About OS Fund
OS Fund is a venture capital firm founded in 2014. It is primarily based out of Chicago, United States. As of Mar 2022, OS Fund has invested in 44 companies. It primarily invests in Series A round in United States based startups. Its investments are spread across a wide range of sectors from High Tech to Life Sciences and Enterprise Applications. Most recently it participated in the $***** Series B round of Arzeda Overall, OS Fund portfolio has seen 2 unicorns, 1 IPO and 7 acquisitions including key companies like Ginkgo Bioworks, Synthego and JUST Egg. A lot of funds co-invest with OS Fund, with names like AME Cloud Ventures sharing a substantial percentage of its portfolio. OS Fund has team of 4 people including 1 partners.Key Metrics
Team Members
Portfolio Count
Portfolio Sectors
Portfolio Locations
Rounds of Entry
Series A, Series B & 2 more
Portfolio IPOs
Portfolio Soonicorns
OS Fund's List of Top Investments
OS Fund has a portfolio of 44 companies, including 2 unicorns. Their most notable investments are in Verge Genomics and Planetary Resources.Their portfolio spans across United States, Canada, India and 1 more locations. They have invested in High Tech, Life Sciences, Enterprise Applications and 19 other sectors, across stages such as Series A, Series B and 2 more. Here is the list of top investments by OS Fund:Provider of precision medicine, preventative health assessments, and longevity care. The company offers comprehensive health assessments to detect life-threatening conditions early. It focuses on data-driven, personalized healthcare designed to uncover health risks. The company provides services to help individuals take control of their health.
Key facts about Human Longevity
- Founded Year: 2013
- Location: San Diego (United States)
- Valuation: $*****
- Stage: Series B
- Total Funding till date: $409M
- Employee Count: 81 as on Mar 31, 2026
- Investors: Celgene, Amino Capital and 20 Others
- Latest Funding Round: Series B, Aug 21, 2024, $*****
- Highlight: Editors' Pick
Autonomous labs for biotechnology, empowering scientists to design the living world. They provide autonomous labs and cloud lab services, enabling scientists to automate experimental work and focus on insight and creativity. The company offers solutions and datapoints services to design experiments and address research goals. Their autonomous systems lift the burden of manual lab work, empowering scientists to ask critical questions. They provide hardware, software, support, and cloud lab resources. The company's vision is to enable programming biology, curing diseases, and growing everything imaginable. This is a B2B tech company offering SaaS solutions for biotechnology and pharmaceutical industries.
Key facts about Ginkgo Bioworks
- Founded Year: 2008
- Location: Boston (United States)
- Annual Revenue: $170M as on Dec 31, 2025
- Stage: Public
- Total Funding till date: $796M
- Employee Count: 638 as on Mar 31, 2026
- Investors: Owl Rock, Avitas Capital and 53 Others
- Latest Funding Round: Grant (prize money), Dec 13, 2023, $*****
- Highlight: Public
3. Synthego
Developer of CRISPR-engineered cell and gene therapies. Their flagship product "CRISPR evolution", is a portfolio of synthetic guide RNA designed for CRISPR genome editing and research. Its products include CRISPR/Cas9 EZ RNA kit in either a single guide RNA format, or a two-part tracrRNA format and optional chemical modifications, full-length synthetic RNAs, and screening libraries based on the CRISPRevolution platform. It uses extensive automation in its production pipeline. The company is working in collaboration with many universities to conduct CRISPR research in applications such as stem cells, primary human cells, and mouse embryos.
Key facts about Synthego
- Founded Year: 2012
- Location: Redwood City (United States)
- Stage: Acquired
- Total Funding till date: $460M
- Employee Count: 167 as on Mar 31, 2026
- Investors: RA Capital Management, Wellington and 30 Others
- Latest Funding Round: Series E, Feb 17, 2022, $*****
- Highlight: Acquired

4. Truvian
Developer of automated benchtop blood testing system for labs. The company has developed a patented diagnostic platform, that enables comprehensive blood testing using chemistries, immunoassays, and hematology assays using a small sample of blood.
