About E12 Ventures
E12 Ventures is a venture capital firm founded in 2022. It is primarily based out of California City, United States. As of Aug 2026, E12 Ventures is an active investor, having invested in 11 companies, with 3 new investments in the last 12 months. It primarily invests in Series A round in United States based startups. Its investments are spread across a wide range of sectors from High Tech to HealthTech and Retail. Most recently it participated in the $***** Series B round of Reframe Systems A lot of funds co-invest with E12 Ventures, with names like IAG Capital Partners sharing a substantial percentage of its portfolio. E12 Ventures has team of 10 people including 5 partners.Key Metrics
Team Members
Portfolio Count
Portfolio Sectors
Portfolio Locations
Rounds of Entry
Series A & Series B
Deals in last 12 months
E12 Ventures' List of Top Investments
E12 Ventures has a portfolio of 11 companies. Their most notable investments include Archetype AI and unspun.Their portfolio spans across and United States. They have invested in High Tech, HealthTech, Retail and 9 other sectors, across stages such as Series A, Series B stages. Here is the list of top investments by E12 Ventures:
1. Archetype AI
Platform developing physical AI. Its model can perceive and reason about the physical world by fusing multimodal sensor data and natural language. The platforms approach involves sensor fusion, integrating information from multiple sensor modalities like radars, cameras, accelerometers, and more to analyze unstructured sensor data and uncover hidden patterns of behavior.
Key facts about Archetype AI
- Founded Year: 2023
- Location: Palo Alto (United States)
- Stage: Series A
- Total Funding till date: $48M
- Employee Count: 73 as on Sep 30, 2026
- Investors: IAG Capital Partners, Bezos Expeditions and 9 Others
- Latest Funding Round: Series A, Nov 20, 2025, $*****
- Highlight: Editors' Pick

2. unspun
Internet first brand offering jeans for men and women. The company provides a 3D body scanning solutions which enables users to customize and design the jeans by choosing styles, fabrics, stitch colors, and more. The company claims that the products are made by using 3D woven technology and more.
Key facts about unspun
- Founded Year: 2015
- Location: San Francisco (United States)
- Stage: Series B
- Total Funding till date: $70.9M
- Employee Count: 80 as on Sep 30, 2026
- Investors: DCVC, Prelude Ventures and 26 Others
- Latest Funding Round: Series B, Jul 20, 2026, $*****
- Highlight: Editors' Pick

3. Neura Health
Mobile app offering remote consulting services with neurologists. The app helps users to book online appointments with neurologists for headache and migraine pain consultation. Users can seek medical guidance and order their prescribed medicines using the app.
Key facts about Neura Health
- Founded Year: 2020
- Location: New York (United States)
- Stage: Series A
- Total Funding till date: $22M
- Employee Count: 55 as on Sep 30, 2026
- Investors: Global Founders Capital, Norwest and 13 Others
- Latest Funding Round: Series A, Sep 29, 2025, $*****
- Highlight: Editors' Pick
Provider of an AI-based app for behavioral health monitoring. The platform uses AI to capture a conversation between the patient and the doctor during a clinic visit. The platform uses deep learning algorithms to process the speech and to monitor and provide real-time behavioral health assessments that are shared with the healthcare providers. The platform monitors patients suffering from depression, anxiety, and other behavioral health issues.
Key facts about Ellipsis Health
- Founded Year: 2017
- Location: San Francisco (United States)
- Stage: Series A
- Total Funding till date: $75M
- Employee Count: 102 as on Sep 30, 2026
- Investors: AME Cloud Ventures, Salesforce and 26 Others
- Latest Funding Round: Series A, Jun 12, 2025, $*****
- Highlight: Editors' Pick

