About B2B E-Commerce sector in United States
The B2B E-Commerce sector in United States comprises 3.1K companies, including 742 funded companies having collectively raised $28.2B in venture capital money and private equity. Out of these, 521 are Series A+ funded, and 13 have achieved unicorn status.
B2B E-Commerce sector in United States has seen 365 acquisitions and 29 IPOs. This represents almost 12.7% of all such companies - which is higher than the 5.3% exit rate of tech companies in general.
This sector includes b2B E-Commerce covers companies that enable businesses to buy goods and services from other businesses.
B2B E-Commerce sector is also known as Wholesale Ecommerce.
Includes companies that operate as marketplaces, listing platforms, e-distributors or any other platforms that connect businesses for the exchange of goods and services. Also, includes companies that facilitate B2B E-Commerce by providing technology or software solutions. Does not cover companies that provide software solutions for SCM, business processes, manufacturers, healthcare companies, and offline players are excluded.
Top B2B E-Commerce Companies in United States
There are 3,097 B2B E-Commerce startups in United States which include Amazon, Alibaba, ezCater, VTEX, AppDirect. Out of these, 742 startups are funded, with 521 having secured Series A+ funding, and 13 achieving unicorn status.
Over the past 10 years, an average of 114 new companies have been launched annually. Notably, several of these startups have been founded by alumni of Harvard University, Harvard Business School and Massachusetts Institute of Technology.
Here is the list of top B2B E-Commerce startups in United States
1. Amazon
Online marketplace offering multi-category products. The product catalog includes home care, fashion, beauty, stationery, electronic, pet supplies, groceries, healthcare, fitness, books, mom and baby care products, and more. The app offers features such as real-time delivery tracking, product views, price drop notifications, and more. It also offers services like e-books, Alexa smart speakers, and Twitch live streaming alongside its retail platform. The mobile app is available for both Android and iOS users.
Key facts about Amazon
- Founded Year: 1994
- Location: Seattle (United States)
- Stage: Public
- Total Funding till date: $8M
- Investors: Kleiner Perkins, US Capital Partners and 48 Others
- Latest Funding Round: Conventional Debt, Oct 09, 2013, $*****
- Tracxn Score: 85/100 What is this?
- Competitors Rank: 1 of 209 Competitors
2. Alibaba
Online B2B cross-border marketplace platform for multi-category products. The product catalog includes healthcare, gadgets, chemicals, sports, fashion, industrial machinery, home appliances, raw material, and more. The mobile application is available for both iOS and Android users.
Key facts about Alibaba
- Founded Year: 1999
- Location: New York City (United States)
- Stage: Public
- Investors: Investor Growth Capital, TDF Capital and 45 Others
- Tracxn Score: 80/100 What is this?
- Competitors Rank: 2 of 191 Competitors
3. ezCater
Online catering marketplace for enterprises. The platform allows users to discover and order food from local caterers for corporate events and private parties. It provides concierge ordering, employee meal planning, event catering, and more.
Key facts about ezCater
- Founded Year: 2007
- Location: Boston (United States)
- Stage: Series D
- Total Funding till date: $439M
- Investors: Spinnaker Trust, Launchpad Venture Group and 22 Others
- Latest Funding Round: Series D, Dec 15, 2021, $*****
- Tracxn Score: 79/100 What is this?
- Competitors Rank: 1 of 61 Competitors
4. VTEX
Provider of SaaS-based collaborative commerce solutions for brands and retailers. The platform offers a proprietary cloud-based platform and tools to manage products, content, user experience, checkout, logistics, merchandising, marketing, order management, personalized promotion, multiple fulfillment options, and more. The company also offers an omnichannel solution with features including an order management system, content management system, logistics, inventory, pricing and campaign management, and more.
Key facts about VTEX
- Founded Year: 2000
- Location: New York City (United States)
- Stage: Public
- Total Funding till date: $365M
- Investors: Lone Pine Capital, Tiger Global Management and 8 Others
- Latest Funding Round: Series D, Sep 28, 2020, $*****
- Tracxn Score: 75/100 What is this?
- Competitors Rank: 1 of 227 Competitors
5. AppDirect
Online application marketplace. It provides a cloud service marketplace that enables users to find, buy, sell, and distribute web-based cloud applications and services. The platform provides billing, payment, and reseller management solutions. It caters its solution to industries such as finance, manufacturing, communication service providers, and more.
Key facts about AppDirect
- Founded Year: 2009
- Location: San Francisco (United States)
- Stage: Series F
- Total Funding till date: $438M
- Investors: Mithril, Stingray and 11 Others
- Latest Funding Round: Conventional Debt, Jan 09, 2024, $*****
- Tracxn Score: 74/100 What is this?
- Competitors Rank: 1 of 94 Competitors
Companies founded year-on-year in the B2B E-Commerce sector in United States
200 B2B E-Commerce startups in United States were founded in 2020 - this is the most number of startups founded in any year in the last 10 years.
- Total Number of Companies
Year | No. of companies |
|---|---|
2025 | 1 |
2024 | 16 |
2023 | 82 |
2022 | 115 |
2021 | 155 |
2020 | 200 |
2019 | 159 |
2018 | 151 |
2017 | 138 |
2016 | 127 |
Stage-wise distribution of B2B E-Commerce sector companies in United States
Out of the total 3,097 B2B E-Commerce companies in United States, 742 have secured funding. Among them, 521 have reached Series A or higher, and 457 to Series B or beyond.
Founded - 3,097
Funded - 742
Series A+ - 521
Series B+ - 457
Series C+ - 423
Company Stage | No. of companies |
|---|---|
Founded | 3,097 |
Funded | 742 |
Series A+ | 521 |
Series B+ | 457 |
Series C+ | 423 |
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Funding Trends in the B2B E-Commerce sector in United States
Total funding year-on-year in the B2B E-Commerce sector in United States
The B2B E-Commerce sector in United States saw a total funding of more than $19B in the last 10 years. The most amount of funding was in 2021 at more than $7.9B.
