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Manifold Bio - About the company

Manifold Bio is a series A company based in United States, founded in 2018 by Gleb Kuznetsov and Shane Lofgren. It operates as a Developer of tissue-targeted therapeutics using in vivo screening and AI design. Manifold Bio has raised $78.2M in funding from Playground Global and Triatomic. The company has 831 active competitors, including 56 funded and 50 that have exited. Its top competitors include companies like Alloy Therapeutics, Maiva Pharma and Simulations Plus.

Company Details

Developer of tissue-targeted therapeutics using in vivo screening and AI design. The company combines protein design with testing in living systems to sculpt biologics' properties. It has invented molecular tracking technologies to expand in vivo measurement of biologics. The company designs proteins for function and specificity, translating designs into biologics through synthesis and display. It is building a predictive model of living systems to map biomolecule behavior.
Email ID
*****@manifold.bio
Key Metrics
Founded Year
2018
Location
Stage
Series A
Total Funding
$78.2M in 3 rounds
Latest Funding Round
Ranked
Employee Count
68 as on Jun 30, 2026
Investment & Acquisitions
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Manifold Bio's funding and investors

Manifold Bio has raised a total funding of $78.2M over 3 rounds. Its first funding round was on Aug 10, 2020. Manifold Bio has 10 institutional investors.

Here is the list of recent funding rounds of Manifold Bio:
Date of Funding
Funding Amount
Round Name
Post-Money Valuation
Revenue Multiple
Lead Investors
Other Investors
Nov 18, 2024
6451384
Series A
8126781
1601394
3498482
3772205
Jun 13, 2022
7641431
Series A
6241000
9003679
9826329
Aug 10, 2020
8633487
Seed
2245684
8460888
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Manifold Bio's founders and board of directors

Founder? Claim Profile
The founders of Manifold Bio are Gleb Kuznetsov and Shane Lofgren. Gleb Kuznetsov is the CEO of Manifold Bio.
Here are the details of Manifold Bio's key team members:

Manifold Bio's employee count trend

Manifold Bio has 68 employees as of Jun 26. Here is Manifold Bio's employee count trend over the years:
Employee count trend for Manifold Bio
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Manifold Bio's Competitors and alternates

Top competitors of Manifold Bio include Alloy Therapeutics, Maiva Pharma and Simulations Plus. Here is the list of Top 10 competitors of Manifold Bio, ranked by Tracxn score:
Rank
Company Details
Short Description
Total Funding
Investors
Tracxn Score
1st
Logo for Alloy Therapeutics
Alloy Therapeutics
2017, Lexington (United States), Series E
Provider of drug discovery services
$157M
63/100
2nd
Logo for Maiva Pharma
Maiva Pharma
1996, Hosur (India), Late Stage
Manufacturer of sterile injectables
$125M
61/100
3rd
Logo for Simulations Plus
Simulations Plus
1996, Lancaster (United States), Public
Developer of modeling and simulation software and consulting services provider
-
60/100
4th
Developer of tissue-targeted therapeutics using in vivo screening and AI design
$78.2M
54/100
5th
Logo for CILcare
CILcare
2014, Montpellier (France), Series A
Service to develop health products aiming to diagnose, prevent, delay the progression or treat hearing loss and tinnitus
$42.3M
53/100
6th
Logo for VelaVigo
VelaVigo
2021, Shanghai (China), Seed
Biotechnology research company developing biological drugs
$160M
53/100
7th
Logo for ArcaScience
ArcaScience
2018, Paris (France), Seed
Developer of AI models for patient-centric insights in drug development
$7M
52/100
8th
Logo for Viva Biotech
Viva Biotech
2006, Shanghai (China), Public
Research services focused on drug discovery and development
-
51/100
9th
Logo for Arctoris
Arctoris
2016, Abingdon (United Kingdom), Seed
Provider of automated wet lab biology research and data generation services
$3.93M
51/100
10th
Logo for Superluminal Medicines
Superluminal Medicines
2022, Boston (United States), Series A
Generative biological and chemical company focused on drug discovery
$158M
50/100
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Manifold Bio's Investments and acquisitions

Manifold Bio has a total of 1 investment in UXLINK. Manifold Bio has not made any acquisitions as of now.

Reports related to Manifold Bio

Here is the latest report on Manifold Bio's sector:

News related to Manifold Bio

Media has covered Manifold Bio for a total of 4 events in the last 1 year, 2 of them have been about partnerships and 1 about company updates.
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