5. Ciba Health
Provider of teleconsultation and digital therapeutic software for employees and patients. The company has developed a virtual consultation and personalized digital therapeutic solution that connects providers with patients/employees. The platform has features for tracking health vitals by integrating smart devices with the software, share health reports with providers, and more.
Key facts about Ciba Health
- Founded Year: 2019
- Location: New York City (United States)
- Stage: Series A
- Total Funding till date: $21.5M
- Employee Count: 58 as on Sep 30, 2026
- Investors: Plug and Play Tech Center, E12 Ventures and 2 Others
- Latest Funding Round: Series A, Sep 26, 2025, $*****
- Highlight: Editors' Pick
E12 Ventures' Year-on-Year Investment Trends
In 2025, it made 3 investments, while as of Aug 2026, it has made 2 investments in this year. Its most recent first time investment was in Reframe Systems.Year | No. of Investments | ||
|---|---|---|---|
1st Round | Follow-on | Total | |
2026 (YTD) | 2 | 0 | 2 |
2025 | 3 | 0 | 3 |
2024 | 4 | 0 | 4 |
E12 Ventures' Investments by Stage
E12 Ventures has made 7 investments in Series A stage with an average round size of $23M and 2 investments in Series B stage with an average round size of $37.5M.Stage of entry | No. of Investments |
|---|---|
Series A | 7 |
Series B | 2 |
Note: We have considered here, only first round of investments
E12 Ventures' Investments by Sector
E12 Ventures has a diverse portfolio, with companies operating in the Enterprise Applications, HealthTech, High Tech, Consumer and Consumer Goods. Notably, it has invested in 10 Tech companies, 8 Enterprise (B2B) companies, 7 Software companies and at least 5 companies focusing on Consumer (B2C).Sector | No. of Investments |
|---|---|
Enterprise Applications | 4 |
HealthTech | 3 |
High Tech | 2 |
Consumer | 1 |
Consumer Goods | 1 |
Others | 5 |
Note: We have considered here, only first round of investments
E12 Ventures' Investments by Geography
E12 Ventures has made most investments in United States (9).E12 Ventures' recent investments
E12 Ventures has made 2 investments in 2026 so far - Reframe Systems and Mundo AI.Here are the most recent investments by E12 Ventures:
Date | Company | Location | Round Details | Round Amount | Co-Investors |
|---|---|---|---|---|---|
Aug 31, 2026 | United States | Series B | 7406 | ||
Aug 25, 2026 | United States | Series A | 7202 | [+2] | |
Nov 20, 2025 | United States | Series A | 8407 | [+7] | |
Sep 29, 2025 | United States | Series A | 6729 | ||
Jun 12, 2025 | United States | Series A | 8964 | [+4] |
Team profile of E12 Ventures
E12 Ventures has a team of 10 members including 5 Partners and 3 Principals located in United States. E12 Ventures' team does not sit on the board of any company as of now.Here is a list of all team members in E12 Ventures:
Name | Designation | Location | Board Memberships | Contact Details |
|---|---|---|---|---|
Partner | San Francisco | - | ||
Partner | San Francisco | - | ||
Partner | San Francisco | - | ||
Partner | Pleasanton | - | ||
Partner | San Francisco | - | ||
Principal | Menlo Park | - | - | |
Principal | San Francisco | - | ||
Principal | Menlo Park | - |
Co-investors of E12 Ventures
Over the past 2 years, 98 investors have co-invested in E12 Ventures's portfolio companies. This includes funds and angels.
- Invested before E12 Ventures: Alumni Ventures, Plug and Play Tech Center and 63 others have invested in rounds before E12 Ventures. There are 2 companies where Alumni Ventures has invested before E12 Ventures and 2 companies where Plug and Play Tech Center has invested before E12 Ventures.
- Top Co-investors of E12 Ventures: 33 investors entered a company along with E12 Ventures. These include investors like IAG Capital Partners (1 company).
Recent News related to E12 Ventures
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Mundo AI Secures $20 Million Series A Funding Led by GreatPoint Ventures for AI Infrastructure ExpansionThe SaaS News•Aug 26, 2026•Mundo AI, Next Frontier Capital, Y Combinator, E12 Ventures
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Archetype AI Raises $35M to Scale Deployment of Physical Agents to Solve Real-World ProblemsBusiness Wire•Nov 20, 2025•Archetype AI, Hitachi Ventures, International Airlines Group, Bezos Expeditions and 10 others
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Neura Health Secures $11.4 Million Series A for National ExpansionBenzinga•Sep 29, 2025•Neura Health, American Heart Association, E12 Ventures, Koch Disruptive Technologies and 3 others
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Ellipsis Health unveils Sage, the emotionally intelligent AI Care Manager, backed by $45M fundingPR Newswire•Jun 12, 2025•Ellipsis Health, Salesforce, Khosla Ventures, CVS Health Ventures and 4 others
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First Resonance Secures Major Investment to Drive Digital Manufacturing with ION Factory OSintelligence360•Jan 09, 2025•First Resonance, Third Prime, Craft Ventures, Blue Bear Capital and 3 others
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First Resonance Raises $12.5MLos Angeles Business Journal•Dec 23, 2024•First Resonance, Third Prime, Craft Ventures, Blue Bear Capital and 1 other
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One Bio Raises $27M to Advance Short-Chain Fiber Ingredients for GLP-1 Friendly FoodsThe Spoon•Dec 12, 2024•One bio, Alpha Edison, Leaps by Bayer, E12 Ventures and 8 others
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unspun: 3D Weaving Company Secures $32 Million (Series B)Pulse 2.0•Aug 11, 2024•unspun, DCVC, Lowercarbon Capital, E12 Ventures and 1 other
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