Key facts about Truvian
- Founded Year: 2015
- Location: San Diego (United States)
- Stage: Series C
- Total Funding till date: $208M
- Employee Count: 113 as on Mar 31, 2026
- Investors: Spring Creek Partners, General Catalyst and 21 Others
- Latest Funding Round: Series C, Jul 17, 2024, $*****
- Highlight: Editors' Pick
5. Change
Provider of an online platform for creating and sharing petitions. This platform allows individuals and organizations to initiate petitions on various issues, garner support from others, and engage with decision-makers. The platform facilitates the sharing of petitions through social networks and other channels to build momentum. The goal is to enable users to collectively advocate for change on matters of importance to them.
Key facts about Change
- Founded Year: 2005
- Location: India
- Stage: Series C
- Total Funding till date: $73.4M
- Employee Count: 337 as on Mar 31, 2026
- Investors: Western Technology Investment, Rethink Impact and 23 Others
- Latest Funding Round: Angel, May 26, 2017, $*****
- Highlight: Editors' Pick
OS Fund's Year-on-Year Investment Trends
OS Fund has invested in 44 companies over the last 12 years, with an average of 1 new investment annually in the last 10 years. Its most recent first time investment was in Kenota Health and most recent follow-on round was in Arzeda.Year | No. of Investments | ||
|---|---|---|---|
1st Round | Follow-on | Total | |
2026 (YTD) | 0 | 0 | 0 |
2025 | 0 | 0 | 0 |
2024 | 0 | 0 | 0 |
2023 | 0 | 0 | 0 |
2022 | 0 | 1 | 1 |
2021 | 0 | 0 | 0 |
2020 | 1 | 0 | 1 |
2019 | 1 | 0 | 1 |
2018 | 6 | 1 | 7 |
2017 | 1 | 0 | 1 |
OS Fund's Investments by Stage
OS Fund has made 11 investments in Series A stage with an average round size of $19.9M, 6 investments in Series B stage with an average round size of $24.8M, 2 investments in Seed stage with an average round size of $4.42M and 2 investments in Series C stage with an average round size of $86.5M.Stage of entry | No. of Investments |
|---|---|
Series A | 11 |
Series B | 6 |
Seed | 2 |
Series C | 2 |
Note: We have considered here, only first round of investments
OS Fund's Investments by Sector
OS Fund has a diverse portfolio, with companies operating in the Life Sciences, High Tech, Enterprise Applications, HealthTech and Vertical SaaS. Notably, it has invested in 42 Tech companies, 39 Enterprise (B2B) companies, 19 Software companies and at least 8 companies focusing on Saas.Sector | No. of Investments |
|---|---|
Life Sciences | 14 |
High Tech | 13 |
Enterprise Applications | 6 |
HealthTech | 5 |
Vertical SaaS | 4 |
Others | 24 |
Note: We have considered here, only first round of investments
OS Fund's Investments by Geography
OS Fund has made most investments in United States (20), followed by Canada where it has made 1 investment.Country | No. of Investments |
|---|---|
United States | 20 |
Canada | 1 |
Note: We have considered here, only first round of investments
OS Fund's recent investments
OS Fund has not made any investment in 2026 so far.Here are the most recent investments by OS Fund:
Date | Company | Location | Round Details | Round Amount | Co-Investors |
|---|---|---|---|---|---|
Mar 30, 2022 | United States | Series B | 7959 | [+6] | |
Dec 07, 2020 | Canada | Series A | 7840 | [+6] | |
Sep 24, 2019 | United States | Seed | 3484 | [+4] | |
Sep 21, 2018 | United States | Series C | 6727 | [+2] | |
Jul 17, 2018 | United States | Series B | 3521 | [+2] |
Unicorns in OS Fund's Portfolio
OS Fund has 2 unicorns in its portfolio - Pivot Bio and JUST Egg. The most recent unicorn in their portfolio is Pivot Bio. It became a unicorn in 2021, 4 years before OS Fund first invested in it.Here is a list of unicorns in OS Fund's portfolio:
Tracxn Score | Company | Short Description | Founded year | Sector | Location | Company Stage | First Investment/ Acquisition Details |
|---|---|---|---|---|---|---|---|
58 | Developer of microbial nitrogen products designed for crop nutrition enhancement | 2010 | Berkeley | Series D | szeodjn | ||
