About Prolog Ventures
Prolog Ventures is a venture capital firm founded in 2000. It is primarily based out of Newark, United States. As of Feb 2024, Prolog Ventures has invested in 38 companies. It primarily invests in Series A round in United States based startups. Its investments are spread across a wide range of sectors from Life Sciences to High Tech and Food and Agriculture Tech. Most recently it participated in the $***** Seed round of Simple Planet Overall, Prolog Ventures portfolio has seen 1 IPO and 17 acquisitions including key companies like NxThera, Veran Medical and CoverCress. A lot of funds co-invest with Prolog Ventures, with names like Prelude Ventures sharing a substantial percentage of its portfolio. Prolog Ventures has team of 2 people including 1 partners.Key Metrics
Team Members
Portfolio Count
Portfolio Sectors
Portfolio Locations
Rounds of Entry
Series A, Seed & 4 more
Portfolio IPOs
Portfolio Acquisitions
Prolog Ventures' List of Top Investments
Prolog Ventures has a portfolio of 38 companies. Their most notable investments are in Veran Medical and Veran Medical.Their portfolio spans across United States, Canada and South Korea. They have invested in Life Sciences, High Tech, Food and Agriculture Tech and 9 other sectors, across stages such as Series A, Seed and 4 more. Here is the list of top investments by Prolog Ventures:1. Zeel
Marketplace that delivers in-home, same-day, on-demand massage services on Android and iPhone. Customers pay a set price (including tax & tip) through credit card. Platform has a network of vetted therapists - background checked, licensed and insured who get appointments and payments via the app that tracks their availability and location using GPS.
Key facts about Zeel
- Founded Year: 2010
- Location: New York City (United States)
- Valuation: $*****
- Stage: Series B
- Total Funding till date: $27.4M
- Employee Count: 936 as on Sep 30, 2026
- Investors: Western Technology Investment, HT Ventures and 46 Others
- Latest Funding Round: Series B, 2018, $*****
- Highlight: Editors' Pick
2. Benson Hill
Developer of soybean genetics, seeds, and related programs for agriculture. The company offers soybean varieties and partner programs for grain processors. It provides independent testing to validate soybean genetics. Industries served include animal feed, food, and fuel production.
Key facts about Benson Hill
- Founded Year: 2012
- Location: St. Louis (United States)
- Annual Revenue: $100M - $500M as on Dec 31, 2023
- Last Known Valuation: $*****
- Stage: Deadpooled
- Total Funding till date: $407M
- Employee Count: 108 as on Mar 31, 2026
- Investors: Collab Fund, Tao Capital Partners and 32 Others
- Latest Funding Round: Conventional Debt, Jan 04, 2022, $*****
3. NxThera
Developer of thermal therapy for Benign Prostatic Hyperplasia(BPH). The Rezum System uses Radiofrequency energy to create sterile water vapor to address BPH by delivering targeted, controlled doses of stored thermal energy through heat convection directly to the region of the prostate gland that houses the obstructive tissue that causes BPH. The therapy can be used in an outpatient procedure.
Key facts about NxThera
- Founded Year: 2008
- Location: Maple Grove (United States)
- Last Known Valuation: $*****
- Stage: Acquired
- Total Funding till date: $148M
- Employee Count: 77 as on Dec 31, 2017
- Investors: Ally Bridge Group, Mitsui Global Investment and 8 Others
- Latest Funding Round: Series D, Jul 19, 2017, $*****
- Highlight: Acquired
Veran Medical Technologies develops medical devices for detection and minimally invasive treatment of lung cancer. Veran's IG4 Plug-N-Play Delivery System uses electromagnetic navigation and respiratory tracking to enable physicians to target small lesions. Its IG4 Platform allows clinicians to visualize information integrated with a CT dataset, such as respiration, contrast-enhanced structures, PET, and ultrasound.
Key facts about Veran Medical
- Founded Year: 2005
- Location: St. Louis (United States)
- Stage: Acquired
- Total Funding till date: $155M
- Employee Count: 10 - 49 as on Mar 01, 2026
- Investors: Versant Ventures, Vensana Capital and 13 Others
- Latest Funding Round: Conventional Debt, Dec 19, 2018, $*****
- Highlight: Acquired
5. NeuroLutions
NeuroLutions is developing devices based on brain-computer interface technology restoring functions in patients disabled due to neurological injury. It is developing a robotic glove that the user can wear it on their hand and a headset.
