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About Brookside Capital

Brookside Capital is a venture capital firm founded in 1989. It is primarily based out of San Francisco, United States. As of Jan 2016, Brookside Capital has invested in 27 companies. It primarily invests in Series C round in United States based startups. Its investments are spread across a wide range of sectors from Life Sciences to Enterprise Applications and High Tech. Most recently it participated in the $***** Series E round of Anaplan Overall, Brookside Capital portfolio has seen 1 unicorn, 6 IPOs and 17 acquisitions including key companies like DocuSign, PTC Therapeutics and Anaplan. A lot of funds co-invest with Brookside Capital, with names like Wellington sharing a substantial percentage of its portfolio.
Key Metrics
Portfolio Locations
Rounds of Entry
Series C, Series B & 6 more
Portfolio Acquisitions
Portfolio Unicorns

Brookside Capital's List of Top Investments

Brookside Capital has a portfolio of 27 companies, one of which is a Unicorn. Their most notable investments are in Thumbplay and DocuSign.Their portfolio spans across United States, China and Singapore. They have invested in Life Sciences, Enterprise Applications, High Tech and 7 other sectors, across stages such as Series C, Series B  and 6 more. Here is the list of top investments by Brookside Capital:
Provider of electronic signature and intelligent agreement management platform solutions. The platform offers tools for contract lifecycle management, agreement preparation, and agreement workflow automation. It provides features such as electronic notarization, web forms, and multi-channel delivery options. The platform extends its capabilities through integrations, APIs, and a mobile application.

Key facts about DocuSign

  • Founded Year: 2003
  • Location: San Francisco (United States)
  • Annual Revenue: $1B+ as on Jan 31, 2026
  • Stage: Public
  • Total Funding till date: $520M
  • Employee Count: 8,527 as on Jul 31, 2026
  • Investors: HTIF, Glynn Capital and 90 Others
  • Latest Funding Round: Post IPO, Jul 20, 2020, $*****
  • Highlight: Public
Developer of small molecule drugs for the treatment of rare diseases. The company's lead product Ataluren is an orally administered small-molecule drug for the treatment of cystic fibrosis and Duchenne muscular dystrophy caused by nonsense mutations. Also, developing anticancer and antibacterial drugs.

Key facts about PTC Therapeutics

  • Founded Year: 1998
  • Location: South Plainfield (United States)
  • Annual Revenue: $1B+ as on Dec 31, 2025
  • Stage: Public
  • Total Funding till date: $248M
  • Employee Count: 1,150 as on Jul 31, 2026
  • Investors: Brookside Capital, BB Biotech and 28 Others
  • Latest Funding Round: Post IPO, May 16, 2023, $*****
  • Highlight: Public
Provider of cloud-based platform for scenario planning, analysis, and reporting. The platform offers applications for finance, sales, marketing, supply chain, and human resources. It provides data management, modeling, and planning experience capabilities. The platform also features AI agents for real-time scenario modeling.

Key facts about Anaplan

  • Founded Year: 2006
  • Location: San Francisco (United States)
  • Annual Revenue: $500M - $1B as on Jan 31, 2022
  • Last Known Valuation: $*****
  • Stage: Acquired
  • Total Funding till date: $300M
  • Employee Count: 2,963 as on Jul 31, 2026
  • Investors: HTIF, Meritech and 28 Others
  • Latest Funding Round: Series F, Dec 05, 2017, $*****
  • Highlight: Acquired
Developer of gene therapy for rare diseases. It offers engineered adeno associated viruses to deliver the target gene sequence to the patient for RPE-65 mediated inherited retinal dystrophies. The company is also developing therapies for choroideremia, hemophilia A&B, and neurodegenerative diseases such as Batten's disease.

Key facts about Spark Therapeutics

  • Founded Year: 2013
  • Location: Philadelphia (United States)
  • Annual Revenue: $50M - $100M as on Dec 31, 2018
  • Last Known Valuation: $*****
  • Stage: Acquired
  • Total Funding till date: $82.8M
  • Employee Count: 304 as on Mar 31, 2026
  • Investors: T. Rowe Price, Brookside Capital and 6 Others
  • Latest Funding Round: Series B, May 23, 2014, $*****
  • Highlight: Acquired
Youku Tudou is a video streaming platform. It uses tri-networks integration model applied on this video-sharing platform that enables users to search, view, and share high-quality video content quickly and easily across multiple devices. Youku Tudou’s offerings are not limited to original user-generated content. Its online video content ranges from user-generated content and self-produced serials to licensed professional content. Offers a space for both individuals and institutions to upload and share their moments, independent films, viral videos, and anything else they create.

