Ensoma - About the company
Ensoma is a series B company based in Boston (United States), founded in 2019 by Andre Lieber and Hans Peter Kiem. It operates as a Developer of in vivo hematopoietic stem cell engineering for genomic medicine. Ensoma has raised $205M in funding from 5AM Ventures and Arix Bioscience. The company has 664 active competitors, including 228 funded and 150 that have exited. Its top competitors include companies like Alnylam, Spark Therapeutics and Strand Therapeutics.
Company Details
Developer of in vivo hematopoietic stem cell engineering for genomic medicine. The company’s technology platform enables in vivo engineering of hematopoietic stem cells. It combines an off-the-shelf in vivo delivery system with a gene engineering toolkit. The vision is for a hematopoietic stem cell engineering platform that selectively and durably modifies cells of the hematopoietic system with the intent to treat diseases with versatility. The aim is to shape a new patient experience defined by simplicity, speed and safety.
- Website
- ensoma.com
- Email ID
- *****@ensoma.com
- Registered Address
- Boston (United States)
Key Metrics
Founded Year
2019
Location
Boston, United States
Stage
Series B
Total Funding
$205M in 3 rounds
Latest Funding Round
Investors
Ranked
64th among 664 active competitors
Employee Count
57 as on Apr 30, 2026
Investment & Acquisitions
Legal entities associated with Ensoma
Ensoma is associated with 1 legal entity given below:
Legal Entity Name | Date of Incorporation | Revenue | Latest Employee Count | Documents |
|---|---|---|---|---|
Ensoma, Inc. CIN: 84-2970518 , United States, Active | Dec 31, 2018 | - | 52 (As on Dec 31, 2021) | - |
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Ensoma's funding and investors
Ensoma has raised a total funding of $205M over 3 rounds. Its first funding round was on Feb 11, 2021. Its latest funding round was a Series B round on May 16, 2023 for $*****. 17 investors participated in its latest round. Ensoma has 20 institutional investors.
Here is the list of recent funding rounds of Ensoma:
Date of Funding | Funding Amount | Round Name | Post-Money Valuation | Revenue Multiple | Lead Investors | Other Investors |
|---|---|---|---|---|---|---|
May 16, 2023 | 1917538 | Series B | 9621131 | 6578597 | 2024843 | 9975706 |
Jan 05, 2023 | 9587026 | Series B | 2403565 | 5255324 | 9961889 | |
Feb 11, 2021 | 2874231 | Series A | 5194757 | 7113516 |
View details of Ensoma's funding rounds and investors
Ensoma's founders and board of directors
Founder? Claim ProfileThe founders of Ensoma are Andre Lieber and Hans Peter Kiem.
Here are the details of Ensoma's key team members:
- Andre Lieber: Co-Founder of Ensoma.
- Hans Peter Kiem: Co-Founder of Ensoma.
- Kush Parmar: Co-Founder of Ensoma.
View details of Ensoma's Founder profiles and Board Members
Ensoma's employee count trend
Ensoma has 57 employees as of Apr 26. Here is Ensoma's employee count trend over the years:
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Ensoma's Competitors and alternates
Top competitors of Ensoma include Alnylam, Spark Therapeutics and Strand Therapeutics. Here is the list of Top 10 competitors of Ensoma, ranked by Tracxn score:
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Rank | Company Details | Short Description | Total Funding | Investors | Tracxn Score |
|---|---|---|---|---|---|
1st | Alnylam 2002, Cambridge (United States), Public | Developer of RNA interference-based therapeutics for multiple disorders | $17M | 79/100 | |
2nd | Spark Therapeutics 2013, Philadelphia (United States), Acquired | Developer of gene therapy for rare diseases | $82.8M | 73/100 | |
3rd | Strand Therapeutics 2017, Cambridge (United States), Series B | Provider of platform to deliver mRNA therapeutics for multi functional treatments | $256M | 71/100 | |
4th | Insitro 2018, San Francisco (United States), Series C | Developer of machine learning platform for drug discovery and development | $643M | 70/100 | |
5th | Forge Biologics 2020, Columbus (United States), Acquired | Developer of gene therapeutic solutions for treating multiple diseases | $330M | 70/100 | |
6th | Passage Bio 2017, Philadelphia (United States), Public | Developer of gene therapies for CNS rare diseases | $226M | 69/100 | |
7th | Ultragenyx 2010, Novato (United States), Acquired | Developer of therapeutics for the treatment of rare and ultra-rare metabolic diseases | $135M | 69/100 | |
8th | Generation Bio 2016, Cambridge (United States), Acquired | Developer of gene therapies for rare liver and eye diseases | $236M | 69/100 | |
9th | ElevateBio 2018, Cambridge (United States), Series D | Provider of transnational research for portfolio of cell and gene therapy | $1.25B | 68/100 | |
10th | Krystal Biotech 2015, Pittsburgh (United States), Public | Developer of genetic medicines to treat rare diseases | $11.3M | 67/100 | |
64th | Ensoma 2019, Boston (United States), Series B | Developer of in vivo hematopoietic stem cell engineering for genomic medicine | $205M | 58/100 |
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Ensoma's Investments and acquisitions
Ensoma has acquired Twelve Bio. Ensoma has not made any investments as of now.News related to Ensoma
Media has covered Ensoma for a total of 8 events in the last 1 year, 4 of them have been about company updates and 1 about partnerships.
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Ensoma Announces First Patient Dosed in Phase 1/2 Clinical Trial of EN-374 for Treatment of X-CGDBusiness Wire•Dec 01, 2025•Ensoma
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Filevine Secures $400M in Funding to Enhance AI Legal PlatformLawnext•Sep 23, 2025•Insight Partners, The Halo Fund, Accel, Filevine and 14 others
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Ensoma secures $53M to advance EN-374 clinical milestones & in vivo HSC engineering pipeline.Financial Times•Sep 22, 2025•Ensoma, Gilead
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