- Total Funding
Year | Total Funding |
|---|---|
2025 | $59.6M |
2024 | $349M |
2023 | $1.15B |
2022 | $1.72B |
2021 | $7.9B |
2020 | $2.22B |
2019 | $2.16B |
2018 | $2.23B |
2017 | $397M |
Recent Funding Rounds in B2B E-Commerce in United States
In the year 2025, till December 2025, B2B E-Commerce companies in United States have raised $209M in equity funding across 19 rounds.
In the same period last year (i.e. till December 2024), B2B E-Commerce companies in United States had raised $242M across 34 rounds.
So, 2025 has seen a 13.84% drop in funding in B2B E-Commerce companies in United States as compared to 2024.
Here are some recent, important funding rounds in B2B E-Commerce companies in United States:
Company | Round Raised | Amount Raised | Funding Date | Investors |
|---|---|---|---|---|
Series A | 6969 | Dec 10, 2025 | ||
Series A | 5400 | Nov 20, 2025 | - | |
Series A | 1048 | Nov 18, 2025 | ||
Series I | 2382 | Nov 17, 2025 | ||
Series A | 6931 | Aug 20, 2025 |
Top Investors in B2B E-Commerce in United States
Y Combinator is the top investor in B2B E-Commerce companies in United States based on number of companies invested.
Here are some top investors in B2B E-Commerce companies in United States:
Investor | Location | Top Portfolio Companies |
|---|---|---|
Mountain View (United States) | ||
Palo Alto (United States) | ||
New York City (United States) | ||
New York City (United States) | ||
New York City (United States) |
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M&A activity in B2B E-Commerce sector in United States
In the year 2025, till December 2025, 18 acquisitions happened in B2B E-Commerce sector in United States. Last year, in 2024, a total of 17 acquisitions happened in B2B E-Commerce sector in United States.
Here are some recent, important acquisitions in B2B E-Commerce sector in United States:
Company | Acquisition Type | Acquisition Date | Acquirers |
|---|---|---|---|
Business Acquisition | Dec 18, 2025 | ||
Business Acquisition | Dec 05, 2025 | ||
Business Acquisition | Oct 28, 2025 | ||
Business Acquisition | Oct 27, 2025 | ||
Business Acquisition | Oct 17, 2025 |
Acquisition trends in B2B E-Commerce sector in United States
Here are the acquisition trends in B2B E-Commerce sector in United States:
- Total Number of Acquisitions
Year | No. of companies |
|---|---|
2025 | 14 |
2024 | 17 |
2023 | 14 |
2022 | 53 |
2021 | 47 |
2020 | 26 |
2019 | 26 |
2018 | 29 |
2017 | 28 |
2016 | 25 |
IPOs in B2B E-Commerce in United States
In the year 2021, till July 2021, 3 IPOs happened in B2B E-Commerce sector in United States.
Here are some recent, important IPOs in B2B E-Commerce sector in United States:
Company | IPO Date | Exchange Symbol |
|---|---|---|
Jul 21, 2021 | New York Stock Exchange (NYSE) | |
Jun 30, 2021 | National Association of Securities Dealers Automated Quotations (NASDAQ) | |
Mar 24, 2021 | National Association of Securities Dealers Automated Quotations (NASDAQ) | |
Aug 05, 2020 | National Association of Securities Dealers Automated Quotations (NASDAQ) | |
Jun 10, 2019 | Canadian Securities Exchange (CSE) |
Colleges which produce the most B2B E-Commerce companies in United States
Companies founded by alumni from top colleges in the B2B E-Commerce in United States
Most number of B2B E-Commerce startups in United States have been founded by alumni from Harvard University, Harvard Business School and Massachusetts Institute of Technology.
College | No. of companies |
|---|---|
Harvard University | 28 |
Harvard Business School | 18 |
Massachusetts Institute of Technology | 18 |
University of Pennsylvania | 18 |
Stanford University | 17 |
University of California (Berkeley) | 17 |
Columbia University | 14 |
University of California (Los Angeles) | 13 |
Wharton School | 12 |
Cornell University | 10 |
Total funding in B2B E-Commerce companies founded by alumni from top colleges in United States
In the last 10 years, University of California (Berkeley) graduates' B2B E-Commerce companies in United States have raised the most funding among top colleges. University of Waterloo and University of Oxford alumni are second.
College | Total Funding |
|---|---|
University of California (Berkeley) | $1.43B |
University of Waterloo | $1.32B |
University of Oxford | $1.32B |
Yale University | $1.3B |
Harvard University | $1.12B |
Massachusetts Institute of Technology | $747M |
Tel Aviv University | $684M |
McGill University | $592M |
Carnegie Mellon University | $460M |
University of Pennsylvania | $393M |
Top News in B2B E-Commerce in United States
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Misionero Unveils Rebrand of Garden Life Washed & Trimmed LinePerishableNews.com•Oct 10, 2025•Misionero
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Amazon One Medical Launches Perimenopause & Menopause VisitsHIT Consultant•Sep 25, 2025•One Medical, Amazon
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XR integrates with Amazon DSP for High-Performance Video CampaignsMarTech Series•Sep 10, 2025•XR Extreme Reach, Amazon
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Do it Best, True Value launch 1st integrated Fall Market with record attendanceLBM Journal•Sep 08, 2025•DoItBest
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Amazon Ads Unveils Innovations for UEFA Champions League & NBA on Prime VideoChannelX•Sep 03, 2025•Evri, Chelsea FC, Arsenal, Latitude and Longitude and 9 others
