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About Prospect Venture Partners

Prospect Venture Partners is a venture capital firm founded in 1997. It is primarily based out of Palo Alto, United States. As of Oct 2016, Prospect Venture Partners has invested in 53 companies. It primarily invests in Series B round in United States based startups. Its investments are spread across a wide range of sectors from Life Sciences to High Tech and Enterprise Applications. Most recently it participated in the $***** Series D round of SentreHEART Overall, Prospect Venture Partners portfolio has seen 7 IPOs and 28 acquisitions including key companies like Jazz Pharmaceuticals, Insmed and Complete Genomics. A lot of funds co-invest with Prospect Venture Partners, with names like Rho Capital Partners sharing a substantial percentage of its portfolio. Prospect Venture Partners has team of 3 people including 3 partners.
Key Metrics
Portfolio Sectors
Portfolio Locations
Rounds of Entry
Series B, Series A & 3 more
Portfolio Soonicorns

Prospect Venture Partners' List of Top Investments

Prospect Venture Partners has a portfolio of 53 companies. Their most notable investments are in Complete Genomics and Pathwork Diagnostics.Their portfolio spans across United States, Belgium, China and 1 more locations. They have invested in Life Sciences, High Tech, Enterprise Applications and 9 other sectors, across stages such as Series B, Series A  and 3 more. Here is the list of top investments by Prospect Venture Partners:
Developer of novel biopharmaceutical medicines for unmet medical needs. It focuses on developing and delivering life-changing medications to patients with limited or no treatment options. The company's pipeline includes various therapeutic areas, and it supports its medicines with robust clinical trial programs and patient support resources. Research efforts prioritize patient needs, driving advancements in understanding and treating specific conditions. The company also engages in corporate giving and sustainability initiatives.

Key facts about Jazz Pharmaceuticals

  • Founded Year: 2003
  • Location: Dublin (Ireland)
  • Annual Revenue: $500M - $1B as on Dec 31, 2020
  • Stage: Public
  • Total Funding till date: $265M
  • Employee Count: 3,648 as on Jul 31, 2026
  • Investors: Adams Street Partners, Thoma Bravo and 14 Others
  • Latest Funding Round: Post IPO, Jul 07, 2009, $*****
  • Highlight: Public
Developer of small molecule inhibitors for rare lung diseases. Its lead candidate is Arikayce (liposomal amikacin for inhalation), a ribosomal 30S subunit inhibitor for nontuberculous mycobacteria (NTM) lung disease. It also has an earlier-stage clinical pipeline which includes INS1009, a nebulized prodrug formulation of treprostinil that claims to have potential in rare pulmonary disorders such as pulmonary arterial hypertension (PAH), idiopathic pulmonary fibrosis (IPF) sarcoidosis, and severe refractory asthma.

Key facts about Insmed

Complete Genomics is a developer of DNA sequencing platform for human genome sequencing and analysis. It has developed a DNA sequencing platform based on its proprietary DNA nanoball sequencing technology. It is a method of rolling cycle replication to clonally amplify small fragments of DNA into DNA nanoballs which are then attached to a microarray flow cell and sequenced. The sequencing generates fragment lengths of 250-500 bp (mate pair distance), which can then be analyzed using proprietary algorithms. The company's platform is called the Revolocity Platform and is optimized for the Human whole genome and whole exome sequencing. The company also provides analysis and data management software for generating finished variant reports and assemblies.

Key facts about Complete Genomics

Developer of nanotechnology-based displays. It provides quantum dots and nanometer-sized crystals for creating LED display systems. It is more energy-efficient, more responsive, and brighter than traditional display technology.

Key facts about Nanosys

Developer of novel vaccines for the treatment of infectious diseases. Its pipeline includes a vaccine for respiratory syncytial virus infection, coronavirus, malaria, ebola, and seasonal quadrivalent vaccines for influenza. It uses recombinant nanoparticles and adjuvant technology.

