About Osage University Partners
Osage University Partners is a venture capital firm founded in 2009. It is primarily based out of Bala Cynwyd, United States. As of May 2026, Osage University Partners is an active investor, having invested in 146 companies, with 4 new investments in the last 12 months. It primarily invests in Series A round in United States based startups. Its investments are spread across a wide range of sectors from Life Sciences to High Tech and Enterprise Applications. Most recently it participated in the $***** Series A round of Tessera Labs Overall, Osage University Partners portfolio has seen 1 unicorn, 24 IPOs and 37 acquisitions including key companies like Guardant Health, IonQ and Sana Biotechnology. A lot of funds co-invest with Osage University Partners, with names like Orbimed sharing a substantial percentage of its portfolio. Osage University Partners has team of 15 people including 7 partners.Key Metrics
Team Members
Portfolio Count
Portfolio Sectors
Portfolio Locations
Rounds of Entry
Series A, Series B & 4 more
Portfolio IPOs
Portfolio Acquisitions
Portfolio Unicorns
Portfolio Soonicorns
Deals in last 12 months
Osage University Partners' List of Top Investments
Osage University Partners has a portfolio of 146 companies, one of which is a Unicorn. Their most notable investments are in Embodied and ESCAPE Bio.Their portfolio spans across United States, United Kingdom, Israel and 1 more locations. They have invested in Life Sciences, High Tech, Enterprise Applications and 24 other sectors, across stages such as Series A, Series B and 4 more. Here is the list of top investments by Osage University Partners:
Developer of digital sequencing technology for cancer detection. The product Guardant360 offers real-time, biopsy-free tumor sequencing for the analysis and identification of tumor-associated treatment options. Also, it has developed analytical tools, including a tumor response map and a mobile-enabled physician portal.
Key facts about Guardant Health
- Founded Year: 2012
- Location: Redwood City (United States)
- Annual Revenue: $500M - $1B as on Dec 31, 2025
- Stage: Public
- Total Funding till date: $557M
- Employee Count: 4,601 as on May 31, 2026
- Investors: Acquisition Group, Hone Capital and 25 Others
- Latest Funding Round: Post IPO, Nov 05, 2025, $*****
- Highlight: Public
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2. IonQ
Provider of cloud and trapped ion technology-based universal quantum computers. It provides users with a company that offers quantum computer that traps individual ionized ytterbium atoms in a 3D space and uses lasers for computation purposes.
Key facts about IonQ
- Founded Year: 2015
- Location: College Park (United States)
- Annual Revenue: $10M - $50M as on Dec 31, 2024
- Stage: Public
- Total Funding till date: $86M
- Employee Count: 1,020 as on Apr 30, 2026
- Investors: Silver Lake, Samsung Catalyst Fund and 23 Others
- Latest Funding Round: Series B, Jun 16, 2020, $*****
- Highlight: Public
Developer of engineered cell therapies for treating various human diseases. Research focuses on repairing or controlling genes within cells and replacing damaged or missing cells to address underlying disease causes. Drug candidates target conditions including diabetes, cancers, and autoimmune disorders. The work involves cellular biology and machine learning to create therapeutic interventions.
Key facts about Sana Biotechnology
- Founded Year: 2018
- Location: Seattle (United States)
- Stage: Public
- Total Funding till date: $821M
- Employee Count: 259 as on May 31, 2026
- Investors: HTIF, Baillie Gifford and 17 Others
- Latest Funding Round: Series D, Jun 25, 2020, $*****
- Highlight: Public
Provider of cloud-delivered browser security solutions for enterprise threat and data protection. It transforms any browser into a secure enterprise browser through cloud-based digital twins. The solution prevents zero-day exploits, phishing, and ransomware from reaching networks or endpoints. It offers secure access for managed and unmanaged devices, eliminating VPN risks and VDI complexity. The platform delivers file security through content disarm and reconstruction, antivirus, and sandboxing.
Key facts about Menlo Security
- Founded Year: 2013
- Location: Mountain View (United States)
- Annual Revenue: £1M - £10M as on Dec 31, 2017
- Valuation: $*****
- Stage: Series E
- Total Funding till date: $250M
- Employee Count: 462 as on May 31, 2026
- Investors: Company Capital, Fabrica Ventures and 12 Others
- Latest Funding Round: Series E, Dec 10, 2023, $*****
- Highlight: Editors' Pick
5. SiFive
Provider of customizable RISC-V processor IP and high-performance compute core solutions for AI. It delivers scalable and configurable CPU core solutions including scalar, vector, and matrix computing designs. It enables chip designers and system developers to build high-performance, energy-efficient computing solutions across domains such as AI/ML, automotive systems, edge computing, data centers, and embedded devices. It focuses on enabling customization, rapid innovation, and performance optimization through modular processor IP, supporting applications that require flexible compute architectures and advanced workload acceleration.
