Rhythm Pharmaceuticals - About the company
Rhythm Pharmaceuticals is a public company based in Boston (United States), founded in 2010 by Bart Henderson. It operates as a Developer of peptide therapeutics for the treatment of rare genetic deficiencies. Rhythm Pharmaceuticals has raised $84M in funding from Third Rock Ventures and Pfizer Venture Investments. The company has 319 active competitors, including 89 funded and 114 that have exited. Its top competitors include companies like BridgeBio, Alnylam and Alexion.
Company Details
Developer of peptide therapeutics for the treatment of rare genetic deficiencies. It offers a lead peptide product candidate setmelanotide which is a potent, first-in-class melanocortin-4 receptor (MC4R) agonist for the treatment of Prader-Willi syndrome (PWS) and pro-opiomelanocortin deficiency obesity.
- Email ID
- *****@rhythmtx.com
- Registered Address
- Boston, Massachusetts
Key Metrics
Founded Year
2010
Location
Boston, United States
Stage
Public
Total Funding
$84M in 9 rounds
Latest Funding Round
Investors
Ranked
9th among 319 active competitors
Annual Revenue
$100M - $500M as on Dec 31, 2025
Employee Count
479 as on Jul 31, 2026
Investment & Acquisitions
Exit Details
Public
Legal entities associated with Rhythm Pharmaceuticals
Rhythm Pharmaceuticals is associated with 3 legal entities given below:
Legal Entity Name | Date of Incorporation | Revenue | Latest Employee Count | Documents |
|---|---|---|---|---|
Rhythm Pharmaceuticals, Inc. CIN: 1649904 , United States, Active | Feb 25, 2013 | $100M - $500M (As on Dec 31, 2025) | - | - |
RHYTHM PHARMAEUTICALS CIN: 0798.109.961 , Belgium, Active | Feb 01, 2023 | - | - | - |
Rhythm Pharmaceuticals Inc CIN: 462159271 , United States, Active | Dec 31, 1999 | - | 191 (As on Dec 31, 2024) | - |
Rhythm Pharmaceuticals's IPO details
Rhythm Pharmaceuticals got listed on Oct 05, 2017.
Click here to take a look at Rhythm Pharmaceuticals's IPO in detail
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Rhythm Pharmaceuticals's funding and investors
Rhythm Pharmaceuticals has raised a total funding of $84M over 9 rounds. Its first funding round was on Mar 15, 2010. Its latest funding round was a Post IPO round on Apr 01, 2024 for $*****. 1 investor participated in its latest round. Rhythm Pharmaceuticals has 10 institutional investors.
Here is the list of recent funding rounds of Rhythm Pharmaceuticals:
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Date of Funding | Funding Amount | Round Name | Post-Money Valuation | Revenue Multiple | Lead Investors | Other Investors |
|---|---|---|---|---|---|---|
Apr 01, 2024 | 5252192 | Post IPO | 3893443 | 7891265 | 3902285 | 7786460 |
Feb 16, 2017 | 5255130 | Venture Debt | 5293174 | 7048829 | 8650259 | |
Jul 10, 2015 | 3647158 | Grant (prize money) | 1777944 | 7266573 | 5865551 |
View details of Rhythm Pharmaceuticals's funding rounds and investors
Rhythm Pharmaceuticals' founders and board of directors
Founder? Claim ProfileThe founders of Rhythm Pharmaceuticals is Bart Henderson. David Meeker is the CEO of Rhythm Pharmaceuticals.
Here are the details of Rhythm Pharmaceuticals' key team members:
- Bart Henderson: Former Founder & President of Rhythm Pharmaceuticals and founder of 1 other company.
- David Meeker: CEO of Rhythm Pharmaceuticals. Contact Info: 1 email address
View details of Rhythm Pharmaceuticals's Founder profiles and Board Members
Rhythm Pharmaceuticals' employee count trend
Rhythm Pharmaceuticals has 479 employees as of Jul 26. Here is Rhythm Pharmaceuticals's employee count trend over the years:
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Rhythm Pharmaceuticals's Competitors and alternates
Top competitors of Rhythm Pharmaceuticals include BridgeBio, Alnylam and Alexion. Here is the list of Top 10 competitors of Rhythm Pharmaceuticals, ranked by Tracxn score:
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Rank | Company Details | Short Description | Total Funding | Investors | Tracxn Score |
|---|---|---|---|---|---|
1st | BridgeBio 2015, Palo Alto (United States), Public | Developer of therapeutics for the treatment of genetic diseases | $434M | 81/100 | |
2nd | Alnylam 2002, Cambridge (United States), Public | Developer of RNA interference-based therapeutics for multiple disorders | $17M | 79/100 | |
3rd | Alexion 1992, Zurich (Switzerland), Acquired | Developer of therapies for patients with devastating and rare diseases | $133M | 79/100 | |
4th | PTC Therapeutics 1998, South Plainfield (United States), Public | Developer of small molecule drugs for the treatment of rare diseases | $248M | 77/100 | |
5th | Spark Therapeutics 2013, Philadelphia (United States), Acquired | Developer of gene therapy for rare diseases | $82.8M | 73/100 | |
6th | Blueprint Medicines 2008, Cambridge (United States), Acquired | Developer of selective kinase inhibitors for patients with genomically defined cancers | $115M | 72/100 | |
7th | Bluebird Bio 1992, Cambridge (United States), Acquired | Developer of gene therapies for severe genetic and rare diseases | $136M | 71/100 | |
8th | Agios Pharmaceuticals 2008, Cambridge (United States), Public | Developer of therapeutics in the field of cancer metabolism and rare genetic disorders of metabolism | $120M | 70/100 | |
9th | Rhythm Pharmaceuticals 2010, Boston (United States), Public | Developer of peptide therapeutics for the treatment of rare genetic deficiencies | $84M | 70/100 | |
10th | Orchard Therapeutics 2015, London (United Kingdom), Acquired | Developer of gene therapies for treating rare diseases | $440M | 70/100 |
Looking for more details on Rhythm Pharmaceuticals's competitors? Click here to see the top ones
Rhythm Pharmaceuticals's Investments and acquisitions
Rhythm Pharmaceuticals has acquired Xinvento. Rhythm Pharmaceuticals has not made any investments as of now.Reports related to Rhythm Pharmaceuticals
Here is the latest report on Rhythm Pharmaceuticals's geography:
News related to Rhythm Pharmaceuticals
Media has covered Rhythm Pharmaceuticals for a total of 35 events in the last 1 year, 26 of them have been about company updates.
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M&T Bank Corp Invests $9.20 Million in Rhythm Pharmaceuticals, Inc. $RYTMMarketBeat•Apr 25, 2026•Rhythm Pharmaceuticals, M&T Bank
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Rhythm Pharma Receives Positive CHMP Opinion for IMCIVREE for Acquired HOGlobeNewswire•Mar 26, 2026•Rhythm Pharmaceuticals
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Rhythm Pharma Receives FDA Approval for IMCIVREE® in Hypothalamic ObesityGlobeNewswire•Mar 19, 2026•Rhythm Pharmaceuticals
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