67 | Manufacturer of plant-based egg substitutes | 2011 | San Francisco | Series F | lsdvwqh |
IPOs and Publicly Listed companies in OS Fund's Portfolio
1 of OS Fund's portfolio company became public - Ginkgo Bioworks. It got listed on the New York Stock Exchange (NYSE), in Sep 2021.Here are OS Fund's portfolio companies that went public:
Company | IPO Date | First Invested on | First Round of Investment | Round Size |
|---|---|---|---|---|
Sep 17, 2021 | Mar 18, 2015 | Series A | 2155 |
Acquired companies in OS Fund's Portfolio
7 companies from OS Fund's portfolio have been acquired. The most recent acquisition was Synthego in Jun 2025 by Perceptive Advisors for $*****.Here are OS Fund's portfolio companies that got acquired most recently:
Company | Acquisition Date | First Invested on | First Round of Investment | Round Size |
|---|---|---|---|---|
Jun 26, 2025 | Dec 21, 2016 | Series B | 2627 | |
Mar 16, 2023 | - | - | 3900 | |
Apr 22, 2022 | Mar 21, 2014 | Series B | 2483 | |
Jun 03, 2019 | - | - | 5077 | |
Oct 31, 2018 | Nov 15, 2016 | Series A | 9616 |
Team profile of OS Fund
OS Fund has a team of 4 members including 1 Partner and 1 Principal located in Canada. OS Fund's team does not sit on the board of any company as of now.Co-investors of OS Fund
Over the past 12 years, 254 investors have co-invested in OS Fund's portfolio companies. This includes funds and angels.
- Invested before OS Fund: Y Combinator, National Science Foundation and 75 others have invested in rounds before OS Fund. There are 5 companies where Y Combinator has invested before OS Fund and 5 companies where National Science Foundation has invested before OS Fund.
- Top Co-investors of OS Fund: 93 investors entered a company along with OS Fund. These include investors like AME Cloud Ventures (5 companies).
- Invested after OS Fund: A total of 84 investors have invested in OS Fund's portfolio after their investments. Top Investors include Gates (3 companies), HHS (2 companies) and Perceptive Advisors (2 companies).
Recent News related to OS Fund
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Arzeda Closes $33M in Series B FundingFinSMEs•Mar 31, 2022•Arzeda, Continental Grain Company, Lewis & Clark Agrifood, Circulate Capital and 4 others
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DNA-based Data Storage and Computation Provider CATALOG, Founded by MIT Scientists, Raises $10 MillionGlobeNewswire•Sep 09, 2020•Catalog Technologies, Horizons Ventures, Airbus Ventures, New Enterprise Associates and 4 others
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A-Alpha Bio Closes $2.8M Seed FundingFinSMEs•Sep 24, 2019•A-Alpha Bio, AME Cloud Ventures, BOOM, Madrona and 4 others
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uBiome is jumping into therapeutics with a healthy $83 million in Series C financingTechCrunch+•Sep 21, 2018•uBiome, OS Fund, 8VC, Y Combinator and 1 other
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OS Fund Raising $250M to Support Entrepreneurs Building Deep Tech to Solve Global ProblemsBusiness Wire•Aug 07, 2018•OS Fund
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Lygos Raises $15.5 Million to Accelerate Delivery of Clean and Sustainable Biology-Based Performance MaterialsGlobeNewswire•Jul 17, 2018•Lygos, IA Ventures, First Round Capital, OS Fund and 1 other
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Verge Genomics Announces $32 Million Series A to Lead Artificial Intelligence-Driven Drug DiscoveryBusiness Wire•Jul 16, 2018•Verge Genomics, DFJ, WuXi AppTec, ALS Investment Fund and 2 others
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Boston’s Catalog Secures $9 Million in Funding to Advance DNA Data Storage TechnologyBioSpace•Jun 26, 2018•Catalog Technologies, New Enterprise Associates, OS Fund, Day One Ventures and 7 others
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NuMat Technologies Closes $12.4M Funding Round to Accelerate Commercialization of Molecularly Engineered ProductsBusiness Wire•Apr 26, 2018•NuMat, OS Fund, Osage Partners, Tin Shed Ventures and 3 others
