About SeedFolio
SeedFolio is a venture capital firm founded in 2020. It is primarily based out of San Diego, United States. As of Sep 2024, SeedFolio has invested in 52 companies. It primarily invests in Seed round in United States based startups. Its investments are spread across a wide range of sectors from Life Sciences to HealthTech and Enterprise Applications. Most recently it participated in the $***** Seed round of HDAX Overall, SeedFolio portfolio has seen 3 acquisitions, namely S2 Genomics, Allotrope Medical and Echo Laboratories. A lot of funds co-invest with SeedFolio, with names like NuFund sharing a substantial percentage of its portfolio. SeedFolio has team of 7 people including 5 partners.Key Metrics
Team Members
Portfolio Count
Portfolio Sectors
Portfolio Locations
Rounds of Entry
Seed & Series A
Portfolio Acquisitions
Portfolio Soonicorns
SeedFolio's List of Top Investments
SeedFolio has a portfolio of 52 companies. Their most notable investments are in HDAX and Leap.Their portfolio spans across United States, Canada and Cayman Islands. They have invested in Life Sciences, HealthTech, Enterprise Applications and 15 other sectors, across stages such as Seed, Series A stages. Here is the list of top investments by SeedFolio:_1557407060666.png?format=webp&height=120&width=120){kind=logo}
Deep Blue is involved in developing a hernia mesh to address the high rate of hernia occurrence and recurrence. They have developed T-Line mesh and Anchor Clips that have the potential to reduce hernia occurrence and recurrence.
Key facts about Deep Blue Medical Advance
- Founded Year: 2015
- Location: Durham (United States)
- Stage: Series A
- Total Funding till date: $18.5M
- Employee Count: 12 as on Sep 30, 2026
- Investors: BayMed Venture Partners, Triangle Angel Partners and 5 Others
- Latest Funding Round: Series A, Sep 09, 2025, $*****
- Highlight: Editors' Pick
Developing innovative solutions to combat opioid overdose and reduce opioid abuse. This therapeutics company is dedicated to establishing new safety standards in the pharmaceutical industry, specifically addressing the opioid crisis. They focus on creating Safer Medicines that Alleviate Risks and Trauma (SMART) products. Their lead products include a rescue agent designed for synthetic opioid overdoses and an oral overdose protection system. These solutions aim to reduce opioid use disorder, prevent fatal overdoses, and effectively manage pain. The company leverages its expertise to develop novel chemical entities with the potential to receive breakthrough technology designation. They are seeking partners to support their mission of reducing suffering from pain, opioid use disorder, and fatal opioid overdose. Their work has a significant social impact, addressing a critical public health issue.
Key facts about Elysium Therapeutics
- Founded Year: 2013
- Location: San Francisco (United States)
- Stage: Series A
- Total Funding till date: $9.94M
- Employee Count: 4 as on Aug 31, 2026
- Investors: Mesa Verde Venture Partners, Innovations for Impact and 4 Others
- Latest Funding Round: Series A, Jan 28, 2026, $*****
- Highlight: Editors' Pick
3. VECKTA
Cloud-based microgrid turnkey control solutions provider. The platform helps its users to connect with right partners to design, finance and build microgrid or other distributed energy system. Other offerings include energy pricing, solar and wind data, vendor data and geospatial analysis.
Key facts about VECKTA
- Founded Year: 2019
- Location: San Diego (United States)
- Stage: Seed
- Total Funding till date: $3.3M
- Employee Count: 24 as on Sep 30, 2026
- Investors: VoLo Earth Ventures, Cove Fund and 7 Others
- Latest Funding Round: Seed, Jul 12, 2022, $*****
- Highlight: Editors' Pick
Developer of therapies for cardiovascular aging and vascular disease. The company's lead clinical candidate is VS-041, which is a potential personalized medicine-based treatment for heart failure with preserved ejection fraction. It also, develops pipeline for muscle atrophy and obesity.
Key facts about Vasa Therapeutics
- Founded Year: 2019
- Location: Encinitas (United States)
- Stage: Seed
- Employee Count: 14 as on Sep 30, 2026
- Investors: NuFund, SeedFolio and 1 Other
- Latest Funding Round: Seed, Jan 03, 2024, $*****
5. S2 Genomics
Developer of automated sample preparation systems for genomics. The company is developing single-cell sample preparations solutions for NGS. Their systems are used for processing tissues and liquid samples into genomic samples. The company is also developing a spatial sequencing technology that will capture the spatial location like 3-dimensional coordinates, of single cells in tissue for NGS readout.