Key facts about SiFive
- Founded Year: 2015
- Location: Santa Clara (United States)
- Valuation: $*****
- Stage: Series G
- Total Funding till date: $766M
- Employee Count: 501 as on May 31, 2026
- Investors: T. Rowe Price, Spark Capital and 26 Others
- Latest Funding Round: Series G, Apr 09, 2026, $*****
- Highlight: Editors' Pick
Osage University Partners' Year-on-Year Investment Trends
Osage University Partners has invested in 146 companies over the last 17 years, with an average of 7 new investments annually in the last 10 years. In 2025, it made 6 investments, while as of May 2026, it has made 3 investments in this year. Its most recent first time investment was in Tessera Labs and most recent follow-on round was in Nocion Therapeutics.Year | No. of Investments | ||
|---|---|---|---|
1st Round | Follow-on | Total | |
2026 (YTD) | 3 | 0 | 3 |
2025 | 2 | 4 | 6 |
2024 | 6 | 3 | 9 |
2023 | 4 | 2 | 6 |
2022 | 6 | 2 | 8 |
2021 | 8 | 6 | 14 |
2020 | 7 | 7 | 14 |
2019 | 9 | 8 | 17 |
2018 | 11 | 6 | 17 |
2017 | 13 | 7 | 20 |
Osage University Partners' Investments by Stage
Osage University Partners has made 51 investments in Series A stage with an average round size of $36M, 32 investments in Series B stage with an average round size of $54.2M and 15 investments in Series C stage with an average round size of $56.4M.Stage of entry | No. of Investments |
|---|---|
Series A | 51 |
Series B | 32 |
Series C | 15 |
Seed | 8 |
Series D | 3 |
Others | 1 |
Note: We have considered here, only first round of investments
Osage University Partners' Investments by Sector
Osage University Partners has a diverse portfolio, with companies operating in the Life Sciences, High Tech, Enterprise Applications, Semiconductors and Enterprise Infrastructure. Notably, it has invested in 132 Enterprise (B2B) companies, 132 Tech companies, 47 Software companies and at least 26 companies focusing on Tech hardware.Sector | No. of Investments |
|---|---|
Life Sciences | 69 |
High Tech | 31 |
Enterprise Applications | 27 |
Semiconductors | 11 |
Enterprise Infrastructure | 7 |
Others | 60 |
Note: We have considered here, only first round of investments
Osage University Partners' Investments by Geography
Osage University Partners has made most investments in United States (106), followed by United Kingdom where it has made 2 investments.Country | No. of Investments |
|---|---|
United States | 106 |
United Kingdom | 2 |
Israel | 1 |
Singapore | 1 |
Note: We have considered here, only first round of investments
Osage University Partners' recent investments
Osage University Partners has made 3 investments in 2026 so far. Tessera Labs and Terremoto are the latest among them.Here are the most recent investments by Osage University Partners:
Filter this listDate | Company | Location | Round Details | Round Amount | Co-Investors |
|---|---|---|---|---|---|
May 05, 2026 | United States | Series A | 2471 | [+2] | |
Apr 10, 2026 | United States | Series C | 4037 | ||
Mar 06, 2026 | United States | Series A | 4297 | [+9] | |
Dec 15, 2025 | United States | Series B | 3335 | [+8] | |
Dec 11, 2025 | United States | Series D | 6506 | [+4] |
Unicorns in Osage University Partners' Portfolio
Osage University Partners has 1 unicorn in its portfolio - SiFive. The most recent unicorn in their portfolio is SiFive which became a unicorn in 2022, 4 years after Osage University Partners first invested in it.Here is a list of unicorns in Osage University Partners' portfolio:
Tracxn Score | Company | Short Description | Founded year | Sector | Location | Company Stage | First Investment/ Acquisition Details |
|---|---|---|---|---|---|---|---|
71 | Provider of customizable RISC-V processor IP and high-performance compute core solutions for AI | 2015 | Santa Clara | Series G | ldwoatr |
IPOs and Publicly Listed companies in Osage University Partners' Portfolio
24 of Osage University Partners' portfolio companies have become public. Mobia Medical got listed on the National Association of Securities Dealers Automated Quotations (NASDAQ), in May 2026 at marketcap of $496M and VeraDermics got listed on the New York Stock Exchange (NYSE) at marketcap of $567M.Here are Osage University Partners' portfolio companies that went public:
Company | IPO Date | First Invested on | First Round of Investment | Round Size |
|---|---|---|---|---|
May 08, 2026 | - | - | 6306 | |