Key facts about NeuroLutions
- Founded Year: 2007
- Location: St. Louis (United States)
- Stage: Series A
- Total Funding till date: $28.3M
- Employee Count: 92 as on Mar 31, 2026
- Investors: Techlink Ventures, Ascension Ventures and 6 Others
- Latest Funding Round: Series A, Feb 14, 2025, $*****
- Highlight: Editors' Pick
Prolog Ventures' Year-on-Year Investment Trends
Prolog Ventures has invested in 38 companies over the last 24 years, with an average of 1 new investment annually in the last 10 years. Its most recent first time investment was in Simple Planet and most recent follow-on round was in Benson Hill.Year | No. of Investments | ||
|---|---|---|---|
1st Round | Follow-on | Total | |
2026 (YTD) | 0 | 0 | 0 |
2025 | 0 | 0 | 0 |
2024 | 1 | 0 | 1 |
2023 | 0 | 0 | 0 |
2022 | 0 | 0 | 0 |
2021 | 0 | 0 | 0 |
2020 | 2 | 2 | 4 |
2019 | 1 | 0 | 1 |
2018 | 1 | 2 | 3 |
2017 | 0 | 4 | 4 |
Prolog Ventures' Investments by Stage
Prolog Ventures is primarily an Early Stage Investor investor majorly investing in Series A (17) rounds where average round size is $109M, Seed (7) rounds where average round size is $13.6M and Series B (6) rounds where average round size is $80.6M.Stage of entry | No. of Investments |
|---|---|
Series A | 17 |
Seed | 7 |
Series B | 6 |
Post IPO | 1 |
Series C | 1 |
Others | 1 |
Note: We have considered here, only first round of investments
Prolog Ventures' Investments by Sector
Prolog Ventures has a diverse portfolio, with companies operating in the Life Sciences, High Tech, Enterprise Applications, Food and Agriculture Tech and HealthTech. Notably, it has invested in 31 Tech companies, 25 Enterprise (B2B) companies, 14 Software companies and at least 10 companies focusing on Consumer (B2C).Sector | No. of Investments |
|---|---|
Life Sciences | 22 |
High Tech | 8 |
Enterprise Applications | 7 |
Food and Agriculture Tech | 4 |
HealthTech | 4 |
Others | 15 |
Note: We have considered here, only first round of investments
Prolog Ventures' Investments by Geography
Prolog Ventures has made most investments in United States (31), followed by Canada where it has made 1 investment.Country | No. of Investments |
|---|---|
United States | 31 |
Canada | 1 |
South Korea | 1 |
Note: We have considered here, only first round of investments
Prolog Ventures' recent investments
Prolog Ventures has not made any investment in 2026 so far.Here are the most recent investments by Prolog Ventures:
Filter this listDate | Company | Location | Round Details | Round Amount | Co-Investors |
|---|---|---|---|---|---|
Feb 14, 2024 | South Korea | Seed | 1947 | [+7] | |
Oct 29, 2020 | United States | Series D | 9022 | [+11] | |
Apr 15, 2020 | Canada | Series A | 7026 | - | |
Mar 05, 2020 | United States | Series C | 3347 | [+2] | |
Feb 28, 2020 | United States | Series A | 9795 | [+2] |
IPOs and Publicly Listed companies in Prolog Ventures' Portfolio
1 of Prolog Ventures' portfolio company became public - AirXpanders. It got listed on the Australian Securities Exchange (ASX), in Jul 2006 at marketcap of $82.1MHere are Prolog Ventures' portfolio companies that went public:
Company | IPO Date | First Invested on | First Round of Investment | Round Size |
|---|---|---|---|---|
Jul 20, 2006 | May 17, 2012 | Post IPO | 6726 |
Acquired companies in Prolog Ventures' Portfolio
17 companies from Prolog Ventures' portfolio have been acquired. The most recent acquisition was Spindrift in Jan 2025 by Gryphon Investors for $*****.Here are Prolog Ventures' portfolio companies that got acquired most recently:
Company | Acquisition Date | First Invested on | First Round of Investment | Round Size |
|---|---|---|---|---|
Jan 16, 2025 | May 01, 2014 | Seed | 2084 | |
Jun 07, 2023 | Apr 15, 2020 | Series A | 9000 | |
Aug 01, 2022 | Dec 21, 2018 | Series A | 7407 | |
Mar 31, 2021 | - | - | 7459 | |
Dec 04, 2020 | May 13, 2008 | Seed | 7644 |
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Team profile of Prolog Ventures
Prolog Ventures has a team of 2 members. Prolog Ventures' team does not sit on the board of any company as of now.Co-investors of Prolog Ventures
Over the past 24 years, 201 investors have co-invested in Prolog Ventures's portfolio companies. This includes funds and angels.
- Invested before Prolog Ventures: BioGenerator, Missouri Technology and 34 others have invested in rounds before Prolog Ventures. There are 3 companies where BioGenerator has invested before Prolog Ventures and 2 companies where Missouri Technology has invested before Prolog Ventures.
- Top Co-investors of Prolog Ventures: 81 investors entered a company along with Prolog Ventures. These include investors like Prelude Ventures (3 companies).
- Invested after Prolog Ventures: A total of 84 investors have invested in Prolog Ventures's portfolio after their investments. Top Investors include HHS (4 companies), Oxford Finance (3 companies) and Boston Scientific (2 companies).
Recent News related to Prolog Ventures
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Cultured Meat Company Simple Planet Secures Cumulative Investment Of Approximately 10 Billion WonStartupn•Feb 14, 2024•A Simple Planet, POSCO Capital, DCP, EASY BIO and 10 others
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Cleanslate Uv Raises $8.4 Million Cad As Covid-19 Increases Demand For Device SanitizationBetaKit•Apr 20, 2020•CleanSlate UV, Prolog Ventures
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CoverCress scores $5M follow-on equity investmentBiofuels Digest•Apr 13, 2020•CoverCress, Fulcrum Global Capital, Prelude Ventures, Leaps by Bayer and 2 others
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Kinnos, which makes colorized disinfectant to ensure surfaces are covered, just landed $6 million in fundingICrowdNewswire•Mar 06, 2020•Kinnos, Prolog Ventures, Partnership Fund for New York City, Golden Seeds and 2 others
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Spindrift Raises $29.8M in Funding RoundBevNET.com•Mar 06, 2020•Spindrift, VMG Partners, Prolog Ventures, KarpReilly and 2 others