Key facts about Youku Tudou

Brookside Capital's Investments by Stage

Brookside Capital is primarily an Late Stage Investor investor majorly investing in Series C (9) rounds where average round size is $503M, Series B (6) rounds where average round size is $311M and Series A (3) rounds where average round size is $129M.
Here are Brookside Capital's investments by stage:
Stage of entry
No. of Investments
Series C
9
Series B
6
Series A
3
Series E
3
Series D
2
Others
3
Breakdown of Brookside Capital's investments by stage of entrySeries C (9)Series B (6)
Note: We have considered here, only first round of investments

Brookside Capital's Investments by Sector

Brookside Capital has a diverse portfolio, with companies operating in the Life Sciences, Enterprise Applications, High Tech, Media & Entertainment and Consumer. Notably, it has invested in 26 Tech companies, 22 Enterprise (B2B) companies, 6 Consumer (B2C) companies and at least 6 companies focusing on Software.
Here are Brookside Capital's investments by sector:
Sector
No. of Investments
Life Sciences
15
Enterprise Applications
5
High Tech
4
Media & Entertainment
4
Consumer
2
Others
10
Breakdown of Brookside Capital's investments by sectorsLife Sciences (15)Enterprise Applic... (5)
Note: We have considered here, only first round of investments

Brookside Capital's Investments by Geography

Brookside Capital has made most investments in United States (24), followed by China where it has made 1 investment.
Here are Brookside Capital's investments by geography:
Country
No. of Investments
United States
24
China
1
Singapore
1
Breakdown of Brookside Capital's investments by countriesUnited States (24)China (1)
Note: We have considered here, only first round of investments

Brookside Capital's recent investments

Brookside Capital has not made any investment in 2026 so far.
Here are the most recent investments by Brookside Capital:
Date
Company
Location
Round Details
Round Amount
Co-Investors
Jan 14, 2016
United States
Series E
6562
Sep 08, 2015
United States
Series C
7602
Jul 23, 2015
United States
Series B
1780
Jul 22, 2015
Singapore
Series A
9749
  [+5]
May 28, 2015
United States
Series D
4670

Unicorns in Brookside Capital's Portfolio

Brookside Capital has 1 unicorn in its portfolio - MuleSoft. The most recent unicorn in their portfolio is MuleSoft which became a unicorn in 2015.
Here is a list of unicorns in Brookside Capital's portfolio:
Tracxn Score
Company
Short Description
Founded year
Sector
Location
Company Stage
First Investment/ Acquisition Details
61
Cloud based API management platform
2006
San Francisco
Series G
vjvoijv

IPOs and Publicly Listed companies in Brookside Capital's Portfolio

6 of Brookside Capital's portfolio companies have become public. DocuSign got listed on the National Association of Securities Dealers Automated Quotations (NASDAQ), in Apr 2018 at marketcap of $4.41B and Voyager Therapeutics got listed on the National Association of Securities Dealers Automated Quotations (NASDAQ) at marketcap of $364M.
Here are Brookside Capital's portfolio companies that went public:
Company
IPO Date
First Invested on
First Round of Investment
Round Size
Apr 27, 2018
Apr 30, 2015
Series F
2602
Nov 11, 2015
Apr 22, 2015
Series B
5411
Sep 18, 2015
Jan 23, 2015
Series C
5327
Jun 20, 2014
Dec 04, 2013
Series E
1069
Jun 20, 2013
Mar 07, 2013
Series J
3988

Acquired companies in Brookside Capital's Portfolio

17 companies from Brookside Capital's portfolio have been acquired. The most recent acquisition was Radius Health in Jan 2026 by B-FLEXION for $*****.
Here are Brookside Capital's portfolio companies that got acquired most recently:
Company
Acquisition Date
First Invested on
First Round of Investment
Round Size
Jan 12, 2026
May 25, 2011
Series C
4727
Nov 25, 2024
Jan 17, 2007
Series C
4211
Mar 06, 2023
Feb 28, 2014
Series C
8406
Jan 19, 2023
Nov 30, 2006
Series B
3785
Mar 20, 2022
May 23, 2014
Series D
5970

Co-investors of Brookside Capital

Over the past 26 years, 235 investors have co-invested in Brookside Capital's portfolio companies. This includes funds and angels.

  • Invested before Brookside CapitalAccel, Sapphire Ventures and 96 others have invested in rounds before Brookside Capital. There are 2 companies where Accel has invested before Brookside Capital and 2 companies where Sapphire Ventures has invested before Brookside Capital.
  • Top Co-investors of Brookside Capital80 investors entered a company along with Brookside Capital. These include investors like Wellington (3 companies).
  • Invested after Brookside CapitalA total of 57 investors have invested in Brookside Capital's portfolio after their investments. Top Investors include Foresite Capital (2 companies), QVT Family Office (2 companies) and Janus Henderson Investors (2 companies).

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FAQs about Brookside Capital

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