Key facts about S2 Genomics
- Founded Year: 2016
- Location: Livermore (United States)
- Stage: Acquired
- Total Funding till date: $16M
- Employee Count: 5 as on Aug 31, 2026
- Investors: Tri-Valley Ventures, R42 Group and 6 Others
- Latest Funding Round: Series A, Jan 23, 2024, $*****
- Highlight: Acquired
SeedFolio's Year-on-Year Investment Trends
SeedFolio has invested in 52 companies over the last 5 years, with an average of 2 new investments annually in the last 5 years. Its most recent first time investment was in HDAX.Year | No. of Investments | ||
|---|---|---|---|
1st Round | Follow-on | Total | |
2026 (YTD) | 0 | 0 | 0 |
2025 | 0 | 0 | 0 |
2024 | 2 | 0 | 2 |
2023 | 4 | 0 | 4 |
2022 | 3 | 0 | 3 |
2021 | 1 | 0 | 1 |
SeedFolio's Investments by Stage
SeedFolio has made 9 investments in Seed stage with an average round size of $2.92M and 1 investment in Series A stage with an average round size of $5.05M.Stage of entry | No. of Investments |
|---|---|
Seed | 9 |
Series A | 1 |
Note: We have considered here, only first round of investments
SeedFolio's Investments by Sector
SeedFolio has a diverse portfolio, with companies operating in the Life Sciences, Blockchain Technology, Consumer, Energy and Energy Tech. Notably, it has invested in 42 Tech companies, 37 Enterprise (B2B) companies, 9 Software companies and at least 7 companies focusing on Consumer (B2C).Sector | No. of Investments |
|---|---|
Life Sciences | 8 |
Blockchain Technology | 1 |
Consumer | 1 |
Energy | 1 |
Energy Tech | 1 |
Others | 7 |
Note: We have considered here, only first round of investments
SeedFolio's Investments by Geography
SeedFolio has made most investments in United States (8), followed by Canada where it has made 2 investments.Country | No. of Investments |
|---|---|
United States | 8 |
Canada | 2 |
Note: We have considered here, only first round of investments
SeedFolio's recent investments
SeedFolio has not made any investment in 2026 so far.Here are the most recent investments by SeedFolio:
Filter this listDate | Company | Location | Round Details | Round Amount | Co-Investors |
|---|---|---|---|---|---|
Sep 05, 2024 | Canada | Seed | 1840 | [+3] | |
Jan 03, 2024 | United States | Seed | 1440 | [+1] | |
Dec 05, 2023 | United States | Seed | 9698 | [+1] | |
2023 | Canada | Seed | 2530 | [+4] | |
Mar 09, 2023 | United States | Seed | 9599 | [+9] |
Acquired companies in SeedFolio's Portfolio
3 companies from SeedFolio's portfolio have been acquired. The most recent acquisition was S2 Genomics.Here are SeedFolio's portfolio companies that got acquired most recently:
Company | Acquisition Date | First Invested on | First Round of Investment | Round Size |
|---|---|---|---|---|
Sep 17, 2025 | - | - | 8695 | |
Apr 01, 2023 | Apr 27, 2021 | Series A | 3032 | |
Jun 26, 2021 | - | - | 7387 |
Team profile of SeedFolio
SeedFolio has a team of 7 members including 5 Partners and 1 Principal located in United States. SeedFolio's team does not sit on the board of any company as of now.Here is a list of all team members in SeedFolio:
Name | Designation | Location | Board Memberships | Contact Details |
|---|---|---|---|---|
Partner | Walnut Creek | - | ||
Partner | - | - | ||
Partner | San Francisco | - | ||
Partner | Walnut Creek | - | ||
Partner | - | - | ||
Principal | San Francisco | - | - |
Co-investors of SeedFolio
Over the past 5 years, 61 investors have co-invested in SeedFolio's portfolio companies. This includes funds and angels.
- Invested before SeedFolio: America’s Seed Fund, Houston Health Ventures and 9 others have invested in rounds before SeedFolio. There is 1 company where America’s Seed Fund has invested before SeedFolio and 1 company where Houston Health Ventures has invested before SeedFolio.
- Top Co-investors of SeedFolio: 44 investors entered a company along with SeedFolio. These include investors like NuFund (4 companies).
- Invested after SeedFolio: A total of 6 investors have invested in SeedFolio's portfolio after their investments. Top Investors include Beiley Biofund (1 company), John Ballantyne (1 company) and Military Health (1 company).
Recent News related to SeedFolio
•
HDAX Therapeutics Announces First Closing of Oversubscribed US $3.2 (CA $4.3) Million Seed FinancingFinancial Post•Sep 05, 2024•HDAX, SeedFolio, Faceit, TIAP and 3 others
•
Vasa Therapeutics Announces Closing of Seed Financing to Advance Novel Therapies for Diseases of Cardiovascular AgingTullahoma News•Jan 03, 2024•Vasa Therapeutics, Orphinic, NuFund, SeedFolio and 1 other
•
Female-led biotech raises $2M to reduce the production cost of lab-grown meatTech Funding News•Mar 10, 2023•Tiamat Sciences, 8090 Industries, True Ventures, Social Impact Capital and 7 others
•
Tiamat Sciences Raises $2M Seed ExtensionFinSMEs•Mar 09, 2023•Tiamat Sciences, 8090 Industries, True Ventures, Social Impact Capital and 7 others
•
VerImmune Inc Announces Closing of Seed Financing to Further Develop Novel Virus-inspired Particle ImmunotherapiesPRWeb•Jul 28, 2022•VerImmune, SeedFolio, Ulu Ventures, Proxima Ventures and 3 others
•
•
•
Allotrope Medical Raises $4M in Series A FinancingFinSMEs•Jun 01, 2021•Allotrope Medical, Rockies Venture Club, Bellingham Angel Investors, Berkeley Angel Network and 6 others