Key facts about Novavax

Prospect Venture Partners' Investments by Stage

Prospect Venture Partners has made 18 investments in Series B stage with an average round size of $28.4M, 12 investments in Series A stage with an average round size of $25.1M, 7 investments in Series C stage with an average round size of $29.4M, 2 investments in Series D stage with an average round size of $31.1M and 1 investment in PE stage with an average round size of $200M.
Here are Prospect Venture Partners' investments by stage:
Stage of entry
No. of Investments
Series B
18
Series A
12
Series C
7
Series D
2
PE
1
Breakdown of Prospect Venture Partners' investments by stage of entrySeries B (18)Series A (12)
Note: We have considered here, only first round of investments

Prospect Venture Partners' Investments by Sector

Prospect Venture Partners has a diverse portfolio, with companies operating in the Life Sciences, High Tech, Consumer, Sustainability Tech and Healthcare. Notably, it has invested in 42 Tech companies, 33 Enterprise (B2B) companies, 11 Software companies and at least 9 companies focusing on Consumer (B2C).
Here are Prospect Venture Partners' investments by sector:
Sector
No. of Investments
Life Sciences
34
High Tech
4
Consumer
3
Sustainability Tech
3
Healthcare
2
Others
7
Breakdown of Prospect Venture Partners' investments by sectorsLife Sciences (34)High Tech (4)
Note: We have considered here, only first round of investments

Prospect Venture Partners' Investments by Geography

Prospect Venture Partners has made most investments in United States (37), followed by Belgium where it has made 1 investment.
Here are Prospect Venture Partners' investments by geography:
Country
No. of Investments
United States
37
Belgium
1
China
1
Ireland
1
Breakdown of Prospect Venture Partners' investments by countriesUnited States (37)Belgium (1)
Note: We have considered here, only first round of investments

Prospect Venture Partners' recent investments

Prospect Venture Partners has not made any investment in 2026 so far.
Here are the most recent investments by Prospect Venture Partners:
Date
Company
Location
Round Details
Round Amount
Co-Investors
Oct 14, 2016
United States
Series D
6730
  [+3]
Feb 23, 2015
United States
Series D
3019
Apr 22, 2014
United States
Series B
3048
Mar 18, 2014
United States
Series B
2422
Jul 18, 2013
United States
Series C
4266

IPOs and Publicly Listed companies in Prospect Venture Partners' Portfolio

7 of Prospect Venture Partners' portfolio companies have become public. Idun Pharmaceuticals got listed on the Stockholm Stock Exchange (STO), in Mar 2021 and NGM Biopharmaceuticals got listed on the National Association of Securities Dealers Automated Quotations (NASDAQ) at marketcap of $1.04B.
Here are Prospect Venture Partners' portfolio companies that went public:
Company
IPO Date
First Invested on
First Round of Investment
Round Size
Mar 26, 2021
Jun 14, 2004
Series B
8440
Apr 05, 2019
Feb 11, 2008
Series A
6762
Jun 01, 2007
Apr 2003
Series A
1076
Apr 12, 2006
Oct 2004
Series B
4196
Jul 28, 2000
-
-
1698

Acquired companies in Prospect Venture Partners' Portfolio

28 companies from Prospect Venture Partners' portfolio have been acquired. The most recent acquisition was Complete Genomics in Feb 2026 by Swiss Rockets for $*****.
Here are Prospect Venture Partners' portfolio companies that got acquired most recently:
Company
Acquisition Date
First Invested on
First Round of Investment
Round Size
Feb 23, 2026
Mar 31, 2008
Series C
4075
Dec 19, 2025
May 12, 2004
Series B
6795
Oct 18, 2022
Oct 2003
Series B
7934
Oct 18, 2022
Feb 15, 2002
Series B
9187
May 05, 2020
Dec 08, 2003
Series A
7893

Team profile of Prospect Venture Partners

Prospect Venture Partners has a team of 3 members including 3 Partners located in United States. Prospect Venture Partners' team does not sit on the board of any company as of now.
Here is a list of all team members in Prospect Venture Partners:
Name
Designation
Location
Board Memberships
Contact Details
Partner
Palo Alto
-
-
Partner
Atlantic City
-
-
Partner
United States
-
-

Co-investors of Prospect Venture Partners

Over the past 24 years, 203 investors have co-invested in Prospect Venture Partners's portfolio companies. This includes only funds.

  • Invested before Prospect Venture PartnersArch Venture Partners, Venrock and 27 others have invested in rounds before Prospect Venture Partners. There are 3 companies where Arch Venture Partners has invested before Prospect Venture Partners and 2 companies where Venrock has invested before Prospect Venture Partners.
  • Top Co-investors of Prospect Venture Partners77 investors entered a company along with Prospect Venture Partners. These include investors like Rho Capital Partners (5 companies).
  • Invested after Prospect Venture PartnersA total of 97 investors have invested in Prospect Venture Partners's portfolio after their investments. Top Investors include Orbimed (2 companies), HBM Healthcare Investments (2 companies) and New Enterprise Associates (2 companies).

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