management. These include investors like Ikarian Capital (1 company).
  • Invested after Exome Asset Management: A total of 9 investors have invested in Exome Asset Management's portfolio after their investments. Top Investors include ShenZhen GTJA Investment Group (1 company) and Xicheng Jinrui (1 company).

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