Feb 04, 2026 | Dec 11, 2024 | Series B | 2662 | |
Jul 30, 2025 | - | - | 8176 | |
Sep 26, 2024 | Feb 13, 2024 | Series D | 9306 | |
Oct 20, 2022 | - | - | 4404 |
Acquired companies in Osage University Partners' Portfolio
37 companies from Osage University Partners' portfolio have been acquired. The most recent acquisition was Quantum Circuits in Jan 2026 by D-Wave for $*****.Here are Osage University Partners' portfolio companies that got acquired most recently:
Company | Acquisition Date | First Invested on | First Round of Investment | Round Size |
|---|---|---|---|---|
Jan 07, 2026 | Nov 13, 2017 | Series A | 6476 | |
Aug 21, 2025 | May 18, 2021 | Series A | 3229 | |
Nov 22, 2024 | Jun 08, 2023 | Series A | 1058 | |
Apr 23, 2024 | May 09, 2018 | Series A | 6163 | |
Mar 25, 2024 | Aug 23, 2019 | Series B | 6981 |
Team profile of Osage University Partners
Osage University Partners has a team of 15 members including 7 Partners and 3 Principals located in United States. Osage University Partners' team does not sit on the board of any company as of now.Here is a list of top team members in Osage University Partners:
Name | Designation | Location | Board Memberships | Contact Details |
|---|---|---|---|---|
Partner | Boston | - | ||
Partner | Bala Cynwyd | - | ||
Partner | Naples | - | ||
Partner | Philadelphia | - | ||
Partner | Philadelphia | - | ||
Partner | - | - | ||
Partner | Philadelphia | - | ||
Principal | New York | - | ||
Principal | Cambridge | - | ||
Principal | Philadelphia | - |
Co-investors of Osage University Partners
Over the past 17 years, 844 investors have co-invested in Osage University Partners's portfolio companies. This includes funds and angels.
- Invested before Osage University Partners: HHS, Orbimed and 222 others have invested in rounds before Osage University Partners. There are 6 companies where HHS has invested before Osage University Partners and 6 companies where Orbimed has invested before Osage University Partners.
- Top Co-investors of Osage University Partners: 338 investors entered a company along with Osage University Partners. These include investors like Orbimed (10 companies).
- Invested after Osage University Partners: A total of 282 investors have invested in Osage University Partners's portfolio after their investments. Top Investors include New Enterprise Associates (4 companies), RA Capital Management (4 companies) and Wellington (4 companies).
Recent News related to Osage University Partners
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Tessera Labs Secures $60 Million in Oversubscribed Funding Round Led by Andreessen HorowitzThe SaaS News•May 07, 2026•Tessera Labs, Myriad Venture Partners, Osage University Partners, Andreessen Horowitz and 1 other
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Terremoto Biosciences Raises $108M in Series C FundingFinSMEs•Apr 15, 2026•Terremoto, RA Capital Management, Deep Track Capital, Cormorant-asset and 4 others
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Addition Therapeutics Announces $100 Million Funding for Genomic MedicineBenzinga•Dec 17, 2025•Abingworth, Addition Therapeutics, SR One, Pivotal Life Sciences and 3 others
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Virtue AI Raises $30 Million in Seed and Series A Funding to Bridge the Critical AI Security GapBakersfield•Apr 15, 2025•Virtue AI, Lightspeed Venture Partners, Walden Catalyst, Osage University Partners and 3 others
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Atsena Therapeutics Raises $150M in Series C FinancingFinSMEs•Apr 04, 2025•Atsena Therapeutics, Bain Capital Life Sciences, Wellington, Lightstone Ventures and 6 others
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MicroTransponder receives $65m to advance stroke care with VivistimMedicalDeviceNetwork•Mar 13, 2025•MicroTransponder, Usventure, Exceller Hunt, Green Park & Golf Ventures and 6 others
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MicroTransponder Secures $65 Million to Enhance Vivistim Adoption for Chronic Stroke RecoveryPR Newswire•Mar 12, 2025•MicroTransponder, Usventure, USVP, Osage Partners and 7 others
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Overland AI Raises $32 Million to Advance Ground Autonomy for DefenseMaginative•Jan 14, 2025•Overland, 8VC, Point72 Ventures, Overmatch and 5 others
